| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Thymol perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Thymol_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.179194 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.151983 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.123789 |
| CAPRIN2 | caprin family member 2 | 0.120047 |
| DST | dystonin | 0.117148 |
| TP63 | tumor protein p63 | 0.0985733 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0752317 |
| FTL | ferritin, light polypeptide | 0.0653874 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0647724 |
| HMGA1 | high mobility group AT-hook 1 | 0.0636401 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0613722 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0610492 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0587904 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0554974 |
| TXNIP | thioredoxin interacting protein | 0.0554743 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | 0.0548784 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.053214 |
| PDE10A | phosphodiesterase 10A | 0.0525573 |
| PRELID2 | PRELI domain containing 2 | 0.0506109 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0499924 |
| CADM2 | cell adhesion molecule 2 | 0.0489733 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0486244 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0486201 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0476373 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0468711 |
| DNER | delta/notch-like EGF repeat containing | 0.0450548 |
| RPS6 | ribosomal protein S6 | 0.0442241 |
| VMP1 | vacuole membrane protein 1 | 0.0439322 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0436928 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.043336 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | 0.0425552 |
| ANGPTL4 | angiopoietin-like 4 | 0.0425102 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0422024 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0415629 |
| FMNL2 | formin-like 2 | 0.0405517 |
| NDRG1 | N-myc downstream regulated 1 | 0.0371608 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0370492 |
| TRIM56 | tripartite motif containing 56 | 0.0366808 |
| F2R | coagulation factor II (thrombin) receptor | 0.0360559 |
| HLA-B | major histocompatibility complex, class I, B | 0.0357215 |
| DPYD | dihydropyrimidine dehydrogenase | 0.035265 |
| DPH6 | diphthamine biosynthesis 6 | 0.0346337 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0336081 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0332529 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0331418 |
| ENO1 | enolase 1, (alpha) | 0.0328421 |
| RPS27 | ribosomal protein S27 | 0.0320983 |
| RAD51B | RAD51 paralog B | 0.0319913 |
| ZNF292 | zinc finger protein 292 | 0.0318554 |
| RPS12 | ribosomal protein S12 | 0.0315798 |
| BBX | bobby sox homolog (Drosophila) | 0.0315262 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0314886 |
| MEF2A | myocyte enhancer factor 2A | 0.0312375 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0312236 |
| GYS1 | glycogen synthase 1 (muscle) | 0.030966 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0309275 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0308004 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0306593 |
| SUMF1 | sulfatase modifying factor 1 | 0.0306268 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0302141 |
| PRKCE | protein kinase C, epsilon | 0.0299273 |
| CSMD3 | CUB and Sushi multiple domains 3 | 0.0298879 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.029343 |
| ARFGEF3 | ARFGEF family member 3 | 0.0282296 |
| VEGFA | vascular endothelial growth factor A | 0.0282026 |
| RIOK3 | RIO kinase 3 | 0.0280142 |
| MT1E | metallothionein 1E | 0.0277367 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0276905 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0275055 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.027476 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0269734 |
| RPL31 | ribosomal protein L31 | 0.0266951 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0266258 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0261285 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0256916 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0255256 |
| EGFR | epidermal growth factor receptor | 0.0255179 |
| ANK2 | ankyrin 2, neuronal | 0.0249227 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.024842 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0247391 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0245455 |
| SEC24A | SEC24 family member A | 0.0245313 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit | 0.0245273 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0245103 |
| PLK2 | polo-like kinase 2 | 0.024352 |
| JMJD1C | jumonji domain containing 1C | 0.0243381 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.0243015 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0243002 |
| AREG | amphiregulin | 0.0240626 |
| RPL39 | ribosomal protein L39 | 0.0239782 |
| S100A6 | S100 calcium binding protein A6 | 0.0239075 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0238569 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0237215 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0236615 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0236025 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0235432 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0229698 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0228331 |
| JAK1 | Janus kinase 1 | 0.0226493 |
| GCLM | glutamate-cysteine ligase, modifier subunit | 0.0226201 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.207079 |
| VIM | vimentin | -0.157294 |
| TMSB10 | thymosin beta 10 | -0.13218 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.113267 |
| TMSB4X | thymosin beta 4, X-linked | -0.107979 |
| AHNAK | AHNAK nucleoprotein | -0.105259 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0962973 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.094502 |
| CENPF | centromere protein F, 350/400kDa | -0.0927166 |
| PTMA | prothymosin, alpha | -0.082408 |
| TXNRD1 | thioredoxin reductase 1 | -0.0822276 |
| RAI1 | retinoic acid induced 1 | -0.0795565 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0776521 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0770038 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0731082 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0653935 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0641503 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0604684 |
| ACTG1 | actin gamma 1 | -0.0600539 |
| CANX | calnexin | -0.0582733 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0538127 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.051507 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0508525 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0496643 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0485988 |
| RTN4 | reticulon 4 | -0.0459228 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0451797 |
| SRGN | serglycin | -0.0447774 |
| ANLN | anillin, actin binding protein | -0.0445552 |
| ECT2 | epithelial cell transforming 2 | -0.0442733 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0438215 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0434589 |
| MKI67 | marker of proliferation Ki-67 | -0.0430627 |
| PGK1 | phosphoglycerate kinase 1 | -0.0426724 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0419699 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0404911 |
| RPS24 | ribosomal protein S24 | -0.0388963 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.038063 |
| APP | amyloid beta (A4) precursor protein | -0.0377945 |
| CSDE1 | cold shock domain containing E1, RNA-binding | -0.0377352 |
| RPL23 | ribosomal protein L23 | -0.0376685 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0375017 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0371509 |
| KIF14 | kinesin family member 14 | -0.0362849 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | -0.0361986 |
| ANXA1 | annexin A1 | -0.0350899 |
| CMIP | c-Maf inducing protein | -0.0349765 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0341027 |
| CAPRIN1 | cell cycle associated protein 1 | -0.0339957 |
| RRM2 | ribonucleotide reductase M2 | -0.0339636 |
| DIAPH3 | diaphanous-related formin 3 | -0.0339287 |
| TNPO1 | transportin 1 | -0.0338469 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0337128 |
| HDLBP | high density lipoprotein binding protein | -0.0327904 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0326705 |
| HMGB2 | high mobility group box 2 | -0.0323518 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0321027 |
| EZH2 | enhancer of zeste 2 polycomb repressive complex 2 subunit | -0.0318574 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0310512 |
| HJURP | Holliday junction recognition protein | -0.031 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.030751 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0306527 |
| RPLP0 | ribosomal protein, large, P0 | -0.0305551 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0297786 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0294762 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0293464 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0289731 |
| ZNF217 | zinc finger protein 217 | -0.0289313 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0289024 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0286544 |
| SGO2 | shugoshin 2 | -0.0285366 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0284241 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0282165 |
| SET | SET nuclear proto-oncogene | -0.0281899 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0280694 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0276538 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0275044 |
| CUL1 | cullin 1 | -0.0273788 |
| CEP170 | centrosomal protein 170kDa | -0.0269544 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0269351 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0261508 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0261449 |
| FUS | FUS RNA binding protein | -0.0259286 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0257914 |
| YBX1 | Y box binding protein 1 | -0.0254456 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0253693 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.025123 |
| ARHGAP29 | Rho GTPase activating protein 29 | -0.0250869 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0250089 |
| PTPN11 | protein tyrosine phosphatase, non-receptor type 11 | -0.0249764 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0248068 |
| RLIM | ring finger protein, LIM domain interacting | -0.0247489 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0246261 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0245973 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0245531 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0244929 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0243328 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.0240197 |
| MIB1 | mindbomb E3 ubiquitin protein ligase 1 | -0.0237892 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0236724 |
