| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tetracycline (hydrochloride)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | 0.1264 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0671978 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0457386 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0403339 |
| TXNIP | thioredoxin interacting protein | 0.0384757 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.036822 |
| RPS3 | ribosomal protein S3 | 0.0349055 |
| EGR1 | early growth response 1 | 0.0343711 |
| RPL12 | ribosomal protein L12 | 0.0341124 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0339145 |
| LDHA | lactate dehydrogenase A | 0.031757 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0311843 |
| RPL18 | ribosomal protein L18 | 0.0304457 |
| B2M | beta-2-microglobulin | 0.0301061 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0294944 |
| FOSL1 | FOS-like antigen 1 | 0.0288587 |
| NDRG1 | N-myc downstream regulated 1 | 0.0286001 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0279238 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0279025 |
| KRT19 | keratin 19, type I | 0.0275934 |
| NFIA | nuclear factor I/A | 0.0274035 |
| STC2 | stanniocalcin 2 | 0.0257352 |
| KLF6 | Kruppel-like factor 6 | 0.0245176 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0244438 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0244125 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0242903 |
| RPLP0 | ribosomal protein, large, P0 | 0.0240927 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0229747 |
| TMEM41B | transmembrane protein 41B | 0.022827 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0224753 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0222975 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0220631 |
| RPL36 | ribosomal protein L36 | 0.0215983 |
| VIM | vimentin | 0.0214478 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.021245 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0207788 |
| EHBP1 | EH domain binding protein 1 | 0.0207787 |
| PRELID2 | PRELI domain containing 2 | 0.0207538 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0205117 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0203328 |
| EZR | ezrin | 0.0202153 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0201465 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0199794 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0197815 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0197602 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0193953 |
| RPS25 | ribosomal protein S25 | 0.0192009 |
| EDN1 | endothelin 1 | 0.0191865 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.0190368 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0185052 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0183036 |
| MKI67 | marker of proliferation Ki-67 | 0.0181389 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0181044 |
| MT2A | metallothionein 2A | 0.0180677 |
| HKDC1 | hexokinase domain containing 1 | 0.0179404 |
| TNPO3 | transportin 3 | 0.0179096 |
| SBF2 | SET binding factor 2 | 0.0175795 |
| FAT1 | FAT atypical cadherin 1 | 0.0175582 |
| IER2 | immediate early response 2 | 0.0175079 |
| GOLGA2 | golgin A2 | 0.0170723 |
| RUNX1 | runt-related transcription factor 1 | 0.0170632 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0169682 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0169008 |
| RPL37 | ribosomal protein L37 | 0.0168596 |
| CENPF | centromere protein F, 350/400kDa | 0.0167369 |
| ANXA3 | annexin A3 | 0.0166431 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.016552 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0164158 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | 0.0161944 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0161423 |
| ADM | adrenomedullin | 0.0160643 |
| MAP4 | microtubule-associated protein 4 | 0.0160052 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0158249 |
| PKP4 | plakophilin 4 | 0.0156716 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0155015 |
| ARFGEF1 | ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) | 0.0152704 |
| RPL31 | ribosomal protein L31 | 0.0151271 |
| CERS6 | ceramide synthase 6 | 0.0151162 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0148901 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0148261 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0147796 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0146873 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | 0.0144946 |
| FRMD5 | FERM domain containing 5 | 0.0143613 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like | 0.0143335 |
| HYOU1 | hypoxia up-regulated 1 | 0.014272 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0140444 |
| RPLP1 | ribosomal protein, large, P1 | 0.0139416 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0138109 |
| RPS6 | ribosomal protein S6 | 0.013731 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | 0.0137224 |
| CLDN4 | claudin 4 | 0.0136697 |
| NHSL1 | NHS-like 1 | 0.0134952 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0134407 |
| NIPSNAP2 | nipsnap homolog 2 | 0.01344 |
| S100A11 | S100 calcium binding protein A11 | 0.0133528 |
| SCFD1 | sec1 family domain containing 1 | 0.0133307 |
| CMTM8 | CKLF-like MARVEL transmembrane domain containing 8 | 0.013304 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0132769 |
| RPLP2 | ribosomal protein, large, P2 | 0.0132447 |
| Symbol | Name | Standardized Value |
|---|---|---|
| UBC | ubiquitin C | -0.145093 |
| PTMA | prothymosin, alpha | -0.113259 |
| KRT8 | keratin 8, type II | -0.107813 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0919357 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0836143 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0781699 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0777287 |
| ACTN4 | actinin, alpha 4 | -0.0732835 |
| RBM39 | RNA binding motif protein 39 | -0.0707699 |
| AHNAK | AHNAK nucleoprotein | -0.0660563 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0646919 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0616786 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0613255 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0607637 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0607083 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0549447 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0547558 |
| NCOA3 | nuclear receptor coactivator 3 | -0.0530855 |
| TOP1 | topoisomerase (DNA) I | -0.0503413 |
| CCND1 | cyclin D1 | -0.0493512 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0472152 |
| ACTG1 | actin gamma 1 | -0.0469302 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0458496 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0448825 |
| PCBP2 | poly(rC) binding protein 2 | -0.044441 |
| GNAS | GNAS complex locus | -0.0436385 |
| ZNF207 | zinc finger protein 207 | -0.0417213 |
| RPS27A | ribosomal protein S27a | -0.0406332 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0404832 |
| S100A10 | S100 calcium binding protein A10 | -0.0402741 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0400771 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0399366 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0396849 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0395108 |
| RHEB | Ras homolog enriched in brain | -0.0383997 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0380698 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0380008 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0370033 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0366956 |
| CANX | calnexin | -0.0365599 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0353952 |
| TMSB4X | thymosin beta 4, X-linked | -0.0353771 |
| MEF2A | myocyte enhancer factor 2A | -0.0352956 |
| POTEF | POTE ankyrin domain family, member F | -0.0341873 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0335894 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0327574 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0327355 |
| ANXA2 | annexin A2 | -0.0326273 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0325528 |
| NCKAP1 | NCK-associated protein 1 | -0.0325028 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0314802 |
| MATR3 | matrin 3 | -0.0311603 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0309431 |
| SPAG9 | sperm associated antigen 9 | -0.0306336 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0306319 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0306063 |
| FUS | FUS RNA binding protein | -0.0302229 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0294501 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0286376 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | -0.0286267 |
| ZNF292 | zinc finger protein 292 | -0.0286211 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0282183 |
| YAP1 | Yes-associated protein 1 | -0.0281577 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0278003 |
| RCOR1 | REST corepressor 1 | -0.0277692 |
| SET | SET nuclear proto-oncogene | -0.0274801 |
| EMP1 | epithelial membrane protein 1 | -0.0271299 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0267953 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0266726 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0266237 |
| USP15 | ubiquitin specific peptidase 15 | -0.0265775 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0264526 |
| RAB10 | RAB10, member RAS oncogene family | -0.0262016 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0261272 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0260418 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0260329 |
| SDC4 | syndecan 4 | -0.02598 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0259189 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0259009 |
| CD2AP | CD2-associated protein | -0.0257127 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.025696 |
| FAM3C | family with sequence similarity 3, member C | -0.025556 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0254706 |
| OLA1 | Obg-like ATPase 1 | -0.0254551 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0254525 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.025366 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0253446 |
| MED13 | mediator complex subunit 13 | -0.0253028 |
| ANKRD11 | ankyrin repeat domain 11 | -0.025282 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0250473 |
| PERP | PERP, TP53 apoptosis effector | -0.0249498 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0246333 |
| RPL8 | ribosomal protein L8 | -0.0244719 |
| RHOA | ras homolog family member A | -0.0242296 |
| RPL14 | ribosomal protein L14 | -0.0239761 |
| MYO5B | myosin VB | -0.0238062 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0236641 |
| JMJD1C | jumonji domain containing 1C | -0.0236531 |
| DIAPH1 | diaphanous-related formin 1 | -0.0235674 |
| TMEM123 | transmembrane protein 123 | -0.0234123 |
