Thymol_NCI-H596 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Thymol perturbation in NCI-H596 cell line (Tahoe Therapeutics)
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Genes

70 genes differentially expressed following the Thymol_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 0.203614
PRRC2C proline-rich coiled-coil 2C 0.163542
PRELID2 PRELI domain containing 2 0.131327
MBNL1 muscleblind-like splicing regulator 1 0.122758
FMN1 formin 1 0.120732
PRKCE protein kinase C, epsilon 0.106192
CALD1 caldesmon 1 0.105992
RUNX1 runt-related transcription factor 1 0.105278
EXOC6B exocyst complex component 6B 0.103395
BIRC6 baculoviral IAP repeat containing 6 0.101085
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.1007
ITPRID2 ITPR interacting domain containing 2 0.0968725
PRKG1 protein kinase, cGMP-dependent, type I 0.0909159
MSI2 musashi RNA-binding protein 2 0.0883446
DCBLD2 discoidin, CUB and LCCL domain containing 2 0.0868571
HMGA2 high mobility group AT-hook 2 0.0863669
VIM vimentin 0.0849703
FMNL2 formin-like 2 0.0847197
DTNA dystrobrevin, alpha 0.0846786
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 0.0798475
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0736699
ZMYND8 zinc finger, MYND-type containing 8 0.0659016
STAT1 signal transducer and activator of transcription 1, 91kDa 0.0559649
EXT1 exostosin glycosyltransferase 1 0.0481644
DSCAM Down syndrome cell adhesion molecule 0.0388167
FNDC3B fibronectin type III domain containing 3B 0.0322872
PRKCA protein kinase C, alpha 0.0306319
LPP LIM domain containing preferred translocation partner in lipoma 0.0238999
TRIO trio Rho guanine nucleotide exchange factor 0.0159818
ASPH aspartate beta-hydroxylase 0.014149
GPC6 glypican 6 0.00799068

decreased expression

Symbol Name Standardized Value
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) -0.190759
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.157421
FN1 fibronectin 1 -0.149184
IGF2 insulin-like growth factor 2 -0.125519
COL5A2 collagen, type V, alpha 2 -0.119131
ZBTB20 zinc finger and BTB domain containing 20 -0.0999897
ERO1A endoplasmic reticulum oxidoreductase 1 alpha -0.0950728
EGFR epidermal growth factor receptor -0.0926716
LDHA lactate dehydrogenase A -0.0925874
UBC ubiquitin C -0.0911239
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0906109
RIGI RNA sensor RIG-I -0.0882054
ANXA2 annexin A2 -0.0841868
PDE4D phosphodiesterase 4D, cAMP-specific -0.0798887
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) -0.0785426
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.0730811
TMSB10 thymosin beta 10 -0.0592355
NKD1 naked cuticle homolog 1 (Drosophila) -0.0574534
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0572855
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0538416
RPL23 ribosomal protein L23 -0.0529249
NDRG1 N-myc downstream regulated 1 -0.0528592
MYO1E myosin IE -0.0514379
GNPDA1 glucosamine-6-phosphate deaminase 1 -0.0438095
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type -0.0437467
PGK1 phosphoglycerate kinase 1 -0.0425864
RPL35A ribosomal protein L35a -0.0425841
PTMA prothymosin, alpha -0.0403913
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0384152
JMJD1C jumonji domain containing 1C -0.0349193
RPS3 ribosomal protein S3 -0.0320493
RTN4 reticulon 4 -0.0298761
AKAP12 A kinase (PRKA) anchor protein 12 -0.0183312
FLNB filamin B, beta -0.0178658
ACTG1 actin gamma 1 -0.0168838
SBF2 SET binding factor 2 -0.0136517
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.012153
DST dystonin -0.00494144
RPS6 ribosomal protein S6 -0.00222185