Thymopentin_CHP-212 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Thymopentin perturbation in CHP-212 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Thymopentin_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
FAM13A family with sequence similarity 13, member A 0.0575617
HELZ helicase with zinc finger 0.0561595
OGA O-GlcNAcase 0.0326092
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.0303693
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 0.026868
WAC WW domain containing adaptor with coiled-coil 0.0265814
LPIN1 lipin 1 0.0261679
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0260128
XPO1 exportin 1 0.0259678
NAMPT nicotinamide phosphoribosyltransferase 0.0257635
UBA6 ubiquitin-like modifier activating enzyme 6 0.0248477
NPEPPS aminopeptidase puromycin sensitive 0.0240919
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.023661
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.0233308
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0227667
HMGB2 high mobility group box 2 0.0225791
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0225248
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0216289
TENT5A terminal nucleotidyltransferase 5A 0.0215359
KDM3A lysine (K)-specific demethylase 3A 0.0208179
DSCAM Down syndrome cell adhesion molecule 0.0204053
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 0.0200863
ERRFI1 ERBB receptor feedback inhibitor 1 0.0200809
SRP54 signal recognition particle 54kDa 0.0200096
PTK2 protein tyrosine kinase 2 0.0195631
SPAG9 sperm associated antigen 9 0.0193681
RAD21 RAD21 homolog (S. pombe) 0.018936
ZNF292 zinc finger protein 292 0.0188717
CDC27 cell division cycle 27 0.0188383
MEF2A myocyte enhancer factor 2A 0.018806
MARCHF6 membrane associated ring-CH-type finger 6 0.0182872
ESYT2 extended synaptotagmin-like protein 2 0.0178937
MXI1 MAX interactor 1, dimerization protein 0.0178863
DST dystonin 0.0178405
CKAP5 cytoskeleton associated protein 5 0.017827
PPP6R3 protein phosphatase 6, regulatory subunit 3 0.0176873
GOLGA4 golgin A4 0.0174952
GPCPD1 glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) 0.0172541
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0165985
UBE2O ubiquitin-conjugating enzyme E2O 0.0164759
SETD5 SET domain containing 5 0.0163669
KMT2E lysine (K)-specific methyltransferase 2E 0.0162707
AUH AU RNA binding protein/enoyl-CoA hydratase 0.0161983
AFDN afadin, adherens junction formation factor 0.0159777
MARK3 MAP/microtubule affinity-regulating kinase 3 0.0159068
CHD1 chromodomain helicase DNA binding protein 1 0.0157838
PHKB phosphorylase kinase, beta 0.0152671
PELI1 pellino E3 ubiquitin protein ligase 1 0.0151663
CASC3 cancer susceptibility candidate 3 0.0151007
HOOK2 hook microtubule-tethering protein 2 0.0150564
USP9Y ubiquitin specific peptidase 9, Y-linked 0.0147108
WDR49 WD repeat domain 49 0.0146552
TNRC6B trinucleotide repeat containing 6B 0.014652
SNX13 sorting nexin 13 0.0146142
SOS1 son of sevenless homolog 1 (Drosophila) 0.0145937
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 0.0145575
ITPRID2 ITPR interacting domain containing 2 0.0145261
GARS1 glycyl-tRNA synthetase 1 0.014427
FNDC3B fibronectin type III domain containing 3B 0.0143848
FNBP1 formin binding protein 1 0.0142793
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit 0.0141975
NCKAP1 NCK-associated protein 1 0.0141374
RNF145 ring finger protein 145 0.0141004
TAF1D TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa 0.0140398
ZNF451 zinc finger protein 451 0.0140284
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0139373
ARRDC3 arrestin domain containing 3 0.0139244
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 0.0137584
SUCO SUN domain containing ossification factor 0.0137202
TM9SF3 transmembrane 9 superfamily member 3 0.013581
CENPF centromere protein F, 350/400kDa 0.0135346
WDR45B WD repeat domain 45B 0.0135249
PREPL prolyl endopeptidase-like 0.0134563
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein 0.0133274
FXR1 fragile X mental retardation, autosomal homolog 1 0.0132963
TOP2B topoisomerase (DNA) II beta 180kDa 0.0130807
USPL1 ubiquitin specific peptidase like 1 0.0130627
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.0130431
NEK7 NIMA-related kinase 7 0.0129953
PPME1 protein phosphatase methylesterase 1 0.0128679
CEP95 centrosomal protein 95kDa 0.0128391
SSBP2 single-stranded DNA binding protein 2 0.0127342
PPP1R15B protein phosphatase 1, regulatory subunit 15B 0.0126938
SMG7 SMG7 nonsense mediated mRNA decay factor 0.0126876
UBQLN1 ubiquilin 1 0.0126063
USP12 ubiquitin specific peptidase 12 0.01253
YEATS2 YEATS domain containing 2 0.0124759
CCNT2 cyclin T2 0.0123711
AP2B1 adaptor-related protein complex 2, beta 1 subunit 0.0123171
PICALM phosphatidylinositol binding clathrin assembly protein 0.012245
UBA2 ubiquitin-like modifier activating enzyme 2 0.0122362
SSBP3 single stranded DNA binding protein 3 0.0122109
AKAP10 A kinase (PRKA) anchor protein 10 0.0121885
RFX7 regulatory factor X, 7 0.0121251
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.0121098
ANXA2 annexin A2 0.0120448
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 0.0120311
TLK2 tousled-like kinase 2 0.0119986
PAPOLA poly(A) polymerase alpha 0.0119319
YTHDC1 YTH domain containing 1 0.0117876

decreased expression

Symbol Name Standardized Value
IGF2 insulin-like growth factor 2 -0.325344
LSAMP limbic system-associated membrane protein -0.148929
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.145026
NRG1 neuregulin 1 -0.139659
NALF1 NALCN channel auxiliary factor 1 -0.129961
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 -0.119167
VCL vinculin -0.0906431
EXT1 exostosin glycosyltransferase 1 -0.0890372
RPS6 ribosomal protein S6 -0.0818573
RPL23 ribosomal protein L23 -0.075158
ACTG1 actin gamma 1 -0.0693052
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0687927
COL1A1 collagen, type I, alpha 1 -0.0670984
PTPRD protein tyrosine phosphatase, receptor type, D -0.0605677
VIM vimentin -0.0597804
FMN1 formin 1 -0.0591095
THSD4 thrombospondin, type I, domain containing 4 -0.0578007
BPTF bromodomain PHD finger transcription factor -0.0571384
RPL35A ribosomal protein L35a -0.0562375
BCAS3 breast carcinoma amplified sequence 3 -0.0554264
PTMA prothymosin, alpha -0.0522273
CRH corticotropin releasing hormone -0.0502498
PRKCA protein kinase C, alpha -0.0493258
TPT1 tumor protein, translationally-controlled 1 -0.0491702
RPLP1 ribosomal protein, large, P1 -0.0481785
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0481275
TMSB10 thymosin beta 10 -0.0479226
RPL19 ribosomal protein L19 -0.0477933
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0471752
LRFN5 leucine rich repeat and fibronectin type III domain containing 5 -0.0457191
PABPC1 poly(A) binding protein, cytoplasmic 1 -0.0451748
SLIT2 slit homolog 2 (Drosophila) -0.0444783
PLAT plasminogen activator, tissue -0.0441099
RPS3 ribosomal protein S3 -0.0433913
ZBTB20 zinc finger and BTB domain containing 20 -0.0430665
COL4A5 collagen, type IV, alpha 5 -0.0414743
EGR1 early growth response 1 -0.0403792
CADM2 cell adhesion molecule 2 -0.0402711
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -0.0389227
RPL34 ribosomal protein L34 -0.0388528
PTPRK protein tyrosine phosphatase, receptor type, K -0.0387245
RPS24 ribosomal protein S24 -0.0373336
ZNF804A zinc finger protein 804A -0.037304
RPL37A ribosomal protein L37a -0.0371767
FTL ferritin, light polypeptide -0.0370255
RPS19 ribosomal protein S19 -0.0356253
FRMD4A FERM domain containing 4A -0.0351083
KLHL13 kelch-like family member 13 -0.0348823
NREP neuronal regeneration related protein -0.0342372
SYT1 synaptotagmin I -0.0334555
LPP LIM domain containing preferred translocation partner in lipoma -0.0332916
MAPK10 mitogen-activated protein kinase 10 -0.0330999
GREM2 gremlin 2, DAN family BMP antagonist -0.0328972
TLE4 transducin-like enhancer of split 4 -0.0327476
DCAF7 DDB1 and CUL4 associated factor 7 -0.0318012
TPM4 tropomyosin 4 -0.0313705
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 -0.0305439
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 -0.0302373
DNM3 dynamin 3 -0.0301548
RPS12 ribosomal protein S12 -0.0301316
SLC38A2 solute carrier family 38, member 2 -0.0300977
PACS1 phosphofurin acidic cluster sorting protein 1 -0.0300866
RPL26 ribosomal protein L26 -0.030085
RNF213 ring finger protein 213 -0.0298332
LINGO2 leucine rich repeat and Ig domain containing 2 -0.0297783
SOX4 SRY (sex determining region Y)-box 4 -0.0297553
RPL36 ribosomal protein L36 -0.0296959
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) -0.0296861
RPS23 ribosomal protein S23 -0.0294981
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) -0.0294733
ATRX alpha thalassemia/mental retardation syndrome X-linked -0.0291423
RPL32 ribosomal protein L32 -0.0291027
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0287738
IER3 immediate early response 3 -0.0287083
RPL11 ribosomal protein L11 -0.0285712
UNC5C unc-5 homolog C (C. elegans) -0.0285651
BICD1 bicaudal D homolog 1 (Drosophila) -0.0285277
RPS8 ribosomal protein S8 -0.028514
ANTXR1 anthrax toxin receptor 1 -0.0284958
TPM1 tropomyosin 1 (alpha) -0.0284382
RPS14 ribosomal protein S14 -0.0280921
RACK1 receptor for activated C kinase 1 -0.0280507
DNAH14 dynein, axonemal, heavy chain 14 -0.0278014
RAD51B RAD51 paralog B -0.0277641
RPL7A ribosomal protein L7a -0.0277378
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0274442
RPL31 ribosomal protein L31 -0.0272783
NPAS2 neuronal PAS domain protein 2 -0.0271114
IGFBP3 insulin-like growth factor binding protein 3 -0.0269247
TPST1 tyrosylprotein sulfotransferase 1 -0.0266415
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) -0.0264318
B2M beta-2-microglobulin -0.0263804
CUX1 cut-like homeobox 1 -0.0263457
RPL12 ribosomal protein L12 -0.0263372
RAB7A RAB7A, member RAS oncogene family -0.0263308
RPS11 ribosomal protein S11 -0.0263144
GLCCI1 glucocorticoid induced 1 -0.026292
ARID1B AT rich interactive domain 1B (SWI1-like) -0.026286
CALD1 caldesmon 1 -0.0262359
PDZRN3 PDZ domain containing ring finger 3 -0.025924