| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tetracycline (hydrochloride) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tetracycline (hydrochloride)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.103204 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0641505 |
| VIM | vimentin | 0.0621808 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0443036 |
| NDRG1 | N-myc downstream regulated 1 | 0.0386463 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0373584 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0368855 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0362088 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0342562 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0333555 |
| TMSB10 | thymosin beta 10 | 0.0327882 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0324596 |
| MT2A | metallothionein 2A | 0.0312331 |
| LDHA | lactate dehydrogenase A | 0.030511 |
| LOX | lysyl oxidase | 0.0302522 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0289003 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0273974 |
| RPL23 | ribosomal protein L23 | 0.0260507 |
| RUNX1 | runt-related transcription factor 1 | 0.0258139 |
| CD44 | CD44 molecule (Indian blood group) | 0.0257263 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0247996 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0239613 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0235703 |
| SMOX | spermine oxidase | 0.0234314 |
| B2M | beta-2-microglobulin | 0.0232405 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0231681 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.0219993 |
| SP3 | Sp3 transcription factor | 0.0218987 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0215161 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0211123 |
| PLPP3 | phospholipid phosphatase 3 | 0.0210628 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.020667 |
| RPS3 | ribosomal protein S3 | 0.0204804 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0201713 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.0201513 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0201251 |
| FAM13A | family with sequence similarity 13, member A | 0.02011 |
| ENO1 | enolase 1, (alpha) | 0.0200244 |
| PCBP3 | poly(rC) binding protein 3 | 0.0195378 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0194716 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0189312 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.0188614 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0187855 |
| KLF6 | Kruppel-like factor 6 | 0.0187459 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0185132 |
| PDE8A | phosphodiesterase 8A | 0.0184986 |
| DNER | delta/notch-like EGF repeat containing | 0.0184787 |
| TPI1 | triosephosphate isomerase 1 | 0.0180584 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0177819 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.0175522 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0175115 |
| TBX2 | T-box 2 | 0.017133 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0170748 |
| SMAD3 | SMAD family member 3 | 0.0169882 |
| TXNIP | thioredoxin interacting protein | 0.0168043 |
| ARF6 | ADP-ribosylation factor 6 | 0.0167769 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.016574 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0165681 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0164283 |
| SNAI2 | snail family zinc finger 2 | 0.0160416 |
| MSN | moesin | 0.015942 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0156397 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0154529 |
| RPS12 | ribosomal protein S12 | 0.0154199 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0153975 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0153603 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0148006 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0145613 |
| EFNA5 | ephrin-A5 | 0.0143137 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.014293 |
| PKM | pyruvate kinase, muscle | 0.0140085 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.013978 |
| WDR26 | WD repeat domain 26 | 0.0139695 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0139695 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0139095 |
| CLIC4 | chloride intracellular channel 4 | 0.0138419 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0137939 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0137217 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0137158 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0136801 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0135543 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0135264 |
| RTN4 | reticulon 4 | 0.0131606 |
| CDK17 | cyclin-dependent kinase 17 | 0.0131049 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0130644 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0130241 |
| PCM1 | pericentriolar material 1 | 0.012908 |
| POMP | proteasome maturation protein | 0.0128251 |
| CCDC88A | coiled-coil domain containing 88A | 0.0127185 |
| PCBP2 | poly(rC) binding protein 2 | 0.0127029 |
| MKI67 | marker of proliferation Ki-67 | 0.0123727 |
| RPL36 | ribosomal protein L36 | 0.0123583 |
| KLF12 | Kruppel-like factor 12 | 0.0123238 |
| NR2F2 | nuclear receptor subfamily 2, group F, member 2 | 0.0123189 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0122121 |
| RPL9 | ribosomal protein L9 | 0.0121663 |
| C1D | C1D nuclear receptor corepressor | 0.0121201 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.0121058 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0120635 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0120454 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.14503 |
| COL1A1 | collagen, type I, alpha 1 | -0.121708 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0954058 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0768449 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0758269 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0724388 |
| FN1 | fibronectin 1 | -0.0707739 |
| ACTG1 | actin gamma 1 | -0.0696856 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0686431 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0652383 |
| GOLGA4 | golgin A4 | -0.062723 |
| HLA-B | major histocompatibility complex, class I, B | -0.057159 |
| EMP1 | epithelial membrane protein 1 | -0.0568271 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0559935 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0499228 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0487877 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0460249 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0455349 |
| TPM4 | tropomyosin 4 | -0.0440402 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0437171 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0401626 |
| MMP12 | matrix metallopeptidase 12 | -0.0394713 |
| FBN1 | fibrillin 1 | -0.0389092 |
| COL1A2 | collagen, type I, alpha 2 | -0.0363853 |
| AHNAK | AHNAK nucleoprotein | -0.0361819 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.035062 |
| RAI14 | retinoic acid induced 14 | -0.0342643 |
| MMP1 | matrix metallopeptidase 1 | -0.0341971 |
| POTEF | POTE ankyrin domain family, member F | -0.0337305 |
| CDH13 | cadherin 13 | -0.0336983 |
| TMEM165 | transmembrane protein 165 | -0.0336714 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0326656 |
| FMNL2 | formin-like 2 | -0.0307642 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0304757 |
| CAVIN1 | caveolae associated protein 1 | -0.0301853 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0299635 |
| GREM1 | gremlin 1, DAN family BMP antagonist | -0.0298232 |
| ADM | adrenomedullin | -0.0298184 |
| MYO10 | myosin X | -0.0297964 |
| ITGA1 | integrin, alpha 1 | -0.0292782 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0292069 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0281255 |
| VCAN | versican | -0.0277697 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0276591 |
| GLIS3 | GLIS family zinc finger 3 | -0.0276341 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0276036 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0272377 |
| COL5A1 | collagen, type V, alpha 1 | -0.0255862 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0254605 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0250173 |
| COL3A1 | collagen, type III, alpha 1 | -0.0249362 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0248608 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0240314 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0239099 |
| RND3 | Rho family GTPase 3 | -0.0238186 |
| FNIP1 | folliculin interacting protein 1 | -0.0234999 |
| PRRX1 | paired related homeobox 1 | -0.0232183 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0228529 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0227337 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0226158 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0218249 |
| HELZ | helicase with zinc finger | -0.0215676 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0213497 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0212529 |
| CANX | calnexin | -0.0212189 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0210682 |
| ARHGAP10 | Rho GTPase activating protein 10 | -0.0210285 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0209904 |
| ANO10 | anoctamin 10 | -0.0207833 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0205836 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0204251 |
| NOP58 | NOP58 ribonucleoprotein | -0.0198245 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0197219 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0196132 |
| SBF2 | SET binding factor 2 | -0.0190785 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.0189886 |
| CALU | calumenin | -0.0189298 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0189125 |
| MAP4 | microtubule-associated protein 4 | -0.018872 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0186052 |
| CLMP | CXADR-like membrane protein | -0.0186024 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0184403 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0181987 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.017818 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.01779 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0176769 |
| MEIS1 | Meis homeobox 1 | -0.0173607 |
| RLF | rearranged L-myc fusion | -0.0173305 |
| FRMD4A | FERM domain containing 4A | -0.0171503 |
| RSF1 | remodeling and spacing factor 1 | -0.0170943 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.017022 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0169806 |
| MED13L | mediator complex subunit 13-like | -0.0169518 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0167978 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0167569 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0166553 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0165082 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0164914 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0164873 |
| CXCL3 | chemokine (C-X-C motif) ligand 3 | -0.0163178 |
