| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Thymopentin perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Thymopentin_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.127127 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.105421 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0959929 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0894161 |
| MED13L | mediator complex subunit 13-like | 0.0834414 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0831909 |
| HELZ | helicase with zinc finger | 0.08146 |
| FOXJ3 | forkhead box J3 | 0.0778346 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.077494 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | 0.0757899 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0756041 |
| CD109 | CD109 molecule | 0.0700286 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0682105 |
| MATR3 | matrin 3 | 0.0679266 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0668052 |
| NF1 | neurofibromin 1 | 0.0665414 |
| RTN4 | reticulon 4 | 0.0662461 |
| RBM39 | RNA binding motif protein 39 | 0.0652341 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0625315 |
| PCBP2 | poly(rC) binding protein 2 | 0.0603376 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0591779 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0588451 |
| AK1 | adenylate kinase 1 | 0.0587368 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0583874 |
| TXNRD1 | thioredoxin reductase 1 | 0.0568974 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0558147 |
| PTK2 | protein tyrosine kinase 2 | 0.0547639 |
| DENND1A | DENN/MADD domain containing 1A | 0.0545237 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0525291 |
| AHNAK | AHNAK nucleoprotein | 0.0523446 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0504376 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0498732 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0494265 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0478705 |
| ZNF292 | zinc finger protein 292 | 0.0470549 |
| YTHDC1 | YTH domain containing 1 | 0.0457444 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0439962 |
| ANKRD17 | ankyrin repeat domain 17 | 0.0439444 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0404844 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0395875 |
| PRELID2 | PRELI domain containing 2 | 0.0382042 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0352594 |
| ERBIN | erbb2 interacting protein | 0.0350792 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0346198 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0327052 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0325439 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0323454 |
| RLF | rearranged L-myc fusion | 0.0310848 |
| CTBP2 | C-terminal binding protein 2 | 0.030344 |
| TCF12 | transcription factor 12 | 0.0297357 |
| GLG1 | golgi glycoprotein 1 | 0.0289782 |
| GOLGA4 | golgin A4 | 0.0285054 |
| SBF2 | SET binding factor 2 | 0.027734 |
| RPS23 | ribosomal protein S23 | 0.0275634 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0273027 |
| ANXA2 | annexin A2 | 0.0272486 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0253946 |
| S100A10 | S100 calcium binding protein A10 | 0.0251099 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0250108 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0249286 |
| DST | dystonin | 0.0247549 |
| FAM13A | family with sequence similarity 13, member A | 0.0245205 |
| CLTC | clathrin, heavy chain (Hc) | 0.0241967 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0240093 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0232361 |
| RNF213 | ring finger protein 213 | 0.023216 |
| VCL | vinculin | 0.0225643 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0224605 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0224125 |
| SETD5 | SET domain containing 5 | 0.0219416 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0212273 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0206172 |
| FMNL2 | formin-like 2 | 0.020464 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0193811 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0169402 |
| RPLP1 | ribosomal protein, large, P1 | 0.0164428 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0160158 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0151967 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0150406 |
| PDE10A | phosphodiesterase 10A | 0.0147911 |
| FTL | ferritin, light polypeptide | 0.0139179 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0135898 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0117874 |
| CHD9 | chromodomain helicase DNA binding protein 9 | 0.0117697 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0114485 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0113107 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.010513 |
| PARD3 | par-3 family cell polarity regulator | 0.0099717 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.00935762 |
| ATXN1 | ataxin 1 | 0.00859754 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.00850366 |
| MYO1E | myosin IE | 0.00841096 |
| EXT1 | exostosin glycosyltransferase 1 | 0.00759358 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.00669049 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | 0.00662945 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00529547 |
| RPL31 | ribosomal protein L31 | 0.00511583 |
| ACTN4 | actinin, alpha 4 | 0.00499141 |
| ENO1 | enolase 1, (alpha) | 0.00483571 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0046846 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.216501 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.145031 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.142068 |
| VIM | vimentin | -0.125502 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0838143 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0771571 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0769844 |
| TMSB10 | thymosin beta 10 | -0.0743414 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0741394 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0714899 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0594987 |
| ASPH | aspartate beta-hydroxylase | -0.0590283 |
| GRAMD1B | GRAM domain containing 1B | -0.0571278 |
| FRMD4A | FERM domain containing 4A | -0.0566105 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0555522 |
| COPA | coatomer protein complex, subunit alpha | -0.0526984 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0519975 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0517864 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0504974 |
| LMO7 | LIM domain 7 | -0.0496295 |
| HMGA2 | high mobility group AT-hook 2 | -0.0496231 |
| B2M | beta-2-microglobulin | -0.0482565 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.047877 |
| RPL37A | ribosomal protein L37a | -0.0478154 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0475581 |
| RPL35A | ribosomal protein L35a | -0.0475321 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.046678 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0466482 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0461502 |
| LSAMP | limbic system-associated membrane protein | -0.0455917 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0455108 |
| RPS3 | ribosomal protein S3 | -0.0414621 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0407219 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0406498 |
| INHBA | inhibin, beta A | -0.0398525 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0394669 |
| EZR | ezrin | -0.036902 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0368647 |
| CANX | calnexin | -0.0368128 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0361055 |
| RASA3 | RAS p21 protein activator 3 | -0.03582 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0357043 |
| IGF2 | insulin-like growth factor 2 | -0.035185 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0350849 |
| ACTG1 | actin gamma 1 | -0.0350798 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0338216 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0331262 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0328661 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0321697 |
| PKM | pyruvate kinase, muscle | -0.0312336 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | -0.0304689 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0293713 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0288716 |
| RPL12 | ribosomal protein L12 | -0.0275579 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0267669 |
| PRKCA | protein kinase C, alpha | -0.0264588 |
| MYOF | myoferlin | -0.0263748 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.025898 |
| JMJD1C | jumonji domain containing 1C | -0.0253904 |
| CDH13 | cadherin 13 | -0.0251106 |
| TPM4 | tropomyosin 4 | -0.0248809 |
| MMP1 | matrix metallopeptidase 1 | -0.0245211 |
| RPS19 | ribosomal protein S19 | -0.0239225 |
| SLK | STE20-like kinase | -0.023919 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0238248 |
| SRPK2 | SRSF protein kinase 2 | -0.0237381 |
| RPL23 | ribosomal protein L23 | -0.0235592 |
| BPTF | bromodomain PHD finger transcription factor | -0.0232611 |
| NDRG1 | N-myc downstream regulated 1 | -0.022661 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0225352 |
| SLC38A2 | solute carrier family 38, member 2 | -0.022324 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.021634 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0212755 |
| SMYD3 | SET and MYND domain containing 3 | -0.0208699 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0206077 |
| GPC6 | glypican 6 | -0.0205821 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0202435 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0201162 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0198202 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0196632 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | -0.0188622 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0177791 |
| RPS6 | ribosomal protein S6 | -0.0170945 |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) | -0.015969 |
| USP34 | ubiquitin specific peptidase 34 | -0.0153968 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0153768 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0149568 |
| OXR1 | oxidation resistance 1 | -0.0148927 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0148575 |
| RPL19 | ribosomal protein L19 | -0.0144678 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0143953 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0142214 |
| MED13 | mediator complex subunit 13 | -0.013844 |
| FLNB | filamin B, beta | -0.0138059 |
| NAV2 | neuron navigator 2 | -0.0133728 |
| LAMB3 | laminin, beta 3 | -0.0133169 |
| SEPTIN9 | septin 9 | -0.0132579 |
| TNS3 | tensin 3 | -0.0131016 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0127246 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0115559 |