| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Thymopentin perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Thymopentin_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.344777 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.254779 |
| APOB | apolipoprotein B | 0.252189 |
| FNDC3B | fibronectin type III domain containing 3B | 0.144117 |
| C3 | complement component 3 | 0.126357 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.107208 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0939343 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0803526 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0614893 |
| JMJD1C | jumonji domain containing 1C | 0.0595139 |
| MT2A | metallothionein 2A | 0.0591135 |
| TF | transferrin | 0.0590338 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0555129 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0545291 |
| GPC3 | glypican 3 | 0.054369 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.0530322 |
| AFDN | afadin, adherens junction formation factor | 0.0503166 |
| FN1 | fibronectin 1 | 0.0499547 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0496971 |
| ITGAV | integrin, alpha V | 0.048003 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0475623 |
| TRIM26 | tripartite motif containing 26 | 0.0475229 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0471786 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0454865 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.0454257 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0453854 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0437708 |
| CRLS1 | cardiolipin synthase 1 | 0.0434768 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.043455 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0427216 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.042634 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0422174 |
| SVIL | supervillin | 0.0416124 |
| RTN4 | reticulon 4 | 0.0408912 |
| PRRC2C | proline-rich coiled-coil 2C | 0.040473 |
| ENO1 | enolase 1, (alpha) | 0.0395766 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0393804 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.038599 |
| A2M | alpha-2-macroglobulin | 0.0382846 |
| SESTD1 | SEC14 and spectrin domains 1 | 0.0376385 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0374359 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0370863 |
| CFB | complement factor B | 0.0367914 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0364078 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | 0.0361692 |
| RPS6 | ribosomal protein S6 | 0.0354317 |
| SDC4 | syndecan 4 | 0.0353798 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0352856 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0352537 |
| MRTFA | myocardin related transcription factor A | 0.0351406 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | 0.0342802 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0334783 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0332927 |
| MATR3 | matrin 3 | 0.0331466 |
| APOA2 | apolipoprotein A-II | 0.0327111 |
| YAP1 | Yes-associated protein 1 | 0.0326123 |
| RPL11 | ribosomal protein L11 | 0.0325941 |
| IGFBP1 | insulin-like growth factor binding protein 1 | 0.0325351 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0321309 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0320339 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0316333 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0315013 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0314679 |
| GOLGA4 | golgin A4 | 0.0313014 |
| KIF5B | kinesin family member 5B | 0.0312538 |
| TOP1 | topoisomerase (DNA) I | 0.0311805 |
| DSPP | dentin sialophosphoprotein | 0.0309818 |
| MALT1 | MALT1 paracaspase | 0.0309704 |
| DSCAM | Down syndrome cell adhesion molecule | 0.030818 |
| RPS12 | ribosomal protein S12 | 0.0306348 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0306042 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0303089 |
| MED13L | mediator complex subunit 13-like | 0.0299995 |
| PHIP | pleckstrin homology domain interacting protein | 0.0298314 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0297691 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0294882 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0294821 |
| ZNF292 | zinc finger protein 292 | 0.0294653 |
| CPE | carboxypeptidase E | 0.0292664 |
| USP3 | ubiquitin specific peptidase 3 | 0.0292428 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0286604 |
| SNX9 | sorting nexin 9 | 0.0284979 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0282226 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0279915 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | 0.0277256 |
| QKI | QKI, KH domain containing, RNA binding | 0.0276649 |
| AHR | aryl hydrocarbon receptor | 0.0276132 |
| PTK2 | protein tyrosine kinase 2 | 0.0271846 |
| HLF | hepatic leukemia factor | 0.0269155 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0268808 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0268263 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0264678 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0264327 |
| NCKAP1 | NCK-associated protein 1 | 0.0264127 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0261657 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.025861 |
| RPL3 | ribosomal protein L3 | 0.0255828 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0255416 |
| USP47 | ubiquitin specific peptidase 47 | 0.0255017 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0253345 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.352064 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.187442 |
| EHBP1 | EH domain binding protein 1 | -0.0800624 |
| ASPH | aspartate beta-hydroxylase | -0.0762741 |
| GPC6 | glypican 6 | -0.0756769 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0755055 |
| INTS6 | integrator complex subunit 6 | -0.0638445 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0606551 |
| ATXN1 | ataxin 1 | -0.0551247 |
| RNF213 | ring finger protein 213 | -0.050829 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0450833 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0442361 |
| FRMD5 | FERM domain containing 5 | -0.0441577 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0428747 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0405105 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0385036 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0381958 |
| RIGI | RNA sensor RIG-I | -0.03754 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0369349 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0359107 |
| GK | glycerol kinase | -0.0350482 |
| ATP10A | ATPase, class V, type 10A | -0.0340609 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0330508 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0305864 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0304869 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0298582 |
| HDAC4 | histone deacetylase 4 | -0.0287626 |
| NABP1 | nucleic acid binding protein 1 | -0.0271874 |
| RAD51B | RAD51 paralog B | -0.0268315 |
| CP | ceruloplasmin (ferroxidase) | -0.0260068 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0259916 |
| NDRG1 | N-myc downstream regulated 1 | -0.0257311 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | -0.0256736 |
| MYO1E | myosin IE | -0.0253942 |
| SMAD3 | SMAD family member 3 | -0.0250721 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0250564 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0243651 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0241247 |
| FAM107B | family with sequence similarity 107, member B | -0.0240171 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0239249 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.023688 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0236075 |
| PALLD | palladin, cytoskeletal associated protein | -0.0235274 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0232998 |
| PRKCA | protein kinase C, alpha | -0.0231671 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.023166 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0230559 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0230361 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0226525 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0219116 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.021316 |
| HOMER1 | homer scaffolding protein 1 | -0.0211916 |
| ENKUR | enkurin, TRPC channel interacting protein | -0.0211593 |
| HPCAL1 | hippocalcin-like 1 | -0.0205571 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0204945 |
| PEG3 | paternally expressed 3 | -0.0203076 |
| SP100 | SP100 nuclear antigen | -0.0200329 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0197376 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.019466 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0189041 |
| FKTN | fukutin | -0.0186865 |
| AHNAK | AHNAK nucleoprotein | -0.0183286 |
| LRRC23 | leucine rich repeat containing 23 | -0.0180725 |
| ACTG1 | actin gamma 1 | -0.0179735 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0178792 |
| PLIN2 | perilipin 2 | -0.017628 |
| DST | dystonin | -0.0175695 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | -0.0174499 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0174271 |
| DNAH17 | dynein, axonemal, heavy chain 17 | -0.0173036 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0171701 |
| TNS3 | tensin 3 | -0.0170163 |
| SQSTM1 | sequestosome 1 | -0.0168683 |
| FLNB | filamin B, beta | -0.0165568 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0164499 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0164097 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0161549 |
| MX2 | MX dynamin-like GTPase 2 | -0.0161479 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.016051 |
| ENPP1 | ectonucleotide pyrophosphatase/phosphodiesterase 1 | -0.0159755 |
| MCL1 | myeloid cell leukemia 1 | -0.0157004 |
| STK17A | serine/threonine kinase 17a | -0.0154662 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0154244 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0154069 |
| PTCHD4 | patched domain containing 4 | -0.0153919 |
| STC2 | stanniocalcin 2 | -0.01526 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0152414 |
| CMIP | c-Maf inducing protein | -0.0152279 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | -0.0151971 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0150951 |
| RCC1 | regulator of chromosome condensation 1 | -0.0148758 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0148394 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0148071 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0147255 |
| PMM2 | phosphomannomutase 2 | -0.014677 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0146764 |
| STK39 | serine threonine kinase 39 | -0.0146755 |
| TRAPPC12 | trafficking protein particle complex 12 | -0.014651 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0146287 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0145838 |
