| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Thymopentin perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Thymopentin_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PEG10 | paternally expressed 10 | 0.106948 |
| TSC22D2 | TSC22 domain family, member 2 | 0.104303 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0847559 |
| ZNF292 | zinc finger protein 292 | 0.0661425 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0628009 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0580233 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0521984 |
| USP3 | ubiquitin specific peptidase 3 | 0.0512224 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0450197 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.044412 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0437212 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0432889 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0412105 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.0385536 |
| NCKAP1 | NCK-associated protein 1 | 0.0384534 |
| MTF2 | metal response element binding transcription factor 2 | 0.0383873 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase | 0.0382601 |
| MATR3 | matrin 3 | 0.0379303 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0374166 |
| CDC73 | cell division cycle 73 | 0.0373597 |
| PDGFC | platelet derived growth factor C | 0.0369499 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0367417 |
| APP | amyloid beta (A4) precursor protein | 0.0364444 |
| STRN3 | striatin, calmodulin binding protein 3 | 0.0360749 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0360723 |
| RHEB | Ras homolog enriched in brain | 0.0359429 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0352641 |
| RTN4 | reticulon 4 | 0.034857 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0346851 |
| FIP1L1 | factor interacting with PAPOLA and CPSF1 | 0.0346276 |
| RLF | rearranged L-myc fusion | 0.0345873 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.03451 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0343358 |
| PGAP1 | post-GPI attachment to proteins 1 | 0.0335462 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0332287 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0330596 |
| PARD3 | par-3 family cell polarity regulator | 0.032937 |
| RYBP | RING1 and YY1 binding protein | 0.0327035 |
| SETD5 | SET domain containing 5 | 0.0321719 |
| TXNRD1 | thioredoxin reductase 1 | 0.0320632 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0317064 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0315916 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0314853 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0311092 |
| MEMO1 | mediator of cell motility 1 | 0.0310361 |
| RBM39 | RNA binding motif protein 39 | 0.030651 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0306398 |
| TMSB4X | thymosin beta 4, X-linked | 0.030612 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0304509 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.0303712 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0302242 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0301869 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0301791 |
| CFL2 | cofilin 2 (muscle) | 0.0293178 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0286562 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0286361 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0282856 |
| ZNF608 | zinc finger protein 608 | 0.0282828 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0280842 |
| NUP58 | nucleoporin 58 | 0.0274411 |
| ENAH | enabled homolog (Drosophila) | 0.0274206 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0272053 |
| MEF2A | myocyte enhancer factor 2A | 0.0271688 |
| SPAG9 | sperm associated antigen 9 | 0.0270844 |
| TM7SF3 | transmembrane 7 superfamily member 3 | 0.0267633 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0265495 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0263754 |
| WDR43 | WD repeat domain 43 | 0.0263735 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.026277 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | 0.0262554 |
| DST | dystonin | 0.0262419 |
| TPM3 | tropomyosin 3 | 0.026225 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0260058 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0259719 |
| H1-4 | H1.4 linker histone, cluster member | 0.0255657 |
| QKI | QKI, KH domain containing, RNA binding | 0.0255329 |
| TLK2 | tousled-like kinase 2 | 0.0255272 |
| OLA1 | Obg-like ATPase 1 | 0.0254291 |
| CLTC | clathrin, heavy chain (Hc) | 0.025375 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0253725 |
| NEK7 | NIMA-related kinase 7 | 0.0251472 |
| FEM1C | fem-1 homolog c (C. elegans) | 0.0249433 |
| MED13L | mediator complex subunit 13-like | 0.0249426 |
| KIF5B | kinesin family member 5B | 0.0248883 |
| CTNNBL1 | catenin, beta like 1 | 0.0248646 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0247674 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0247652 |
| PTK2 | protein tyrosine kinase 2 | 0.0247636 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0243533 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0243313 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0243099 |
| TBC1D12 | TBC1 domain family, member 12 | 0.0240958 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0240082 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | 0.0240048 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0239796 |
| FNBP1L | formin binding protein 1-like | 0.0239181 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0238946 |
| FAM168A | family with sequence similarity 168, member A | 0.0237242 |
| ANXA2 | annexin A2 | 0.0234601 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0233353 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.175577 |
| CADM2 | cell adhesion molecule 2 | -0.171365 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.126942 |
| COL11A1 | collagen, type XI, alpha 1 | -0.123431 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.12085 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.119217 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0910902 |
| PCDH9 | protocadherin 9 | -0.0902136 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0813263 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0799761 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0773082 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0768189 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0642704 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0640596 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0639049 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0626791 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0614756 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.059369 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0591408 |
| TMSB10 | thymosin beta 10 | -0.0591377 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.056828 |
| PHIP | pleckstrin homology domain interacting protein | -0.0556391 |
| GPC3 | glypican 3 | -0.055248 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0545763 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0539765 |
| LRRC4C | leucine rich repeat containing 4C | -0.052222 |
| NEBL | nebulette | -0.0512202 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0510165 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.045843 |
| NHSL1 | NHS-like 1 | -0.0447801 |
| SMYD3 | SET and MYND domain containing 3 | -0.0445547 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.043898 |
| RAD51B | RAD51 paralog B | -0.0429073 |
| RPS8 | ribosomal protein S8 | -0.0417338 |
| HMCN1 | hemicentin 1 | -0.0404599 |
| HS6ST2 | heparan sulfate 6-O-sulfotransferase 2 | -0.0399057 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0377057 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0375267 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0357547 |
| NTM | neurotrimin | -0.0355365 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.035298 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0349946 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0346192 |
| RPS27A | ribosomal protein S27a | -0.0342477 |
| COLGALT2 | collagen beta(1-O)galactosyltransferase 2 | -0.0341116 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0329086 |
| COL5A2 | collagen, type V, alpha 2 | -0.0326919 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0325488 |
| TENM3 | teneurin transmembrane protein 3 | -0.0324454 |
| CDH19 | cadherin 19, type 2 | -0.0318619 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0317785 |
| CUX1 | cut-like homeobox 1 | -0.0316569 |
| CDK13 | cyclin-dependent kinase 13 | -0.0308091 |
| ENO1 | enolase 1, (alpha) | -0.03073 |
| FOXP2 | forkhead box P2 | -0.0306652 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0305876 |
| BPTF | bromodomain PHD finger transcription factor | -0.0305556 |
| GNAS | GNAS complex locus | -0.0304991 |
| MEF2C | myocyte enhancer factor 2C | -0.0304797 |
| RPS6 | ribosomal protein S6 | -0.030473 |
| GSE1 | Gse1 coiled-coil protein | -0.0303337 |
| NXN | nucleoredoxin | -0.0300248 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0290922 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.029043 |
| RPL37A | ribosomal protein L37a | -0.0289144 |
| NRG1 | neuregulin 1 | -0.0287229 |
| MEIS2 | Meis homeobox 2 | -0.0285696 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0282974 |
| SCFD1 | sec1 family domain containing 1 | -0.0282573 |
| PRELID2 | PRELI domain containing 2 | -0.0280268 |
| SLC44A5 | solute carrier family 44, member 5 | -0.0276432 |
| SIK2 | salt-inducible kinase 2 | -0.0273942 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0271437 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0270382 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0267902 |
| COL3A1 | collagen, type III, alpha 1 | -0.0264628 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.025306 |
| ACTG1 | actin gamma 1 | -0.0251697 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0250372 |
| GPATCH8 | G patch domain containing 8 | -0.0249915 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0249338 |
| FST | follistatin | -0.0246374 |
| INTS6 | integrator complex subunit 6 | -0.0245932 |
| NPAS3 | neuronal PAS domain protein 3 | -0.024175 |
| GARRE1 | granule associated Rac and RHOG effector 1 | -0.0241319 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0241248 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0237899 |
| RPL9 | ribosomal protein L9 | -0.0236441 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0235095 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0233577 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.023287 |
| PHACTR4 | phosphatase and actin regulator 4 | -0.0232365 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0230697 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0228985 |
| RPS16 | ribosomal protein S16 | -0.0227616 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0227391 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0223815 |
| RPL37 | ribosomal protein L37 | -0.0223676 |
| RPL23 | ribosomal protein L23 | -0.0222925 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0222635 |