| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Thymol perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Thymol_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.171062 |
| RPS6 | ribosomal protein S6 | 0.153422 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.116395 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.102621 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0965099 |
| VEGFA | vascular endothelial growth factor A | 0.0839508 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0772569 |
| TXNIP | thioredoxin interacting protein | 0.0771165 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0631639 |
| LDHA | lactate dehydrogenase A | 0.059519 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0582997 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0578857 |
| MYO1E | myosin IE | 0.0570605 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0564271 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0559478 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0547295 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0542982 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0537562 |
| FAT1 | FAT atypical cadherin 1 | 0.052922 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0525577 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0517652 |
| ENO1 | enolase 1, (alpha) | 0.0516568 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.051266 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0504073 |
| PKM | pyruvate kinase, muscle | 0.0503667 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0494476 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | 0.0490555 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.048918 |
| NEBL | nebulette | 0.0482364 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.0480688 |
| RREB1 | ras responsive element binding protein 1 | 0.0463742 |
| EGFR | epidermal growth factor receptor | 0.0451345 |
| NDRG1 | N-myc downstream regulated 1 | 0.0446858 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0445376 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0435235 |
| CALR | calreticulin | 0.0435065 |
| DNM2 | dynamin 2 | 0.0419268 |
| GLG1 | golgi glycoprotein 1 | 0.040968 |
| FTL | ferritin, light polypeptide | 0.0407961 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0403376 |
| ZNF292 | zinc finger protein 292 | 0.0402134 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0395865 |
| HMGA1 | high mobility group AT-hook 1 | 0.0389837 |
| LMO7 | LIM domain 7 | 0.0385622 |
| SNX9 | sorting nexin 9 | 0.0383828 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0370685 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0370476 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0361865 |
| KIF5B | kinesin family member 5B | 0.035711 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0348636 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | 0.0347854 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0337281 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0333345 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0332593 |
| PARD3B | par-3 family cell polarity regulator beta | 0.03312 |
| TPM4 | tropomyosin 4 | 0.0329366 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | 0.0321086 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.031997 |
| GOLGB1 | golgin B1 | 0.0318923 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0316623 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0309773 |
| GOLGA4 | golgin A4 | 0.0309641 |
| RPS6KA5 | ribosomal protein S6 kinase, 90kDa, polypeptide 5 | 0.0308602 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0307392 |
| PLS1 | plastin 1 | 0.030119 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0299797 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0298971 |
| ARFGEF3 | ARFGEF family member 3 | 0.0296508 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0296223 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.029244 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0291304 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | 0.0289269 |
| TPM3 | tropomyosin 3 | 0.0287097 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0286832 |
| SSR1 | signal sequence receptor, alpha | 0.0283812 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0282784 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.0281934 |
| CDK13 | cyclin-dependent kinase 13 | 0.0279543 |
| DSPP | dentin sialophosphoprotein | 0.0276114 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | 0.0275581 |
| ABHD2 | abhydrolase domain containing 2 | 0.0275454 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0275329 |
| PTEN | phosphatase and tensin homolog | 0.0275243 |
| RPS2 | ribosomal protein S2 | 0.0274503 |
| CCSER1 | coiled-coil serine-rich protein 1 | 0.0274391 |
| MLEC | malectin | 0.0274233 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0273289 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0272976 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.0270407 |
| SAMD5 | sterile alpha motif domain containing 5 | 0.0269546 |
| VCAN | versican | 0.0268809 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0267066 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.0264536 |
| ATXN1 | ataxin 1 | 0.0262016 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0257598 |
| JAK1 | Janus kinase 1 | 0.0256029 |
| SLK | STE20-like kinase | 0.025468 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0254641 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0254338 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0252039 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.173261 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.127798 |
| VCL | vinculin | -0.0896389 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0871352 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0759393 |
| NPSR1 | neuropeptide S receptor 1 | -0.0732208 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0687105 |
| ACTN4 | actinin, alpha 4 | -0.0578062 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0578014 |
| RPS24 | ribosomal protein S24 | -0.0533386 |
| RPS21 | ribosomal protein S21 | -0.0507923 |
| ACTG1 | actin gamma 1 | -0.0428936 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0415143 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0414803 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0404208 |
| IER3 | immediate early response 3 | -0.0379451 |
| RPL36 | ribosomal protein L36 | -0.0375625 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0353417 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0312503 |
| PCDHB16 | protocadherin beta 16 | -0.0310957 |
| SPON1 | spondin 1, extracellular matrix protein | -0.0302531 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0284867 |
| RPL32 | ribosomal protein L32 | -0.0277236 |
| RBM39 | RNA binding motif protein 39 | -0.0276792 |
| TMEM135 | transmembrane protein 135 | -0.027346 |
| S100P | S100 calcium binding protein P | -0.0266281 |
| NRN1 | neuritin 1 | -0.0260646 |
| GPHN | gephyrin | -0.0258053 |
| WDR1 | WD repeat domain 1 | -0.025666 |
| FRMD5 | FERM domain containing 5 | -0.0253892 |
| RPLP2 | ribosomal protein, large, P2 | -0.0250489 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0247772 |
| S100A9 | S100 calcium binding protein A9 | -0.0245989 |
| LAMB3 | laminin, beta 3 | -0.0241073 |
| RPS27A | ribosomal protein S27a | -0.0239739 |
| LAMA4 | laminin, alpha 4 | -0.0237304 |
| RPS3 | ribosomal protein S3 | -0.0235315 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0231375 |
| RPS11 | ribosomal protein S11 | -0.0229722 |
| KITLG | KIT ligand | -0.0227946 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0225697 |
| RPL36AL | ribosomal protein L36a-like | -0.0221824 |
| PIGR | polymeric immunoglobulin receptor | -0.0219954 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0219547 |
| DERA | deoxyribose-phosphate aldolase (putative) | -0.0219316 |
| WWC1 | WW and C2 domain containing 1 | -0.021869 |
| KRT18 | keratin 18, type I | -0.0218002 |
| AHNAK | AHNAK nucleoprotein | -0.0217576 |
| ANXA2 | annexin A2 | -0.0217191 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0217067 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0214421 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | -0.0214237 |
| TFF1 | trefoil factor 1 | -0.0213991 |
| KRT8 | keratin 8, type II | -0.0213866 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | -0.0211772 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0211548 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0210309 |
| SHROOM3 | shroom family member 3 | -0.0208228 |
| MYO1D | myosin ID | -0.0208128 |
| STT3B | STT3B, subunit of the oligosaccharyltransferase complex (catalytic) | -0.0208041 |
| RPL9 | ribosomal protein L9 | -0.0203707 |
| INSIG1 | insulin induced gene 1 | -0.0203564 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.020262 |
| S100A14 | S100 calcium binding protein A14 | -0.0201871 |
| TFRC | transferrin receptor | -0.0201035 |
| RPL26 | ribosomal protein L26 | -0.0200582 |
| CACNB2 | calcium channel, voltage-dependent, beta 2 subunit | -0.019567 |
| RRBP1 | ribosome binding protein 1 | -0.0194474 |
| ATF4 | activating transcription factor 4 | -0.0191723 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0191346 |
| EWSR1 | EWS RNA-binding protein 1 | -0.0189174 |
| RBM26 | RNA binding motif protein 26 | -0.0188963 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.0186494 |
| RBBP6 | retinoblastoma binding protein 6 | -0.0186218 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0184953 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | -0.0183779 |
| LMNA | lamin A/C | -0.0183556 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0180846 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | -0.0180223 |
| ETV6 | ets variant 6 | -0.0178952 |
| PGK1 | phosphoglycerate kinase 1 | -0.0178619 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0178301 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0175666 |
| MYOF | myoferlin | -0.0174142 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0172707 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0172416 |
| EMP1 | epithelial membrane protein 1 | -0.0171557 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0171296 |
| GANAB | glucosidase, alpha; neutral AB | -0.0169621 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | -0.016896 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0166828 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0166692 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0166417 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0166179 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.0165778 |
| VWA8 | von Willebrand factor A domain containing 8 | -0.0165149 |
| CDK6 | cyclin-dependent kinase 6 | -0.0164181 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0164005 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | -0.0163391 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | -0.0163361 |
