| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Thymol perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Thymol_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.136679 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.127966 |
| AREG | amphiregulin | 0.119244 |
| VMP1 | vacuole membrane protein 1 | 0.118207 |
| TMEM41B | transmembrane protein 41B | 0.117044 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.116796 |
| JMJD1C | jumonji domain containing 1C | 0.102866 |
| MMP12 | matrix metallopeptidase 12 | 0.0996181 |
| ANXA1 | annexin A1 | 0.0976273 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0905946 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | 0.0653451 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0649802 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.063485 |
| TXNRD1 | thioredoxin reductase 1 | 0.0621771 |
| RTN4 | reticulon 4 | 0.0616682 |
| ATP11A | ATPase, class VI, type 11A | 0.0553252 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0539595 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0538918 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0522686 |
| XPO1 | exportin 1 | 0.0502471 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0497173 |
| PDGFC | platelet derived growth factor C | 0.0492381 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0490019 |
| USP34 | ubiquitin specific peptidase 34 | 0.0465982 |
| TPM3 | tropomyosin 3 | 0.045022 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0442455 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0441345 |
| RPS12 | ribosomal protein S12 | 0.0438743 |
| EDARADD | EDAR-associated death domain | 0.0433595 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0419749 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0416219 |
| YAP1 | Yes-associated protein 1 | 0.0412935 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0392302 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0388811 |
| NEBL | nebulette | 0.0388754 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0378156 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.035623 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0349879 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0344311 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0341915 |
| CARD16 | caspase recruitment domain family, member 16 | 0.033322 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0332918 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0331961 |
| PCDH9 | protocadherin 9 | 0.032039 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0320263 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0317549 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0311716 |
| FBXO11 | F-box protein 11 | 0.0309237 |
| ANXA5 | annexin A5 | 0.0306194 |
| PHF21A | PHD finger protein 21A | 0.0305242 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0299275 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0298788 |
| ERBIN | erbb2 interacting protein | 0.0295436 |
| OSMR | oncostatin M receptor | 0.0286595 |
| PRKCI | protein kinase C, iota | 0.0284462 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.028294 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0280801 |
| SBF2 | SET binding factor 2 | 0.0272169 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0264441 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.0264209 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0260978 |
| RAB6A | RAB6A, member RAS oncogene family | 0.025824 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0257659 |
| TJP1 | tight junction protein 1 | 0.0248624 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | 0.0247793 |
| WWOX | WW domain containing oxidoreductase | 0.0246012 |
| EZR | ezrin | 0.0245584 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.024224 |
| RPS2 | ribosomal protein S2 | 0.0240127 |
| TBK1 | TANK-binding kinase 1 | 0.0238044 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0237998 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0237816 |
| NIBAN1 | niban apoptosis regulator 1 | 0.023743 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0237101 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0236619 |
| EXOC6B | exocyst complex component 6B | 0.023656 |
| TNPO1 | transportin 1 | 0.023341 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0233368 |
| SESN2 | sestrin 2 | 0.0232875 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0230752 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0229745 |
| CDC42SE2 | CDC42 small effector 2 | 0.0229067 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0228927 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0227367 |
| XPOT | exportin, tRNA | 0.0226813 |
| EHBP1 | EH domain binding protein 1 | 0.0224722 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0224687 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0223653 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0220988 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0218835 |
| HIPK3 | homeodomain interacting protein kinase 3 | 0.0218379 |
| TUBB6 | tubulin, beta 6 class V | 0.0217413 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0216857 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | 0.0215736 |
| NUP58 | nucleoporin 58 | 0.0215424 |
| KIF18B | kinesin family member 18B | 0.0215412 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0214937 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0213265 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0212057 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0211339 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.234617 |
| MYL12B | myosin, light chain 12B, regulatory | -0.101175 |
| ACTG1 | actin gamma 1 | -0.0995379 |
| PTMA | prothymosin, alpha | -0.0910687 |
| RPL35A | ribosomal protein L35a | -0.0855819 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0777326 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0723827 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0693671 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0670515 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0657209 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0570436 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0534855 |
| RPS24 | ribosomal protein S24 | -0.0498831 |
| AHNAK | AHNAK nucleoprotein | -0.0491789 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0458543 |
| RPS21 | ribosomal protein S21 | -0.0451794 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0440517 |
| ADIPOR2 | adiponectin receptor 2 | -0.0432423 |
| RPS19 | ribosomal protein S19 | -0.0429256 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0424827 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0418568 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.041568 |
| RPL23 | ribosomal protein L23 | -0.0409298 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0395421 |
| H1-0 | H1.0 linker histone | -0.038249 |
| RPL34 | ribosomal protein L34 | -0.0359472 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0342242 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0342047 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0335888 |
| CENPF | centromere protein F, 350/400kDa | -0.0335377 |
| RPL19 | ribosomal protein L19 | -0.033396 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.0328006 |
| RPL11 | ribosomal protein L11 | -0.0327175 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0323838 |
| EGR1 | early growth response 1 | -0.0323833 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | -0.0322407 |
| GNAS | GNAS complex locus | -0.0311588 |
| RPS14 | ribosomal protein S14 | -0.0309969 |
| PTMS | parathymosin | -0.0304987 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.0303295 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0295392 |
| HMGA2 | high mobility group AT-hook 2 | -0.0294675 |
| RPLP0 | ribosomal protein, large, P0 | -0.0289691 |
| RPS27A | ribosomal protein S27a | -0.0287717 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0286829 |
| LMO7 | LIM domain 7 | -0.0286068 |
| INTS6 | integrator complex subunit 6 | -0.0274864 |
| ECT2 | epithelial cell transforming 2 | -0.0271919 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0271562 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0267365 |
| KHSRP | KH-type splicing regulatory protein | -0.0265305 |
| DST | dystonin | -0.0265179 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0264212 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | -0.0258391 |
| RPL12 | ribosomal protein L12 | -0.0254888 |
| HMGB1 | high mobility group box 1 | -0.0251468 |
| RPLP1 | ribosomal protein, large, P1 | -0.0250538 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0242693 |
| RPL9 | ribosomal protein L9 | -0.0239621 |
| YBX1 | Y box binding protein 1 | -0.0239132 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.023843 |
| CANX | calnexin | -0.0236499 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0233801 |
| LARP4B | La ribonucleoprotein domain family, member 4B | -0.0231496 |
| RPS4X | ribosomal protein S4, X-linked | -0.0231353 |
| CCDC47 | coiled-coil domain containing 47 | -0.0230889 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0230838 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0230141 |
| TUBA1B | tubulin, alpha 1b | -0.0228164 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0227844 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | -0.0224468 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0223885 |
| RPL32 | ribosomal protein L32 | -0.0223803 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0223635 |
| RPS9 | ribosomal protein S9 | -0.021633 |
| RPS5 | ribosomal protein S5 | -0.0216308 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0216029 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0215459 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.021344 |
| CLPTM1L | CLPTM1-like | -0.0213023 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0211884 |
| RPL8 | ribosomal protein L8 | -0.0210358 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.0208745 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0205197 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0204633 |
| CDV3 | CDV3 homolog (mouse) | -0.0202897 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0200135 |
| LRRC23 | leucine rich repeat containing 23 | -0.0199712 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0198814 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0195133 |
| TCP1 | t-complex 1 | -0.0192729 |
| RPL38 | ribosomal protein L38 | -0.0192571 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0192281 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0190276 |
| TUBB | tubulin, beta class I | -0.0188986 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.0188335 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0187953 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | -0.0187877 |
| POU2F1 | POU class 2 homeobox 1 | -0.0187581 |
| AXIN2 | axin 2 | -0.0187237 |