| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Thymol perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Thymol_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.271162 |
| FN1 | fibronectin 1 | 0.170998 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.101126 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0953021 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0928259 |
| STC1 | stanniocalcin 1 | 0.081869 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0802928 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0747257 |
| VIM | vimentin | 0.0737025 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0718104 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0715374 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0710605 |
| MAP7 | microtubule-associated protein 7 | 0.0700732 |
| FMNL2 | formin-like 2 | 0.0695913 |
| CHL1 | cell adhesion molecule L1-like | 0.060308 |
| KYNU | kynureninase | 0.0582663 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.057708 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0532142 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0525333 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0492732 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0489651 |
| PM20D1 | peptidase M20 domain containing 1 | 0.0486778 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0481818 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0468836 |
| SMAD2 | SMAD family member 2 | 0.046299 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0456734 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0442247 |
| SPAG9 | sperm associated antigen 9 | 0.0430662 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0428521 |
| INHBA | inhibin, beta A | 0.0424867 |
| IL6 | interleukin 6 | 0.0421215 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0418693 |
| AUTS2 | autism susceptibility candidate 2 | 0.0415326 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0413515 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.041014 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0400819 |
| PYGL | phosphorylase, glycogen, liver | 0.0399185 |
| MCL1 | myeloid cell leukemia 1 | 0.0392441 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 | 0.036889 |
| NBEAL1 | neurobeachin-like 1 | 0.0353342 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0342724 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0341252 |
| GDA | guanine deaminase | 0.0332792 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0331002 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0330549 |
| CDH13 | cadherin 13 | 0.0326969 |
| RPS6 | ribosomal protein S6 | 0.0321547 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | 0.0319887 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0317076 |
| BMERB1 | bMERB domain containing 1 | 0.0316745 |
| BMP6 | bone morphogenetic protein 6 | 0.0311302 |
| OXSR1 | oxidative stress responsive 1 | 0.0310541 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0308796 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0307675 |
| COL4A5 | collagen, type IV, alpha 5 | 0.0305397 |
| CTBP2 | C-terminal binding protein 2 | 0.0299672 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.029962 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0298393 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.029697 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0296394 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.029565 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0294178 |
| NFX1 | nuclear transcription factor, X-box binding 1 | 0.0291667 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | 0.029006 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0288616 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0287985 |
| PRICKLE1 | prickle homolog 1 (Drosophila) | 0.0285311 |
| AGTPBP1 | ATP/GTP binding protein 1 | 0.0283714 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | 0.0283198 |
| DNER | delta/notch-like EGF repeat containing | 0.0282893 |
| CUX1 | cut-like homeobox 1 | 0.0282529 |
| COL4A6 | collagen, type IV, alpha 6 | 0.028216 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.027746 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0272926 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0272339 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0269963 |
| RAB31 | RAB31, member RAS oncogene family | 0.0265807 |
| CD44 | CD44 molecule (Indian blood group) | 0.0264489 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0264434 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0263556 |
| NTN4 | netrin 4 | 0.026335 |
| DOCK5 | dedicator of cytokinesis 5 | 0.026308 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.025857 |
| FAM107B | family with sequence similarity 107, member B | 0.0256495 |
| ABLIM1 | actin binding LIM protein 1 | 0.0252146 |
| XYLT1 | xylosyltransferase I | 0.0250511 |
| CTSL | cathepsin L | 0.0249987 |
| RAB3B | RAB3B, member RAS oncogene family | 0.0249689 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0245586 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0245091 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0244452 |
| UNC5D | unc-5 homolog D (C. elegans) | 0.0239019 |
| COPA | coatomer protein complex, subunit alpha | 0.0237924 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0237849 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0237168 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0234646 |
| FLNB | filamin B, beta | 0.0233246 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0233119 |
| CLMP | CXADR-like membrane protein | 0.0230879 |
| TENM3 | teneurin transmembrane protein 3 | 0.0228678 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | -0.137676 |
| TMSB10 | thymosin beta 10 | -0.0912484 |
| TXNRD1 | thioredoxin reductase 1 | -0.0885577 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0866269 |
| NRCAM | neuronal cell adhesion molecule | -0.0722449 |
| EFNA5 | ephrin-A5 | -0.0674473 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0517448 |
| RPS24 | ribosomal protein S24 | -0.0508154 |
| TNPO1 | transportin 1 | -0.0467985 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0399571 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0378991 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0358859 |
| RPL9 | ribosomal protein L9 | -0.0354207 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0350213 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0348321 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.03463 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0338051 |
| SMYD3 | SET and MYND domain containing 3 | -0.0329817 |
| ACTG1 | actin gamma 1 | -0.031831 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0304539 |
| CENPF | centromere protein F, 350/400kDa | -0.0301339 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0300169 |
| RPL23 | ribosomal protein L23 | -0.0293004 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0292712 |
| RPS21 | ribosomal protein S21 | -0.0287385 |
| MYOF | myoferlin | -0.0286172 |
| SRGN | serglycin | -0.0286015 |
| DIAPH3 | diaphanous-related formin 3 | -0.0276708 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0270266 |
| ABCC2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 2 | -0.0270176 |
| PRDX1 | peroxiredoxin 1 | -0.0259494 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0258186 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0256231 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.024968 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0249165 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | -0.0243697 |
| RPS4X | ribosomal protein S4, X-linked | -0.0242692 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0241379 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0241179 |
| RBM39 | RNA binding motif protein 39 | -0.0234602 |
| FUS | FUS RNA binding protein | -0.0231829 |
| RPL35A | ribosomal protein L35a | -0.0223342 |
| ANLN | anillin, actin binding protein | -0.0221804 |
| AHNAK | AHNAK nucleoprotein | -0.02179 |
| MT2A | metallothionein 2A | -0.0211766 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0206899 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0203412 |
| NEK7 | NIMA-related kinase 7 | -0.0199387 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0195259 |
| EXO1 | exonuclease 1 | -0.019197 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0191864 |
| RPL26 | ribosomal protein L26 | -0.0189861 |
| RRBP1 | ribosome binding protein 1 | -0.0189347 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0188665 |
| CENPE | centromere protein E, 312kDa | -0.0184883 |
| SLC25A3 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | -0.0183096 |
| OGA | O-GlcNAcase | -0.0182434 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0180177 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0179271 |
| SEPTIN10 | septin 10 | -0.0178804 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0176883 |
| RPL11 | ribosomal protein L11 | -0.0176083 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0175951 |
| PALLD | palladin, cytoskeletal associated protein | -0.0172586 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.01719 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0167615 |
| PGK1 | phosphoglycerate kinase 1 | -0.0167094 |
| WDFY2 | WD repeat and FYVE domain containing 2 | -0.0166663 |
| RPS27A | ribosomal protein S27a | -0.0164437 |
| NFIA | nuclear factor I/A | -0.0162935 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.016292 |
| PIR | pirin (iron-binding nuclear protein) | -0.016129 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0160212 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.016006 |
| TUSC3 | tumor suppressor candidate 3 | -0.0158793 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0158288 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0157869 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0154978 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0154825 |
| MAP1B | microtubule-associated protein 1B | -0.0152056 |
| RBM25 | RNA binding motif protein 25 | -0.0150468 |
| RPLP0 | ribosomal protein, large, P0 | -0.0150282 |
| PCBP3 | poly(rC) binding protein 3 | -0.0150016 |
| ATP5F1E | ATP synthase F1 subunit epsilon | -0.0149724 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0147619 |
| SP3 | Sp3 transcription factor | -0.0147613 |
| SKP1 | S-phase kinase-associated protein 1 | -0.0147189 |
| THOC2 | THO complex 2 | -0.0146829 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | -0.0146592 |
| IFRD1 | interferon-related developmental regulator 1 | -0.014601 |
| PTGR1 | prostaglandin reductase 1 | -0.0145565 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0145348 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0145004 |
| PCNX1 | pecanex 1 | -0.0144325 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | -0.0143083 |
| METTL15 | methyltransferase like 15 | -0.0142439 |
| CANX | calnexin | -0.0141685 |
| RPL38 | ribosomal protein L38 | -0.0140903 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0140586 |
| SHTN1 | shootin 1 | -0.0139836 |
