| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tetracycline (hydrochloride)_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD36 | CD36 molecule (thrombospondin receptor) | 0.227876 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0899325 |
| OXR1 | oxidation resistance 1 | 0.0761544 |
| AREG | amphiregulin | 0.0643043 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0608998 |
| FAT1 | FAT atypical cadherin 1 | 0.0605522 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0530225 |
| EREG | epiregulin | 0.0523265 |
| KITLG | KIT ligand | 0.0513084 |
| RPS12 | ribosomal protein S12 | 0.0503416 |
| RAD51B | RAD51 paralog B | 0.0476417 |
| EGFR | epidermal growth factor receptor | 0.0433665 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0428216 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0390677 |
| GNAT3 | guanine nucleotide binding protein, alpha transducing 3 | 0.0388268 |
| HMGB2 | high mobility group box 2 | 0.0361484 |
| AXIN2 | axin 2 | 0.0351637 |
| RPS2 | ribosomal protein S2 | 0.0347894 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0329963 |
| RPS3 | ribosomal protein S3 | 0.0322174 |
| NEK7 | NIMA-related kinase 7 | 0.0319779 |
| RNF43 | ring finger protein 43 | 0.0314077 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0311718 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | 0.0302811 |
| MED13L | mediator complex subunit 13-like | 0.0293396 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.029337 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0291283 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0289551 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.028141 |
| FRMD5 | FERM domain containing 5 | 0.0278969 |
| EVA1C | eva-1 homolog C (C. elegans) | 0.0276836 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0275736 |
| BCL2L1 | BCL2-like 1 | 0.0265 |
| TGFB2 | transforming growth factor, beta 2 | 0.0253472 |
| EDAR | ectodysplasin A receptor | 0.0251479 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0250037 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0248901 |
| YAP1 | Yes-associated protein 1 | 0.0246633 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0244692 |
| ENO1 | enolase 1, (alpha) | 0.0243694 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.024238 |
| RPS7 | ribosomal protein S7 | 0.023681 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0234253 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0234095 |
| ARRDC3 | arrestin domain containing 3 | 0.0233056 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0232857 |
| ANXA1 | annexin A1 | 0.0231652 |
| ZNRF3 | zinc and ring finger 3 | 0.0229232 |
| MKI67 | marker of proliferation Ki-67 | 0.0222104 |
| RPS17 | ribosomal protein S17 | 0.021855 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0218366 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.021196 |
| CENPF | centromere protein F, 350/400kDa | 0.0211369 |
| EPHA2 | EPH receptor A2 | 0.021055 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0204461 |
| RPLP2 | ribosomal protein, large, P2 | 0.0203226 |
| YBX3 | Y box binding protein 3 | 0.0203013 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0197745 |
| RPLP0 | ribosomal protein, large, P0 | 0.0196077 |
| NT5DC3 | 5'-nucleotidase domain containing 3 | 0.0194036 |
| IPO7 | importin 7 | 0.0193714 |
| CEP152 | centrosomal protein 152kDa | 0.0193262 |
| RANBP9 | RAN binding protein 9 | 0.0192885 |
| DCUN1D3 | DCN1, defective in cullin neddylation 1, domain containing 3 | 0.0192388 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0191874 |
| ATXN1 | ataxin 1 | 0.0190449 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0187513 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0187187 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0186457 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0183849 |
| FN1 | fibronectin 1 | 0.0183441 |
| SLTM | SAFB-like, transcription modulator | 0.0180218 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0178955 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0178921 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0177823 |
| LDHA | lactate dehydrogenase A | 0.0177635 |
| RPL36 | ribosomal protein L36 | 0.0172588 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0172375 |
| MYOF | myoferlin | 0.0171451 |
| TOP1 | topoisomerase (DNA) I | 0.0170375 |
| CCDC6 | coiled-coil domain containing 6 | 0.0170018 |
| MXI1 | MAX interactor 1, dimerization protein | 0.016986 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.016877 |
| RACK1 | receptor for activated C kinase 1 | 0.0168616 |
| VIM | vimentin | 0.0167886 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0167559 |
| BBX | bobby sox homolog (Drosophila) | 0.0166188 |
| RPL18 | ribosomal protein L18 | 0.0164867 |
| RPL22L1 | ribosomal protein L22-like 1 | 0.0164536 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0164109 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0160459 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0160261 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.016014 |
| MT2A | metallothionein 2A | 0.0158621 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0151584 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0151098 |
| IL18 | interleukin 18 | 0.0147698 |
| PSAT1 | phosphoserine aminotransferase 1 | 0.0147542 |
| GPR137B | G protein-coupled receptor 137B | 0.0147003 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0145491 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.140092 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.126144 |
| ACTG1 | actin gamma 1 | -0.119272 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.103582 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.094877 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0919294 |
| UBC | ubiquitin C | -0.0841663 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0790128 |
| RCOR1 | REST corepressor 1 | -0.06856 |
| NDRG1 | N-myc downstream regulated 1 | -0.0660661 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0638806 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0627793 |
| LAMB3 | laminin, beta 3 | -0.0565341 |
| LMO7 | LIM domain 7 | -0.0534534 |
| EMP1 | epithelial membrane protein 1 | -0.0490852 |
| AHNAK | AHNAK nucleoprotein | -0.0481751 |
| IER3 | immediate early response 3 | -0.0464656 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0458271 |
| CDK13 | cyclin-dependent kinase 13 | -0.0440193 |
| EGR1 | early growth response 1 | -0.0435722 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0427955 |
| CANX | calnexin | -0.0422739 |
| RBM25 | RNA binding motif protein 25 | -0.0411584 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0409302 |
| HMGA2 | high mobility group AT-hook 2 | -0.0394154 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0384496 |
| ANXA2 | annexin A2 | -0.0382444 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0379892 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0377155 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0368784 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0363363 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0361067 |
| NUP50 | nucleoporin 50kDa | -0.0354186 |
| SNX9 | sorting nexin 9 | -0.0341758 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0337961 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0337941 |
| GPC5 | glypican 5 | -0.0336202 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0332616 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0330585 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0329536 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | -0.0324043 |
| LAMA4 | laminin, alpha 4 | -0.0312576 |
| RPL35A | ribosomal protein L35a | -0.0310602 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0293716 |
| HDAC2 | histone deacetylase 2 | -0.0293422 |
| SETD5 | SET domain containing 5 | -0.0293361 |
| CMIP | c-Maf inducing protein | -0.0291536 |
| S100A6 | S100 calcium binding protein A6 | -0.029105 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0287357 |
| RPL8 | ribosomal protein L8 | -0.0286068 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.028278 |
| PERP | PERP, TP53 apoptosis effector | -0.0279174 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0276053 |
| COG5 | component of oligomeric golgi complex 5 | -0.0270629 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0260833 |
| DENND1A | DENN/MADD domain containing 1A | -0.0257578 |
| CUX1 | cut-like homeobox 1 | -0.0256757 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.025465 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0248063 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0246162 |
| PCBP2 | poly(rC) binding protein 2 | -0.0245011 |
| TRAF3 | TNF receptor-associated factor 3 | -0.0243945 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0241082 |
| RPS27A | ribosomal protein S27a | -0.0241003 |
| GLG1 | golgi glycoprotein 1 | -0.023615 |
| RPS6 | ribosomal protein S6 | -0.0233984 |
| CD9 | CD9 molecule | -0.0232428 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0230034 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0226355 |
| CCNI | cyclin I | -0.022532 |
| RPL32 | ribosomal protein L32 | -0.0223901 |
| EXT1 | exostosin glycosyltransferase 1 | -0.022178 |
| RREB1 | ras responsive element binding protein 1 | -0.0221451 |
| CDHR3 | cadherin-related family member 3 | -0.0219274 |
| VPS13A | vacuolar protein sorting 13 homolog A (S. cerevisiae) | -0.0215587 |
| TAOK1 | TAO kinase 1 | -0.0215332 |
| XYLT1 | xylosyltransferase I | -0.021441 |
| POTEF | POTE ankyrin domain family, member F | -0.0213726 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0206572 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0203203 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0201305 |
| RPL34 | ribosomal protein L34 | -0.0201115 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0200487 |
| RPS23 | ribosomal protein S23 | -0.0198133 |
| MT1X | metallothionein 1X | -0.0197118 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.019708 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0196425 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0194178 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0193326 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0189858 |
| SQSTM1 | sequestosome 1 | -0.0188305 |
| PHF14 | PHD finger protein 14 | -0.0186138 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0184385 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0182468 |
| KRT8 | keratin 8, type II | -0.0181626 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0178564 |
| FNIP1 | folliculin interacting protein 1 | -0.0177588 |
| YY1 | YY1 transcription factor | -0.0177478 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0177122 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0176912 |
