Thymoma Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A thymus cancer that derives_from epithelial cells located_in the thymus. The tumor cells in a thymoma look similar to the normal cells of the thymus, grow slowly, and rarely spread beyond the thymus. (Human Disease Ontology, DOID_3275)
External Link https://www.disgenet.org/browser/0/1/0/C1266091
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Genes

275 genes associated with the disease Thymoma in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ADRB2 adrenoceptor beta 2, surface
AHI1 Abelson helper integration site 1
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
AIRE autoimmune regulator
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANGPT1 angiopoietin 1
ANGPT2 angiopoietin 2
AQP4 aquaporin 4
ASXL1 additional sex combs like transcriptional regulator 1
ATM ATM serine/threonine kinase
AURKB aurora kinase B
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCOR BCL6 corepressor
BMI1 BMI1 proto-oncogene, polycomb ring finger
BMP2 bone morphogenetic protein 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRD4 bromodomain containing 4
CALCA calcitonin-related polypeptide alpha
CAMP cathelicidin antimicrobial peptide
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CASP3 caspase 3, apoptosis-related cysteine peptidase
CAT catalase
CAV3 caveolin 3
CCL25 chemokine (C-C motif) ligand 25
CCN1 cellular communication network factor 1
CCND1 cyclin D1
CCR7 chemokine (C-C motif) receptor 7
CD19 CD19 molecule
CD247 CD247 molecule
CD274 CD274 molecule
CD28 CD28 molecule
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD70 CD70 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD79A CD79a molecule, immunoglobulin-associated alpha
CDC42 cell division cycle 42
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK2 cyclin-dependent kinase 2
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CDS1 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
CFLAR CASP8 and FADD-like apoptosis regulator
CHD1L chromodomain helicase DNA binding protein 1-like
CHRNA1 cholinergic receptor, nicotinic, alpha 1 (muscle)
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CIITA class II, major histocompatibility complex, transactivator
CLEC14A C-type lectin domain family 14, member A
CLTA clathrin, light chain A
CNTNAP2 contactin associated protein-like 2
COL11A2 collagen, type XI, alpha 2
COX2
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CRMP1 collapsin response mediator protein 1
CSF1R colony stimulating factor 1 receptor
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSV cathepsin V
CTTN cortactin
CXCL13 chemokine (C-X-C motif) ligand 13
CXCR4 chemokine (C-X-C motif) receptor 4
CYLD cylindromatosis (turban tumor syndrome)
DAP3 death associated protein 3
DCC DCC netrin 1 receptor
DCTN6 dynactin 6
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DES desmin
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DPP4 dipeptidyl-peptidase 4
DPYD dihydropyrimidine dehydrogenase
DPYSL4 dihydropyrimidinase-like 4
DPYSL5 dihydropyrimidinase-like 5
EGFR epidermal growth factor receptor
EIF3K eukaryotic translation initiation factor 3, subunit K
EPO erythropoietin
ERBB2 erb-b2 receptor tyrosine kinase 2
ERRFI1 ERBB receptor feedback inhibitor 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
F11 coagulation factor XI
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FGF23 fibroblast growth factor 23
FHIT fragile histidine triad
FOLH1 folate hydrolase (prostate-specific membrane antigen) 1
FOXN1 forkhead box N1
FOXP3 forkhead box P3
FSD1 fibronectin type III and SPRY domain containing 1
FSD1L fibronectin type III and SPRY domain containing 1-like
FST follistatin
G6PD glucose-6-phosphate dehydrogenase
GADD45B growth arrest and DNA-damage-inducible, beta
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
GHSR growth hormone secretagogue receptor
GMFB glia maturation factor, beta
GPX1 glutathione peroxidase 1
GRAP2 GRB2-related adaptor protein 2
GSK3B glycogen synthase kinase 3 beta
GTF2I general transcription factor IIi
HACD1 3-hydroxyacyl-CoA dehydratase 1
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIF3A hypoxia inducible factor 3, alpha subunit
HLA-A major histocompatibility complex, class I, A
HLA-C major histocompatibility complex, class I, C
HLA-DPB1 major histocompatibility complex, class II, DP beta 1
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-DRB3 major histocompatibility complex, class II, DR beta 3
HLA-DRB5 major histocompatibility complex, class II, DR beta 5
HMGB1 high mobility group box 1
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HRAS Harvey rat sarcoma viral oncogene homolog
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7
ICAM1 intercellular adhesion molecule 1
IFI27 interferon, alpha-inducible protein 27
IFIH1 interferon induced with helicase C domain 1
IFNA2 interferon, alpha 2
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGFBP1 insulin-like growth factor binding protein 1
IL10 interleukin 10
IL12B interleukin 12B
IL15 interleukin 15
IL17A interleukin 17A
IL17F interleukin 17F
IL2 interleukin 2
IL22 interleukin 22
IL2RA interleukin 2 receptor, alpha
ISG20 interferon stimulated exonuclease gene 20kDa
JAK2 Janus kinase 2
KDR kinase insert domain receptor
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLRC4-KLRK1 KLRC4-KLRK1 readthrough
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KMT2C lysine (K)-specific methyltransferase 2C
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT19 keratin 19, type I
LCK LCK proto-oncogene, Src family tyrosine kinase
LGI1 leucine-rich, glioma inactivated 1
LMO2 LIM domain only 2 (rhombotin-like 1)
LNPEP leucyl/cystinyl aminopeptidase
LTA lymphotoxin alpha
LY75 lymphocyte antigen 75
LY75-CD302 LY75-CD302 readthrough
MAEA macrophage erythroblast attacher
MAP3K10 mitogen-activated protein kinase kinase kinase 10
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MB myoglobin
MCL1 myeloid cell leukemia 1
MECOM MDS1 and EVI1 complex locus
MEN1 multiple endocrine neoplasia I
MGMT O-6-methylguanine-DNA methyltransferase
MICA MHC class I polypeptide-related sequence A
MICB MHC class I polypeptide-related sequence B
MMP1 matrix metallopeptidase 1
MPST mercaptopyruvate sulfurtransferase
MSLN mesothelin
MSTO1 misato 1, mitochondrial distribution and morphology regulator
MTA1 metastasis associated 1
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
MYOG myogenin (myogenic factor 4)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NTN1 netrin 1
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
NUTM1 NUT midline carcinoma, family member 1
PARP1 poly (ADP-ribose) polymerase 1
PBRM1 polybromo 1
PCNA proliferating cell nuclear antigen
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDLIM7 PDZ and LIM domain 7 (enigma)
PDPN podoplanin
PIGF phosphatidylinositol glycan anchor biosynthesis, class F
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLIN2 perilipin 2
PMP22 peripheral myelin protein 22
POLDIP2 polymerase (DNA-directed), delta interacting protein 2
POU1F1 POU class 1 homeobox 1
PPARA peroxisome proliferator-activated receptor alpha
PRPF31 pre-mRNA processing factor 31
PRSS16 protease, serine, 16 (thymus)
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
PSMD9 proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
PTCRA pre T-cell antigen receptor alpha
PTEN phosphatase and tensin homolog
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTH parathyroid hormone
PTK2B protein tyrosine kinase 2 beta
PTN pleiotrophin
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRT protein tyrosine phosphatase, receptor type, T
RAD51B RAD51 paralog B
RARRES3 retinoic acid receptor responder (tazarotene induced) 3
RBM45 RNA binding motif protein 45
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPL36A ribosomal protein L36a
RPS6 ribosomal protein S6
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1
RUNX3 runt-related transcription factor 3
RYR1 ryanodine receptor 1 (skeletal)
RYR2 ryanodine receptor 2 (cardiac)
SALL3 spalt-like transcription factor 3
SCARA3 scavenger receptor class A, member 3
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SETD2 SET domain containing 2
SLC20A1 solute carrier family 20 (phosphate transporter), member 1
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SMAD4 SMAD family member 4
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SORBS1 sorbin and SH3 domain containing 1
SOX2 SRY (sex determining region Y)-box 2
SPINT2 serine peptidase inhibitor, Kunitz type, 2
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1
SST somatostatin
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STK24 serine/threonine kinase 24
SULT1E1 sulfotransferase family 1E, estrogen-preferring, member 1
TET2 tet methylcytosine dioxygenase 2
THY1 Thy-1 cell surface antigen
TICAM2 toll-like receptor adaptor molecule 2
TIMP1 TIMP metallopeptidase inhibitor 1
TLR3 toll-like receptor 3
TMED7 transmembrane emp24 protein transport domain containing 7
TMED7-TICAM2 TMED7-TICAM2 readthrough
TMEM109 transmembrane protein 109
TNF tumor necrosis factor
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNFRSF4 tumor necrosis factor receptor superfamily, member 4
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNFSF4 tumor necrosis factor (ligand) superfamily, member 4
TNS4 tensin 4
TP53 tumor protein p53
TP63 tumor protein p63
TREM1 triggering receptor expressed on myeloid cells 1
TSLP thymic stromal lymphopoietin
TTN titin
TTR transthyretin
TYMS thymidylate synthetase
UHRF1 ubiquitin-like with PHD and ring finger domains 1
ULBP1 UL16 binding protein 1
UNC5A unc-5 homolog A (C. elegans)
VEGFA vascular endothelial growth factor A
VIP vasoactive intestinal peptide
VNN2 vanin 2
WDR11 WD repeat domain 11
WNT4 wingless-type MMTV integration site family, member 4