| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Thymol perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Thymol_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.234996 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.201641 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.18536 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.176189 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.117097 |
| PODXL | podocalyxin-like | 0.110812 |
| FLNB | filamin B, beta | 0.107059 |
| CDH13 | cadherin 13 | 0.0968643 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0957759 |
| VIM | vimentin | 0.0902754 |
| CD44 | CD44 molecule (Indian blood group) | 0.085012 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0781426 |
| EGFR | epidermal growth factor receptor | 0.0760554 |
| RUNX1 | runt-related transcription factor 1 | 0.0739541 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0733799 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0710035 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0653171 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0632295 |
| LOX | lysyl oxidase | 0.058497 |
| SEPTIN9 | septin 9 | 0.0583749 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0583702 |
| TPM3 | tropomyosin 3 | 0.0583327 |
| NDRG1 | N-myc downstream regulated 1 | 0.0563588 |
| EFNA5 | ephrin-A5 | 0.0556426 |
| MYADM | myeloid-associated differentiation marker | 0.0549041 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0526777 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0523112 |
| COL5A1 | collagen, type V, alpha 1 | 0.052038 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0507352 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0483391 |
| FN1 | fibronectin 1 | 0.0481933 |
| DCLK2 | doublecortin-like kinase 2 | 0.0471503 |
| ANXA5 | annexin A5 | 0.0468122 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0464924 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0460624 |
| ZNF292 | zinc finger protein 292 | 0.0457256 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0454716 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0444134 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0433829 |
| CEP170 | centrosomal protein 170kDa | 0.0425906 |
| SYTL3 | synaptotagmin-like 3 | 0.0424795 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0421184 |
| MYOF | myoferlin | 0.0412361 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0411912 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.040907 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0379271 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0379253 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0377327 |
| CD109 | CD109 molecule | 0.0372981 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0367854 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0365361 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0359681 |
| RAI1 | retinoic acid induced 1 | 0.0358687 |
| SMYD3 | SET and MYND domain containing 3 | 0.0358552 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0358547 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0358523 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | 0.0357554 |
| SEPTIN7 | septin 7 | 0.0357285 |
| CD99 | CD99 molecule | 0.0355762 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0350635 |
| DST | dystonin | 0.0350596 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0346732 |
| YEATS2 | YEATS domain containing 2 | 0.0342752 |
| NAV1 | neuron navigator 1 | 0.0340675 |
| SETD5 | SET domain containing 5 | 0.0339426 |
| MB21D2 | Mab-21 domain containing 2 | 0.033792 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0337325 |
| AXL | AXL receptor tyrosine kinase | 0.0321864 |
| USP34 | ubiquitin specific peptidase 34 | 0.0309308 |
| HDAC9 | histone deacetylase 9 | 0.0305514 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0303014 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0301461 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0300273 |
| PKM | pyruvate kinase, muscle | 0.0298943 |
| ZNF148 | zinc finger protein 148 | 0.0298106 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0297927 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0297739 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0295965 |
| S100A10 | S100 calcium binding protein A10 | 0.0293105 |
| MKI67 | marker of proliferation Ki-67 | 0.0290365 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0288083 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0287186 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0284483 |
| PFKP | phosphofructokinase, platelet | 0.0282745 |
| ANXA2 | annexin A2 | 0.02804 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0279714 |
| RTN4 | reticulon 4 | 0.0279606 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0278741 |
| RIPK1 | receptor (TNFRSF)-interacting serine-threonine kinase 1 | 0.0275731 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0272918 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0272859 |
| HELZ | helicase with zinc finger | 0.0271822 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0269829 |
| BCL2L1 | BCL2-like 1 | 0.0268777 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0268699 |
| MSN | moesin | 0.0268242 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0265541 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0265249 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0263838 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.0263757 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.254928 |
| FBN1 | fibrillin 1 | -0.089864 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0692526 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0547435 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0524415 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.049899 |
| AHNAK | AHNAK nucleoprotein | -0.0493417 |
| ACTG1 | actin gamma 1 | -0.0484956 |
| VCL | vinculin | -0.0465454 |
| INTS6 | integrator complex subunit 6 | -0.0461112 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.044035 |
| LMNA | lamin A/C | -0.0423678 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0423174 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0414309 |
| PTMA | prothymosin, alpha | -0.0405552 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0384642 |
| COL1A2 | collagen, type I, alpha 2 | -0.0378895 |
| SQSTM1 | sequestosome 1 | -0.0365512 |
| RPS24 | ribosomal protein S24 | -0.0359539 |
| POTEF | POTE ankyrin domain family, member F | -0.0344805 |
| SP100 | SP100 nuclear antigen | -0.0330027 |
| RPL23 | ribosomal protein L23 | -0.0328934 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0292208 |
| HLA-B | major histocompatibility complex, class I, B | -0.0287846 |
| RPL35A | ribosomal protein L35a | -0.0286286 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0285486 |
| RIGI | RNA sensor RIG-I | -0.0278439 |
| SEC61G | Sec61 gamma subunit | -0.0274227 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0269257 |
| FRMD5 | FERM domain containing 5 | -0.0261834 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0258135 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0252723 |
| RPL28 | ribosomal protein L28 | -0.0252042 |
| COL5A2 | collagen, type V, alpha 2 | -0.0251371 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0244352 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0233353 |
| HLA-C | major histocompatibility complex, class I, C | -0.0230611 |
| UBC | ubiquitin C | -0.0224587 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0222714 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0222701 |
| CAVIN1 | caveolae associated protein 1 | -0.0221454 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0218801 |
| RPL19 | ribosomal protein L19 | -0.021759 |
| RPS19 | ribosomal protein S19 | -0.0215391 |
| COL1A1 | collagen, type I, alpha 1 | -0.0213833 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0209746 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.020453 |
| RPS27A | ribosomal protein S27a | -0.0203969 |
| CD81 | CD81 molecule | -0.0199563 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0198254 |
| RPL9 | ribosomal protein L9 | -0.019735 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0195153 |
| JAZF1 | JAZF zinc finger 1 | -0.0194068 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0189249 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0182253 |
| GPC6 | glypican 6 | -0.0181766 |
| RPL34 | ribosomal protein L34 | -0.0181101 |
| MX2 | MX dynamin-like GTPase 2 | -0.0178944 |
| RPS8 | ribosomal protein S8 | -0.0177609 |
| AEBP2 | AE binding protein 2 | -0.0177577 |
| RPS21 | ribosomal protein S21 | -0.0176326 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0176299 |
| RPL11 | ribosomal protein L11 | -0.0175552 |
| FBXO11 | F-box protein 11 | -0.0173659 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0173292 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0173126 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0172972 |
| MT1X | metallothionein 1X | -0.0172878 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0172615 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0171764 |
| RPS3 | ribosomal protein S3 | -0.017119 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0170542 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0170174 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0168657 |
| RPL26 | ribosomal protein L26 | -0.0167333 |
| RPL32 | ribosomal protein L32 | -0.0167284 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0163195 |
| CUX1 | cut-like homeobox 1 | -0.0162976 |
| TMEM263 | transmembrane protein 263 | -0.0162076 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0158765 |
| RPS11 | ribosomal protein S11 | -0.0156912 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0154715 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0153755 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0153364 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0153059 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0152919 |
| KRT81 | keratin 81, type II | -0.015227 |
| FUS | FUS RNA binding protein | -0.0150925 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | -0.0150839 |
| WTAP | Wilms tumor 1 associated protein | -0.0150083 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0150082 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0149809 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0149372 |
| NLK | nemo-like kinase | -0.0148914 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | -0.0147677 |
| MT2A | metallothionein 2A | -0.0147654 |
| EDF1 | endothelial differentiation-related factor 1 | -0.0147251 |
| FTL | ferritin, light polypeptide | -0.0145507 |
| RPS14 | ribosomal protein S14 | -0.0145228 |
| RPL31 | ribosomal protein L31 | -0.014436 |
