| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Thymol perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Thymol_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.213108 |
| FN1 | fibronectin 1 | 0.150203 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.142332 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.136104 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0985008 |
| AHR | aryl hydrocarbon receptor | 0.0805591 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0761248 |
| ITGA1 | integrin, alpha 1 | 0.0660464 |
| CD109 | CD109 molecule | 0.0647574 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0634203 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0631045 |
| TXNIP | thioredoxin interacting protein | 0.0629446 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0615471 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0578618 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0567929 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0566764 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0553403 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0534759 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0530996 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0530909 |
| TPR | translocated promoter region, nuclear basket protein | 0.0528272 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0524822 |
| ANXA5 | annexin A5 | 0.0522917 |
| FAM13A | family with sequence similarity 13, member A | 0.0520332 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0511661 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0509902 |
| SPAG9 | sperm associated antigen 9 | 0.0506086 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0485478 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0477858 |
| EREG | epiregulin | 0.0449022 |
| NRP1 | neuropilin 1 | 0.0442068 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0419236 |
| VEGFA | vascular endothelial growth factor A | 0.0405099 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0398128 |
| ASPH | aspartate beta-hydroxylase | 0.0393092 |
| TMEM165 | transmembrane protein 165 | 0.0386418 |
| ZNF292 | zinc finger protein 292 | 0.0383436 |
| NDRG1 | N-myc downstream regulated 1 | 0.0377455 |
| ARRDC3 | arrestin domain containing 3 | 0.0371987 |
| SMAD3 | SMAD family member 3 | 0.0371985 |
| WAC | WW domain containing adaptor with coiled-coil | 0.036585 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0362914 |
| ENO1 | enolase 1, (alpha) | 0.0362252 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0359477 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0352884 |
| TMEM156 | transmembrane protein 156 | 0.0352269 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0349956 |
| SFTPA2 | surfactant protein A2 | 0.0349617 |
| OSMR | oncostatin M receptor | 0.0334943 |
| CEP350 | centrosomal protein 350kDa | 0.0331414 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0331012 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.033076 |
| SFXN1 | sideroflexin 1 | 0.0326482 |
| FRYL | FRY-like | 0.0324792 |
| IL6ST | interleukin 6 signal transducer | 0.0319926 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0314352 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0310485 |
| S100A10 | S100 calcium binding protein A10 | 0.0309841 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0303636 |
| PLIN2 | perilipin 2 | 0.0300051 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0299233 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0298234 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0295857 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0295367 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0294214 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0293936 |
| TXNRD1 | thioredoxin reductase 1 | 0.0292531 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0291762 |
| OGA | O-GlcNAcase | 0.0291713 |
| FAT1 | FAT atypical cadherin 1 | 0.0289654 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0289296 |
| CAB39 | calcium binding protein 39 | 0.0288887 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0286209 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.028509 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.0284923 |
| MYO6 | myosin VI | 0.028251 |
| GOLGA4 | golgin A4 | 0.0282147 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0281598 |
| PELO | pelota homolog (Drosophila) | 0.0279474 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0278543 |
| FNBP1 | formin binding protein 1 | 0.0277205 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0277017 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0275177 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0273166 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.0273038 |
| MKI67 | marker of proliferation Ki-67 | 0.0272908 |
| CDCP1 | CUB domain containing protein 1 | 0.0271687 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0269909 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0269111 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0268246 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.026195 |
| KMT2A | lysine (K)-specific methyltransferase 2A | 0.0260869 |
| SNX9 | sorting nexin 9 | 0.0260798 |
| DSG2 | desmoglein 2 | 0.0260433 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0260075 |
| RNF145 | ring finger protein 145 | 0.0258427 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0258414 |
| FOXO3 | forkhead box O3 | 0.0256258 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0255267 |
| DENND5B | DENN/MADD domain containing 5B | 0.0253674 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.154191 |
| TMSB10 | thymosin beta 10 | -0.114545 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0726956 |
| PTMA | prothymosin, alpha | -0.0643528 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0580554 |
| MT2A | metallothionein 2A | -0.0576186 |
| S100A6 | S100 calcium binding protein A6 | -0.0512167 |
| GLIS3 | GLIS family zinc finger 3 | -0.0507003 |
| INTS6 | integrator complex subunit 6 | -0.0498198 |
| VCL | vinculin | -0.0437604 |
| AEBP2 | AE binding protein 2 | -0.0431308 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0387202 |
| RPL9 | ribosomal protein L9 | -0.0385937 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.037321 |
| EGR1 | early growth response 1 | -0.0371865 |
| ACTG1 | actin gamma 1 | -0.035734 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0350589 |
| SYT1 | synaptotagmin I | -0.0345816 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0345227 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0340437 |
| RPS21 | ribosomal protein S21 | -0.0332273 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0326773 |
| RPL26 | ribosomal protein L26 | -0.0313549 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0297121 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0294418 |
| POTEF | POTE ankyrin domain family, member F | -0.0294319 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0293723 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0290971 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0290136 |
| ACTN4 | actinin, alpha 4 | -0.0281047 |
| MCL1 | myeloid cell leukemia 1 | -0.0274537 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0273246 |
| S100A9 | S100 calcium binding protein A9 | -0.0269924 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0269545 |
| DPYD | dihydropyrimidine dehydrogenase | -0.026054 |
| RPS19 | ribosomal protein S19 | -0.0260123 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0253604 |
| TNS3 | tensin 3 | -0.0248155 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0246431 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0240896 |
| RPS23 | ribosomal protein S23 | -0.0238474 |
| SLC38A2 | solute carrier family 38, member 2 | -0.023513 |
| EFNA5 | ephrin-A5 | -0.0233071 |
| IFI44L | interferon-induced protein 44-like | -0.0225611 |
| RPL28 | ribosomal protein L28 | -0.0224547 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0217579 |
| CCDC138 | coiled-coil domain containing 138 | -0.021716 |
| FAM20C | family with sequence similarity 20, member C | -0.0213604 |
| RPL37A | ribosomal protein L37a | -0.0211098 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0210633 |
| RPL35A | ribosomal protein L35a | -0.0206697 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0206217 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0205822 |
| CADM1 | cell adhesion molecule 1 | -0.020559 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0204241 |
| ASTN2 | astrotactin 2 | -0.019879 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0198214 |
| RPL34 | ribosomal protein L34 | -0.0197404 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0196124 |
| ABR | active BCR-related | -0.0195317 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0194782 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0194192 |
| RPL19 | ribosomal protein L19 | -0.0194052 |
| CLIC4 | chloride intracellular channel 4 | -0.0193659 |
| TGFB1 | transforming growth factor, beta 1 | -0.0191355 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0191178 |
| STC2 | stanniocalcin 2 | -0.0188299 |
| CTSD | cathepsin D | -0.0187817 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0182567 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0182328 |
| RANBP17 | RAN binding protein 17 | -0.0181815 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0178869 |
| HLA-B | major histocompatibility complex, class I, B | -0.0177677 |
| MIDN | midnolin | -0.0177571 |
| RPL11 | ribosomal protein L11 | -0.0175443 |
| MT1X | metallothionein 1X | -0.0173905 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0173362 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0173013 |
| RPS3 | ribosomal protein S3 | -0.0172454 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0172164 |
| RPL31 | ribosomal protein L31 | -0.0171723 |
| KRT81 | keratin 81, type II | -0.0170337 |
| SEPTIN9 | septin 9 | -0.016967 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0169052 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.016813 |
| CFAP44 | cilia and flagella associated protein 44 | -0.0167078 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0166477 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0165491 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0165183 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.0161469 |
| CYBA | cytochrome b-245, alpha polypeptide | -0.0160183 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0158918 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0157794 |
| LMNA | lamin A/C | -0.0157434 |
| RPS8 | ribosomal protein S8 | -0.0156863 |
| NTN4 | netrin 4 | -0.0156778 |
| PRKCA | protein kinase C, alpha | -0.0155423 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0155194 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0154872 |
| HLA-A | major histocompatibility complex, class I, A | -0.0153884 |
