Thromboangiitis Obliterans Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description OMIM mapping confirmed by DO. [LS]. (Human Disease Ontology, DOID_12918)
External Link https://www.disgenet.org/browser/0/1/0/C0040021
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Genes

121 genes associated with the disease Thromboangiitis Obliterans in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACTA2 actin, alpha 2, smooth muscle, aorta
ADAM10 ADAM metallopeptidase domain 10
AGER advanced glycosylation end product-specific receptor
AKT1 v-akt murine thymoma viral oncogene homolog 1
APOA1 apolipoprotein A-I
BCAR1 breast cancer anti-estrogen resistance 1
BCL2 B-cell CLL/lymphoma 2
BMP4 bone morphogenetic protein 4
C21ORF33 chromosome 21 open reading frame 33
CASS4 Cas scaffolding protein family member 4
CCL5 chemokine (C-C motif) ligand 5
CD14 CD14 molecule
CD34 CD34 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
COX2
CRHR1 corticotropin releasing hormone receptor 1
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSF1 colony stimulating factor 1 (macrophage)
CTNND1 catenin (cadherin-associated protein), delta 1
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL8 chemokine (C-X-C motif) ligand 8
EDN1 endothelin 1
F2 coagulation factor II (thrombin)
FABP4 fatty acid binding protein 4, adipocyte
FGF1 fibroblast growth factor 1 (acidic)
FLT1 fms-related tyrosine kinase 1
FOXP1 forkhead box P1
GATA3 GATA binding protein 3
HAVCR2 hepatitis A virus cellular receptor 2
HES1 hes family bHLH transcription factor 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGB1 high mobility group box 1
HOXB2 homeobox B2
HOXB3 homeobox B3
HPSE heparanase
ICAM1 intercellular adhesion molecule 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IL10 interleukin 10
IL13 interleukin 13
IL16 interleukin 16
IL17A interleukin 17A
IL17RC interleukin 17 receptor C
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL21R interleukin 21 receptor
IL23R interleukin 23 receptor
IL6 interleukin 6
JAG1 jagged 1
KNG1 kininogen 1
LGALS9 lectin, galactoside-binding, soluble, 9
LOC102724023 ES1 protein homolog, mitochondrial
LOX lysyl oxidase
MAPK8 mitogen-activated protein kinase 8
MICA MHC class I polypeptide-related sequence A
MKI67 marker of proliferation Ki-67
MMP3 matrix metallopeptidase 3
MYD88 myeloid differentiation primary response 88
NLRP3 NLR family, pyrin domain containing 3
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH1 notch 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR5A1 nuclear receptor subfamily 5, group A, member 1
OMG oligodendrocyte myelin glycoprotein
OPN1SW opsin 1 (cone pigments), short-wave-sensitive
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PPARG peroxisome proliferator-activated receptor gamma
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRRT2 proline-rich transmembrane protein 2
PSMD1 proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2B protein tyrosine kinase 2 beta
PTPRC protein tyrosine phosphatase, receptor type, C
PTX3 pentraxin 3, long
RBM45 RNA binding motif protein 45
SAT2 spermidine/spermine N1-acetyltransferase family member 2
SELE selectin E
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SLC38A2 solute carrier family 38, member 2
SLIT2 slit homolog 2 (Drosophila)
SMAD2 SMAD family member 2
SMC3 structural maintenance of chromosomes 3
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SRP54 signal recognition particle 54kDa
SRP9 signal recognition particle 9kDa
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
SYK spleen tyrosine kinase
TG thyroglobulin
TGFB1 transforming growth factor, beta 1
TGFB2 transforming growth factor, beta 2
THY1 Thy-1 cell surface antigen
TLR4 toll-like receptor 4
TNF tumor necrosis factor
TSHR thyroid stimulating hormone receptor
UBE2C ubiquitin-conjugating enzyme E2C
UCN urocortin
UCP1 uncoupling protein 1 (mitochondrial, proton carrier)
VCAM1 vascular cell adhesion molecule 1
VEGFA vascular endothelial growth factor A
ZNF263 zinc finger protein 263