| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| Description | A pyrimidine 2'-deoxyribonucleoside having thymine as the nucleobase. (Chemical Entities of Biological Interest Ontology, CHEBI_17748) |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/5789 |
| Similar Terms | |
| Downloads & Tools |
200 proteins with high or low expression in Thymidine relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| JAK3 | Janus kinase 3 | 1.03 |
| ADCY10 | adenylate cyclase 10 (soluble) | 0.66 |
| CASTOR2 | cytosolic arginine sensor for mTORC1 subunit 2 | 0.64 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.61 |
| TP73 | tumor protein p73 | 0.57 |
| CEP128 | centrosomal protein 128kDa | 0.54 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.53 |
| RNF220 | ring finger protein 220 | 0.52 |
| SELENOI | selenoprotein I | 0.49 |
| TPM2 | tropomyosin 2 (beta) | 0.48 |
| KMT2B | lysine (K)-specific methyltransferase 2B | 0.48 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | 0.48 |
| PRPF38A | pre-mRNA processing factor 38A | 0.48 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.46 |
| DONSON | downstream neighbor of SON | 0.46 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.46 |
| FUNDC1 | FUN14 domain containing 1 | 0.45 |
| RTN4R | reticulon 4 receptor | 0.45 |
| METTL22 | methyltransferase like 22 | 0.45 |
| GPALPP1 | GPALPP motifs containing 1 | 0.44 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | 0.43 |
| KLHL15 | kelch-like family member 15 | 0.39 |
| PCLAF | PCNA clamp associated factor | 0.39 |
| RPL17 | ribosomal protein L17 | 0.39 |
| NUP62 | nucleoporin 62kDa | 0.38 |
| ENO1 | enolase 1, (alpha) | 0.38 |
| TJP1 | tight junction protein 1 | 0.38 |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 | 0.37 |
| DCTN2 | dynactin 2 (p50) | 0.36 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | 0.35 |
| TNNC2 | troponin C type 2 (fast) | 0.35 |
| FAAH | fatty acid amide hydrolase | 0.35 |
| PIH1D1 | PIH1 domain containing 1 | 0.35 |
| POTEE | POTE ankyrin domain family, member E | 0.35 |
| SLC43A3 | solute carrier family 43, member 3 | 0.35 |
| PCNX1 | pecanex 1 | 0.35 |
| SYAP1 | synapse associated protein 1 | 0.34 |
| CHCHD4 | coiled-coil-helix-coiled-coil-helix domain containing 4 | 0.34 |
| KIF21A | kinesin family member 21A | 0.34 |
| INO80B | INO80 complex subunit B | 0.34 |
| RGL2 | ral guanine nucleotide dissociation stimulator-like 2 | 0.33 |
| GCSH | glycine cleavage system protein H (aminomethyl carrier) | 0.33 |
| DENND5A | DENN/MADD domain containing 5A | 0.32 |
| CDC37L1 | cell division cycle 37-like 1 | 0.32 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | 0.32 |
| VGF | VGF nerve growth factor inducible | 0.32 |
| NFU1 | NFU1 iron-sulfur cluster scaffold | 0.32 |
| TMC4 | transmembrane channel-like 4 | 0.32 |
| CCDC9B | coiled-coil domain containing 9B | 0.32 |
| FAM177A1 | family with sequence similarity 177, member A1 | 0.32 |
| PEX5 | peroxisomal biogenesis factor 5 | 0.31 |
| MREG | melanoregulin | 0.31 |
| RWDD1 | RWD domain containing 1 | 0.31 |
| UBQLN2 | ubiquilin 2 | 0.31 |
| ATXN7L3 | ataxin 7-like 3 | 0.31 |
| MIEF1 | mitochondrial elongation factor 1 | 0.31 |
| RBMX | RNA binding motif protein, X-linked | 0.3 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 | 0.3 |
| SELENOF | selenoprotein F | 0.3 |
| ALG3 | ALG3, alpha-1,3- mannosyltransferase | 0.3 |
| PPP1R2 | protein phosphatase 1, regulatory (inhibitor) subunit 2 | 0.3 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.29 |
| MXRA7 | matrix-remodelling associated 7 | 0.29 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.29 |
| ARL6 | ADP-ribosylation factor-like 6 | 0.29 |
| RPN2 | ribophorin II | 0.29 |
| ELFN1 | extracellular leucine-rich repeat and fibronectin type III domain containing 1 | 0.29 |
| DESI1 | desumoylating isopeptidase 1 | 0.29 |
| TRMT112 | tRNA methyltransferase 11-2 homolog (S. cerevisiae) | 0.29 |
| ATP9B | ATPase, class II, type 9B | 0.28 |
| ZNF503 | zinc finger protein 503 | 0.28 |
| CNTNAP3 | contactin associated protein-like 3 | 0.28 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.28 |
| ZNF444 | zinc finger protein 444 | 0.27 |
| TRIML2 | tripartite motif family-like 2 | 0.27 |
| RAB6D | RAB6D, member RAS oncogene family | 0.27 |
| FAT3 | FAT atypical cadherin 3 | 0.27 |
| NEMP1 | nuclear envelope integral membrane protein 1 | 0.27 |
| RPAIN | RPA interacting protein | 0.27 |
| ASF1B | anti-silencing function 1B histone chaperone | 0.27 |
| ANKRD44 | ankyrin repeat domain 44 | 0.27 |
| TPBG | trophoblast glycoprotein | 0.27 |
| PFKFB1 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | 0.27 |
| TCHP | trichoplein, keratin filament binding | 0.27 |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 | 0.27 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.27 |
| SPC24 | SPC24, NDC80 kinetochore complex component | 0.27 |
| CABLES2 | Cdk5 and Abl enzyme substrate 2 | 0.27 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.26 |
| HAUS7 | HAUS augmin-like complex, subunit 7 | 0.26 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.26 |
| SELENOK | selenoprotein K | 0.26 |
| PTMS | parathymosin | 0.26 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.26 |
| TTC7A | tetratricopeptide repeat domain 7A | 0.26 |
| BSDC1 | BSD domain containing 1 | 0.25 |
| TEN1 | TEN1 CST complex subunit | 0.25 |
| ZC3HAV1L | zinc finger CCCH-type, antiviral 1-like | 0.25 |
| RCN2 | reticulocalbin 2, EF-hand calcium binding domain | 0.25 |
| MYADM | myeloid-associated differentiation marker | 0.25 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PIP | prolactin-induced protein | -1.12 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -1.01 |
| B3GNT3 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 | -0.68 |
| ANKRD12 | ankyrin repeat domain 12 | -0.6 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.58 |
| ALDOA | aldolase A, fructose-bisphosphate | -0.51 |
| BOD1 | biorientation of chromosomes in cell division 1 | -0.5 |
| PARPBP | PARP1 binding protein | -0.49 |
| TMEM39A | transmembrane protein 39A | -0.48 |
| OBSL1 | obscurin-like 1 | -0.48 |
| KIAA1958 | KIAA1958 | -0.47 |
| VGLL4 | vestigial-like family member 4 | -0.47 |
| CD58 | CD58 molecule | -0.45 |
| LYSMD2 | LysM, putative peptidoglycan-binding, domain containing 2 | -0.45 |
| TMEM63A | transmembrane protein 63A | -0.43 |
| UCHL5 | ubiquitin carboxyl-terminal hydrolase L5 | -0.43 |
| MYH15 | myosin, heavy chain 15 | -0.42 |
| WRB | tryptophan rich basic protein | -0.4 |
| POMP | proteasome maturation protein | -0.39 |
| YIF1A | Yip1 interacting factor homolog A (S. cerevisiae) | -0.39 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.38 |
| YDJC | YdjC homolog (bacterial) | -0.38 |
| POLR2M | polymerase (RNA) II (DNA directed) polypeptide M | -0.38 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.37 |
| KLC1 | kinesin light chain 1 | -0.36 |
| DDA1 | DET1 and DDB1 associated 1 | -0.36 |
| WDR25 | WD repeat domain 25 | -0.35 |
| C12ORF4 | chromosome 12 open reading frame 4 | -0.35 |
| TRIAP1 | TP53 regulated inhibitor of apoptosis 1 | -0.35 |
| ZNF264 | zinc finger protein 264 | -0.34 |
| EFNB1 | ephrin-B1 | -0.34 |
| RFX7 | regulatory factor X, 7 | -0.34 |
| AGAP3 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 | -0.33 |
| DOLK | dolichol kinase | -0.33 |
| MEX3A | mex-3 RNA binding family member A | -0.33 |
| DERL1 | derlin 1 | -0.32 |
| SLC35B1 | solute carrier family 35, member B1 | -0.32 |
| CNTROB | centrobin, centrosomal BRCA2 interacting protein | -0.32 |
| ERCC8 | excision repair cross-complementation group 8 | -0.32 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C | -0.31 |
| GJC1 | gap junction protein, gamma 1, 45kDa | -0.31 |
| TAF10 | TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa | -0.31 |
| FZD3 | frizzled class receptor 3 | -0.31 |
| TJP3 | tight junction protein 3 | -0.31 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.31 |
| EPHX4 | epoxide hydrolase 4 | -0.31 |
| TUFT1 | tuftelin 1 | -0.3 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.3 |
| KLF10 | Kruppel-like factor 10 | -0.3 |
| OGDHL | oxoglutarate dehydrogenase-like | -0.3 |
| SUMF1 | sulfatase modifying factor 1 | -0.3 |
| MPDU1 | mannose-P-dolichol utilization defect 1 | -0.3 |
| ZNF624 | zinc finger protein 624 | -0.3 |
| LOXL2 | lysyl oxidase-like 2 | -0.3 |
| MED22 | mediator complex subunit 22 | -0.3 |
| SHKBP1 | SH3KBP1 binding protein 1 | -0.3 |
| CENPT | centromere protein T | -0.3 |
| TTN | titin | -0.29 |
| C12ORF66 | chromosome 12 open reading frame 66 | -0.29 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.29 |
| NAAA | N-acylethanolamine acid amidase | -0.29 |
| PPIP5K1 | diphosphoinositol pentakisphosphate kinase 1 | -0.29 |
| HSP90AB4P | heat shock protein 90kDa alpha (cytosolic), class B member 4, pseudogene | -0.28 |
| TMEM222 | transmembrane protein 222 | -0.28 |
| HM13 | histocompatibility (minor) 13 | -0.28 |
| RGL3 | ral guanine nucleotide dissociation stimulator-like 3 | -0.28 |
| ENTPD2 | ectonucleoside triphosphate diphosphohydrolase 2 | -0.28 |
| NOP10 | NOP10 ribonucleoprotein | -0.28 |
| ICAM1 | intercellular adhesion molecule 1 | -0.28 |
| MBLAC2 | metallo-beta-lactamase domain containing 2 | -0.28 |
| KCTD1 | potassium channel tetramerization domain containing 1 | -0.27 |
| PIGX | phosphatidylinositol glycan anchor biosynthesis, class X | -0.27 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.27 |
| SULT1C2 | sulfotransferase family, cytosolic, 1C, member 2 | -0.27 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | -0.27 |
| ZDHHC23 | zinc finger, DHHC-type containing 23 | -0.27 |
| WIPF3 | WAS/WASL interacting protein family, member 3 | -0.27 |
| WASF3 | WAS protein family, member 3 | -0.27 |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) | -0.27 |
| BOLA1 | bolA family member 1 | -0.27 |
| LYPLA2 | lysophospholipase II | -0.27 |
| CCDC90B | coiled-coil domain containing 90B | -0.27 |
| MIIP | migration and invasion inhibitory protein | -0.27 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) | -0.27 |
| BAHCC1 | BAH domain and coiled-coil containing 1 | -0.27 |
| PRMT2IP | PRMT2 interacting protein | -0.26 |
| NEB | nebulin | -0.26 |
| PCNX3 | pecanex 3 | -0.26 |
| PREX1 | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1 | -0.26 |
| COQ2 | coenzyme Q2 4-hydroxybenzoate polyprenyltransferase | -0.26 |
| FN1 | fibronectin 1 | -0.25 |
| SNAPIN | SNAP-associated protein | -0.25 |
| HLA-A | major histocompatibility complex, class I, A | -0.25 |
| UBE2C | ubiquitin-conjugating enzyme E2C | -0.25 |
| PCGF6 | polycomb group ring finger 6 | -0.25 |
| ARSD | arylsulfatase D | -0.25 |
| R3HDM2 | R3H domain containing 2 | -0.25 |
| HMGXB4 | HMG box domain containing 4 | -0.25 |
| ANAPC10 | anaphase promoting complex subunit 10 | -0.24 |
| ALAS1 | 5'-aminolevulinate synthase 1 | -0.24 |
