Thymic Carcinoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A thymus cancer that derives_from epithelial cells. The tumor cells in a thymic carcinoma look very different from the normal cells of the thymus, grow more quickly, and have usually spread to other parts of the body when the cancer is found. (Human Disease Ontology, DOID_3284)
External Link https://www.disgenet.org/browser/0/1/0/C0205969
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Genes

73 genes associated with the disease Thymic Carcinoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
AR androgen receptor
ASXL1 additional sex combs like transcriptional regulator 1
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BRD4 bromodomain containing 4
CA9 carbonic anhydrase IX
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CD274 CD274 molecule
CD70 CD70 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CDK2 cyclin-dependent kinase 2
CDK4 cyclin-dependent kinase 4
CDKN2A cyclin-dependent kinase inhibitor 2A
CFLAR CASP8 and FADD-like apoptosis regulator
CLIC2 chloride intracellular channel 2
COX2
CYLD cylindromatosis (turban tumor syndrome)
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DPYD dihydropyrimidine dehydrogenase
EGFR epidermal growth factor receptor
ERCC1 excision repair cross-complementation group 1
FOXP3 forkhead box P3
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GTF2I general transcription factor IIi
HACD1 3-hydroxyacyl-CoA dehydratase 1
HDAC9 histone deacetylase 9
HMGB1 high mobility group box 1
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase
HOXD9 homeobox D9
HRAS Harvey rat sarcoma viral oncogene homolog
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
IDO1 indoleamine 2,3-dioxygenase 1
IGF1 insulin-like growth factor 1 (somatomedin C)
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KRAS Kirsten rat sarcoma viral oncogene homolog
LNPEP leucyl/cystinyl aminopeptidase
MGMT O-6-methylguanine-DNA methyltransferase
MSLN mesothelin
NGF nerve growth factor (beta polypeptide)
NUTM1 NUT midline carcinoma, family member 1
PBRM1 polybromo 1
PCNA proliferating cell nuclear antigen
PDCD1 programmed cell death 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLIN2 perilipin 2
PTEN phosphatase and tensin homolog
PTGES prostaglandin E synthase
PTGES2 prostaglandin E synthase 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RPL17 ribosomal protein L17
RPL17-C18ORF32 RPL17-C18orf32 readthrough
SALL3 spalt-like transcription factor 3
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SETD2 SET domain containing 2
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SMAD4 SMAD family member 4
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SORBS1 sorbin and SH3 domain containing 1
SOX2 SRY (sex determining region Y)-box 2
SPATA2 spermatogenesis associated 2
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TET2 tet methylcytosine dioxygenase 2
TP53 tumor protein p53
TUBB3 tubulin, beta 3 class III
TYMS thymidylate synthetase
VEGFA vascular endothelial growth factor A