Thiostrepton Gene Set

Dataset CTD Gene-Chemical Interactions
Category physical interactions
Type chemical
Description A heterodetic cyclic peptide, in which the cyclisation step involves a formal lactonisation between the carboxy group of a quinaldic acid-based residue and a secondary alcohol. An antibiotic that inhibits bacterial protein synthesis. Also acts as an antitumor agent. (Chemical Entities of Biological Interest Ontology, CHEBI_29693)
External Link http://ctdbase.org/detail.go?type=chem&acc=D013883
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Genes

10 genes/proteins interacting with the chemical Thiostrepton from the curated CTD Gene-Chemical Interactions dataset.

Symbol Name
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
GSTP1 glutathione S-transferase pi 1
HMOX1 heme oxygenase 1
HSPA1A heat shock 70kDa protein 1A
HSPA6 heat shock 70kDa protein 6 (HSP70B')
MCL1 myeloid cell leukemia 1
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
TP53 tumor protein p53