Thrombocytosis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A myeloma and blood platelet disease that is characterized by the presence of high platelet counts in the blood. (Human Disease Ontology, DOID_2228)
External Link https://www.disgenet.org/browser/0/1/0/C0836924
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Genes

93 genes associated with the disease Thrombocytosis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACAT1 acetyl-CoA acetyltransferase 1
ADA2 adenosine deaminase 2
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
AGER advanced glycosylation end product-specific receptor
ALK anaplastic lymphoma receptor tyrosine kinase
ANTXR2 anthrax toxin receptor 2
APOB apolipoprotein B
AQP1 aquaporin 1 (Colton blood group)
AR androgen receptor
BAX BCL2-associated X protein
BCR breakpoint cluster region
BLVRB biliverdin reductase B
CALR calreticulin
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCR7 chemokine (C-C motif) receptor 7
CD177 CD177 molecule
CD274 CD274 molecule
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CPB2 carboxypeptidase B2 (plasma)
CRP C-reactive protein, pentraxin-related
CSF3 colony stimulating factor 3 (granulocyte)
CSNK1A1 casein kinase 1, alpha 1
CXCL12 chemokine (C-X-C motif) ligand 12
CXCR4 chemokine (C-X-C motif) receptor 4
DAAM1 dishevelled associated activator of morphogenesis 1
ELANE elastase, neutrophil expressed
EPO erythropoietin
F2 coagulation factor II (thrombin)
FANCB Fanconi anemia, complementation group B
FGF2 fibroblast growth factor 2 (basic)
HBB hemoglobin, beta
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HMGCL 3-hydroxymethyl-3-methylglutaryl-CoA lyase
HP haptoglobin
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
IFNA1 interferon, alpha 1
IFNA13 interferon, alpha 13
IFNA2 interferon, alpha 2
IFNG interferon, gamma
IFNGR1 interferon gamma receptor 1
IL10 interleukin 10
IL1B interleukin 1, beta
IL4 interleukin 4
IL6 interleukin 6
JAK2 Janus kinase 2
KANK1 KN motif and ankyrin repeat domains 1
LAIR1 leukocyte-associated immunoglobulin-like receptor 1
LMNA lamin A/C
MECOM MDS1 and EVI1 complex locus
MOK MOK protein kinase
MPL MPL proto-oncogene, thrombopoietin receptor
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase
MUC16 mucin 16, cell surface associated
NAAA N-acylethanolamine acid amidase
NF1 neurofibromin 1
NFE2 nuclear factor, erythroid 2
P2RY12 purinergic receptor P2Y, G-protein coupled, 12
PAEP progestagen-associated endometrial protein
PDGFA platelet-derived growth factor alpha polypeptide
PDGFB platelet-derived growth factor beta polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PMM2 phosphomannomutase 2
PRB1 proline-rich protein BstNI subfamily 1
RARS1 arginyl-tRNA synthetase 1
RPS14 ribosomal protein S14
RPS19 ribosomal protein S19
RUNX1 runt-related transcription factor 1
S100A8 S100 calcium binding protein A8
SCO2 SCO2 cytochrome c oxidase assembly protein
SF3B1 splicing factor 3b, subunit 1, 155kDa
SH2B3 SH2B adaptor protein 3
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLU7 SLU7 splicing factor homolog (S. cerevisiae)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STING1 stimulator of interferon response cGAMP interactor 1
TBC1D24 TBC1 domain family, member 24
TET2 tet methylcytosine dioxygenase 2
TFRC transferrin receptor
TGFB1 transforming growth factor, beta 1
THPO thrombopoietin
TPO thyroid peroxidase
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRNT1 tRNA nucleotidyl transferase, CCA-adding, 1
TTC37 tetratricopeptide repeat domain 37
TUBA1B tubulin, alpha 1b
TYMP thymidine phosphorylase
VEGFA vascular endothelial growth factor A
VWF von Willebrand factor
ZMPSTE24 zinc metallopeptidase STE24