Thymol_SW 1271 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Thymol perturbation in SW 1271 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Thymol_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
FNDC3B fibronectin type III domain containing 3B 0.235572
IGFBP3 insulin-like growth factor binding protein 3 0.0957563
SVIL supervillin 0.0860308
PRKCA protein kinase C, alpha 0.0817712
SH3KBP1 SH3-domain kinase binding protein 1 0.0802671
CD44 CD44 molecule (Indian blood group) 0.0737972
FMNL2 formin-like 2 0.0732535
ZBTB20 zinc finger and BTB domain containing 20 0.0717751
TPT1 tumor protein, translationally-controlled 1 0.0709619
IGF2 insulin-like growth factor 2 0.0703755
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 0.0677555
ATXN1 ataxin 1 0.0668122
DST dystonin 0.0659885
TRIO trio Rho guanine nucleotide exchange factor 0.0658775
NDRG1 N-myc downstream regulated 1 0.065238
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.0626155
FLNB filamin B, beta 0.0619394
FMN1 formin 1 0.0617499
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.0604975
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0603067
EGFR epidermal growth factor receptor 0.0598028
DPYD dihydropyrimidine dehydrogenase 0.0584452
PALM2AKAP2 PALM2 and AKAP2 fusion 0.058142
HMGA2 high mobility group AT-hook 2 0.0569343
PBX3 pre-B-cell leukemia homeobox 3 0.0545849
ASAP1 ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 0.0541674
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1 0.0539428
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.0515885
ANGPTL4 angiopoietin-like 4 0.0502502
NT5E 5'-nucleotidase, ecto (CD73) 0.0497948
ESYT2 extended synaptotagmin-like protein 2 0.0487851
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 0.048193
JMJD1C jumonji domain containing 1C 0.0480697
PHLDB2 pleckstrin homology-like domain, family B, member 2 0.0480563
SMAD3 SMAD family member 3 0.0480324
FTH1 ferritin, heavy polypeptide 1 0.047279
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase 0.04598
SLC38A2 solute carrier family 38, member 2 0.0451045
ANXA2 annexin A2 0.0450662
GPC6 glypican 6 0.0441122
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.043721
BICD1 bicaudal D homolog 1 (Drosophila) 0.0435534
WWOX WW domain containing oxidoreductase 0.0432919
IL1RAP interleukin 1 receptor accessory protein 0.0429266
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.0428666
SBF2 SET binding factor 2 0.0410485
LPP LIM domain containing preferred translocation partner in lipoma 0.0405763
NALCN sodium leak channel, non selective 0.0395347
ZMYND8 zinc finger, MYND-type containing 8 0.0394091
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.0393424
PMEPA1 prostate transmembrane protein, androgen induced 1 0.0387758
RUNX1 runt-related transcription factor 1 0.0381987
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0374746
ERRFI1 ERBB receptor feedback inhibitor 1 0.0372796
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C 0.0369915
KLF12 Kruppel-like factor 12 0.036933
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.0368395
MAP3K20 mitogen-activated protein kinase kinase kinase 20 0.0365676
RANBP17 RAN binding protein 17 0.0365575
EXOC4 exocyst complex component 4 0.0364123
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.0359698
EXT1 exostosin glycosyltransferase 1 0.0359099
AKAP12 A kinase (PRKA) anchor protein 12 0.0357808
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats 0.0352454
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0348599
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.034034
STXBP1 syntaxin binding protein 1 0.0337404
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) 0.0335103
DERA deoxyribose-phosphate aldolase (putative) 0.0333507
NIBAN2 niban apoptosis regulator 2 0.0331311
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.0328497
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.0328294
GPC5 glypican 5 0.0319312
PCED1B PC-esterase domain containing 1B 0.0317195
ERC2 ELKS/RAB6-interacting/CAST family member 2 0.0313763
MACF1 microtubule-actin crosslinking factor 1 0.0311698
PAG1 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 0.030925
ITGAV integrin, alpha V 0.0304263
NAV3 neuron navigator 3 0.0300108
DLGAP4 discs, large (Drosophila) homolog-associated protein 4 0.0299759
MYO9B myosin IXB 0.0299303
DNER delta/notch-like EGF repeat containing 0.0294255
FNDC3A fibronectin type III domain containing 3A 0.0293295
TBC1D8 TBC1 domain family, member 8 (with GRAM domain) 0.029123
USP34 ubiquitin specific peptidase 34 0.0289891
MARK3 MAP/microtubule affinity-regulating kinase 3 0.028775
BZW1 basic leucine zipper and W2 domains 1 0.0286083
UGGT2 UDP-glucose glycoprotein glucosyltransferase 2 0.028436
IRAK2 interleukin-1 receptor-associated kinase 2 0.0282282
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0279522
SKIL SKI-like proto-oncogene 0.0277708
TSC22D1 TSC22 domain family, member 1 0.0276815
PATJ PATJ crumbs cell polarity complex component 0.0269521
PHF14 PHD finger protein 14 0.0268898
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like 0.0268792
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.0268695
ATXN7L1 ataxin 7-like 1 0.0267279
TMEM135 transmembrane protein 135 0.0264102
RABGEF1 RAB guanine nucleotide exchange factor (GEF) 1 0.02638
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 0.0263293

decreased expression

Symbol Name Standardized Value
PTMA prothymosin, alpha -0.102415
GOLGA4 golgin A4 -0.0932834
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.0909821
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa -0.0865705
RBM39 RNA binding motif protein 39 -0.0828635
CENPF centromere protein F, 350/400kDa -0.0810426
TPX2 TPX2, microtubule-associated -0.0802077
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) -0.0754343
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0720704
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.0656528
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 -0.0634696
NAP1L1 nucleosome assembly protein 1-like 1 -0.0594878
YBX3 Y box binding protein 3 -0.058385
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0579677
TOP2A topoisomerase (DNA) II alpha 170kDa -0.0533093
ANLN anillin, actin binding protein -0.0520446
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -0.0510983
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) -0.0501582
SREK1 splicing regulatory glutamine/lysine-rich protein 1 -0.049094
CHD1 chromodomain helicase DNA binding protein 1 -0.0468427
NUP58 nucleoporin 58 -0.046583
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) -0.0465094
RPS13 ribosomal protein S13 -0.0457772
MT2A metallothionein 2A -0.0455717
SMC4 structural maintenance of chromosomes 4 -0.0450837
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 -0.0446882
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 -0.0435007
FTL ferritin, light polypeptide -0.042935
IARS1 isoleucyl-tRNA synthetase 1 -0.0423437
RPS27A ribosomal protein S27a -0.0417933
GNAS GNAS complex locus -0.0406837
CKAP2 cytoskeleton associated protein 2 -0.0406635
CPNE1 copine I -0.0403335
PPP6R3 protein phosphatase 6, regulatory subunit 3 -0.0401251
HMGB2 high mobility group box 2 -0.0395199
RRBP1 ribosome binding protein 1 -0.0386823
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0386011
RPL26 ribosomal protein L26 -0.0381332
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 -0.0380289
CLTC clathrin, heavy chain (Hc) -0.0373743
KIF5B kinesin family member 5B -0.0373451
MATR3 matrin 3 -0.0372548
RPL12 ribosomal protein L12 -0.0367946
GOLGB1 golgin B1 -0.0365943
NKTR natural killer cell triggering receptor -0.0362467
TRA2A transformer 2 alpha homolog (Drosophila) -0.0359735
RSRC2 arginine/serine-rich coiled-coil 2 -0.0358508
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) -0.0351274
CBFA2T2 core-binding factor, runt domain, alpha subunit 2; translocated to, 2 -0.0349866
MRE11 MRE11 homolog, double strand break repair nuclease -0.0336009
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.03318
APOLD1 apolipoprotein L domain containing 1 -0.033155
RPL19 ribosomal protein L19 -0.0327098
ZNF292 zinc finger protein 292 -0.0325208
CKAP5 cytoskeleton associated protein 5 -0.0321813
KIF4A kinesin family member 4A -0.0320194
BRD2 bromodomain containing 2 -0.0317651
PUM2 pumilio RNA-binding family member 2 -0.0317225
DEK DEK proto-oncogene -0.0316713
AHCTF1 AT hook containing transcription factor 1 -0.0316642
ARL13B ADP-ribosylation factor-like 13B -0.0315653
COPB1 coatomer protein complex, subunit beta 1 -0.0314914
TAS2R14 taste receptor, type 2, member 14 -0.0307093
CANX calnexin -0.0306085
TFRC transferrin receptor -0.0304442
LDHB lactate dehydrogenase B -0.0302023
WDR43 WD repeat domain 43 -0.0301155
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.0300831
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.0299792
KANSL1 KAT8 regulatory NSL complex subunit 1 -0.0299716
PHF20 PHD finger protein 20 -0.0298028
RPL37A ribosomal protein L37a -0.0297845
IPO7 importin 7 -0.0295417
DIAPH3 diaphanous-related formin 3 -0.0294752
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.0294375
WAC WW domain containing adaptor with coiled-coil -0.0294157
TMEM167A transmembrane protein 167A -0.0292034
RAB1A RAB1A, member RAS oncogene family -0.0291916
GLS2 glutaminase 2 (liver, mitochondrial) -0.0291879
CALU calumenin -0.02914
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 -0.0291276
MYH9 myosin, heavy chain 9, non-muscle -0.029065
RB1CC1 RB1-inducible coiled-coil 1 -0.0287261
SKIC3 SKI3 subunit of superkiller complex -0.0287057
PDS5B PDS5 cohesin associated factor B -0.0286938
SETD5 SET domain containing 5 -0.0284505
USP22 ubiquitin specific peptidase 22 -0.028437
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa -0.0284006
SET SET nuclear proto-oncogene -0.0282984
BRD8 bromodomain containing 8 -0.0282908
EIF1 eukaryotic translation initiation factor 1 -0.0282844
VDAC1 voltage-dependent anion channel 1 -0.0282611
HMMR hyaluronan-mediated motility receptor (RHAMM) -0.0281768
NASP nuclear autoantigenic sperm protein (histone-binding) -0.0280209
WBP11 WW domain binding protein 11 -0.0278477
TAF7 TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa -0.0276183
TFG TRK-fused gene -0.0268386
LCORL ligand dependent nuclear receptor corepressor-like -0.0267423
RPL37 ribosomal protein L37 -0.026712
EEF2 eukaryotic translation elongation factor 2 -0.0267062