| Dataset | CTD Gene-Chemical Interactions |
| Category | physical interactions |
| Type | chemical |
| Description | Thrombin is a trypsin-like serine protease protein that in humans is encoded by the F2 gene.[2][3] Prothrombin (coagulation factor II) is proteolytically cleaved to form thrombin in the coagulation cascade, which ultimately results in the stemming of blood loss. Thrombin in turn acts as a serine protease that converts soluble fibrinogen into insoluble strands of fibrin, as well as catalyzing many other coagulation-related reactions. (Experimental Factor Ontology, EFO_0003183) |
| External Link | http://ctdbase.org/detail.go?type=chem&acc=D013917 |
| Similar Terms | |
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4 genes/proteins interacting with the chemical Thrombin from the curated CTD Gene-Chemical Interactions dataset.
