| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Thymopentin perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Thymopentin_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0649516 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0607885 |
| TXNRD1 | thioredoxin reductase 1 | 0.0577169 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.042763 |
| TPM3 | tropomyosin 3 | 0.0420607 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.041144 |
| FGB | fibrinogen beta chain | 0.0409083 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0362828 |
| CENPF | centromere protein F, 350/400kDa | 0.0337975 |
| RTN4 | reticulon 4 | 0.0318798 |
| YBX1 | Y box binding protein 1 | 0.0315967 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0310416 |
| WDR43 | WD repeat domain 43 | 0.0293989 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0284766 |
| USP3 | ubiquitin specific peptidase 3 | 0.0284525 |
| YBX3 | Y box binding protein 3 | 0.0275961 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0260948 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0257674 |
| ANLN | anillin, actin binding protein | 0.0235732 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0229635 |
| ZNF292 | zinc finger protein 292 | 0.0227754 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0227464 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0226141 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0225519 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0225199 |
| TPX2 | TPX2, microtubule-associated | 0.0218597 |
| ECT2 | epithelial cell transforming 2 | 0.0212546 |
| FAM168A | family with sequence similarity 168, member A | 0.0210871 |
| RPL4 | ribosomal protein L4 | 0.021022 |
| RFWD3 | ring finger and WD repeat domain 3 | 0.0206029 |
| RAD21 | RAD21 homolog (S. pombe) | 0.020318 |
| JAK1 | Janus kinase 1 | 0.0203008 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | 0.0201866 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0201405 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0200455 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0198441 |
| NUP58 | nucleoporin 58 | 0.0191467 |
| MKI67 | marker of proliferation Ki-67 | 0.0190956 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.019019 |
| WBP11 | WW domain binding protein 11 | 0.0189388 |
| RRM2 | ribonucleotide reductase M2 | 0.0183132 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0181861 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0176999 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0172138 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0170854 |
| TFG | TRK-fused gene | 0.0168873 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0168377 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0165171 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0164505 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0162794 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0161801 |
| RPL3 | ribosomal protein L3 | 0.016009 |
| KIF23 | kinesin family member 23 | 0.0159066 |
| CHN1 | chimerin 1 | 0.015829 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0155902 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0154271 |
| OLA1 | Obg-like ATPase 1 | 0.0152841 |
| RNF145 | ring finger protein 145 | 0.0150926 |
| PPME1 | protein phosphatase methylesterase 1 | 0.0150143 |
| XPO1 | exportin 1 | 0.0148217 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0147464 |
| SIN3A | SIN3 transcription regulator family member A | 0.0145545 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.0141998 |
| QKI | QKI, KH domain containing, RNA binding | 0.0135353 |
| RHEB | Ras homolog enriched in brain | 0.0135287 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0134929 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0134921 |
| MATR3 | matrin 3 | 0.0134058 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0132912 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.0132821 |
| CLU | clusterin | 0.0132601 |
| CRY1 | cryptochrome circadian clock 1 | 0.0131673 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | 0.0131587 |
| RPL7 | ribosomal protein L7 | 0.0131217 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0130275 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 0.0130005 |
| HBS1L | HBS1-like translational GTPase | 0.0129751 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0129479 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0129312 |
| TMEM123 | transmembrane protein 123 | 0.0128991 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0128706 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.012842 |
| RPS7 | ribosomal protein S7 | 0.0126611 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.012475 |
| PNN | pinin, desmosome associated protein | 0.0123515 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.012349 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0121184 |
| CMC2 | C-x(9)-C motif containing 2 | 0.0120012 |
| HSPA4 | heat shock 70kDa protein 4 | 0.0119214 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0119099 |
| SPAG5 | sperm associated antigen 5 | 0.0119043 |
| FBL | fibrillarin | 0.0117668 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.0117201 |
| LAPTM4A | lysosomal protein transmembrane 4 alpha | 0.0116717 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0116256 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0115394 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0115341 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.011523 |
| CYRIB | CYFIP related Rac1 interactor B | 0.0115086 |
| NUP153 | nucleoporin 153kDa | 0.0114601 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.275289 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.203512 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.153961 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.152235 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.132823 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.123271 |
| TMSB10 | thymosin beta 10 | -0.112847 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.10224 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0923612 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0905135 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0878508 |
| IGF2 | insulin-like growth factor 2 | -0.0831533 |
| CMIP | c-Maf inducing protein | -0.0812346 |
| ACTG1 | actin gamma 1 | -0.0723252 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0714381 |
| VIM | vimentin | -0.0689007 |
| PYGL | phosphorylase, glycogen, liver | -0.0664965 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0595554 |
| SVIL | supervillin | -0.0590196 |
| FMNL2 | formin-like 2 | -0.0586554 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0577159 |
| EGFR | epidermal growth factor receptor | -0.0562654 |
| IER3 | immediate early response 3 | -0.0559704 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0545058 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0540737 |
| OSMR | oncostatin M receptor | -0.0512827 |
| HLA-B | major histocompatibility complex, class I, B | -0.050094 |
| FLNB | filamin B, beta | -0.0489218 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0486422 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0472471 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0455793 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0454967 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0451396 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0448929 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0447082 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0446002 |
| USP34 | ubiquitin specific peptidase 34 | -0.0445556 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0435953 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0431059 |
| KYNU | kynureninase | -0.0420023 |
| S100A6 | S100 calcium binding protein A6 | -0.0418069 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0417158 |
| RBM39 | RNA binding motif protein 39 | -0.0401284 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0395632 |
| GLG1 | golgi glycoprotein 1 | -0.0394354 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0392188 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0386877 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0385387 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0382659 |
| COPA | coatomer protein complex, subunit alpha | -0.0382103 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0379301 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0372986 |
| NDRG1 | N-myc downstream regulated 1 | -0.0371447 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0363301 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0362748 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0357105 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0354675 |
| ACTN1 | actinin, alpha 1 | -0.0354477 |
| BICC1 | BicC family RNA binding protein 1 | -0.0354215 |
| LDHA | lactate dehydrogenase A | -0.0349416 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0349082 |
| CAVIN1 | caveolae associated protein 1 | -0.0347966 |
| POTEF | POTE ankyrin domain family, member F | -0.0347093 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0341911 |
| MYO1E | myosin IE | -0.0340922 |
| NF1 | neurofibromin 1 | -0.034029 |
| CUX1 | cut-like homeobox 1 | -0.0332557 |
| STC1 | stanniocalcin 1 | -0.0328739 |
| HLA-A | major histocompatibility complex, class I, A | -0.0326204 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0325569 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0325087 |
| MYOF | myoferlin | -0.0322784 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0315569 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.031205 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.031177 |
| EHBP1 | EH domain binding protein 1 | -0.0310802 |
| EGR1 | early growth response 1 | -0.0309684 |
| ANKRD11 | ankyrin repeat domain 11 | -0.030941 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.030655 |
| GLIS3 | GLIS family zinc finger 3 | -0.0304148 |
| VCL | vinculin | -0.0300964 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0295928 |
| NEBL | nebulette | -0.0295011 |
| MORF4L2 | mortality factor 4 like 2 | -0.0294216 |
| DST | dystonin | -0.0292268 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0288963 |
| PARD3 | par-3 family cell polarity regulator | -0.0287903 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0287 |
| NUMB | numb homolog (Drosophila) | -0.028473 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0283209 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.028166 |
| ATXN1 | ataxin 1 | -0.0270915 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0268698 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0268602 |
| USP36 | ubiquitin specific peptidase 36 | -0.0267533 |
| FTL | ferritin, light polypeptide | -0.0267354 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.026656 |
| CDK13 | cyclin-dependent kinase 13 | -0.0264146 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0263507 |
| GNAS | GNAS complex locus | -0.0261295 |
