Thymopentin_SNU-1 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Thymopentin perturbation in SNU-1 cell line (Tahoe Therapeutics)
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Genes

200 genes differentially expressed following the Thymopentin_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0863285
TMSB4X thymosin beta 4, X-linked 0.0749462
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.0714857
MINDY2 MINDY lysine 48 deubiquitinase 2 0.0606137
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) 0.0567018
ADAM10 ADAM metallopeptidase domain 10 0.051791
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0505056
GOLGA4 golgin A4 0.0484864
ZNF292 zinc finger protein 292 0.0468796
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.045693
NAMPT nicotinamide phosphoribosyltransferase 0.0455216
TXNIP thioredoxin interacting protein 0.0447556
EML4 echinoderm microtubule associated protein like 4 0.040976
EZR ezrin 0.0408058
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0395553
KDM3A lysine (K)-specific demethylase 3A 0.0385802
PGK1 phosphoglycerate kinase 1 0.0360961
SQSTM1 sequestosome 1 0.0354856
CAMTA1 calmodulin binding transcription activator 1 0.0351751
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 0.0345324
QKI QKI, KH domain containing, RNA binding 0.0321867
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0313968
KMT2E lysine (K)-specific methyltransferase 2E 0.0305805
TXNRD1 thioredoxin reductase 1 0.029206
SMNDC1 survival motor neuron domain containing 1 0.0292021
ZEB1 zinc finger E-box binding homeobox 1 0.0282866
CDC73 cell division cycle 73 0.0276308
NCKAP1 NCK-associated protein 1 0.0276205
NBAS neuroblastoma amplified sequence 0.0273744
PUM2 pumilio RNA-binding family member 2 0.02731
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) 0.027232
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive 0.0271041
ECT2 epithelial cell transforming 2 0.027083
PICALM phosphatidylinositol binding clathrin assembly protein 0.0263618
USP3 ubiquitin specific peptidase 3 0.0262607
PYGB phosphorylase, glycogen; brain 0.0259694
AHNAK AHNAK nucleoprotein 0.0252547
RNF145 ring finger protein 145 0.024084
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0237477
AUH AU RNA binding protein/enoyl-CoA hydratase 0.0237082
DENND4A DENN/MADD domain containing 4A 0.0236271
ZCCHC7 zinc finger, CCHC domain containing 7 0.0235439
TMEM65 transmembrane protein 65 0.0228352
BRWD1 bromodomain and WD repeat domain containing 1 0.0228095
RBM25 RNA binding motif protein 25 0.0226589
ZMYM2 zinc finger, MYM-type 2 0.0224136
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.0217713
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 0.0214044
RTN4 reticulon 4 0.0212953
PTBP2 polypyrimidine tract binding protein 2 0.0212078
ADAM9 ADAM metallopeptidase domain 9 0.0210451
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha 0.0210375
SPATS2L spermatogenesis associated, serine-rich 2-like 0.021015
CLTC clathrin, heavy chain (Hc) 0.0207386
SCAF11 SR-related CTD-associated factor 11 0.0205159
RBPJ recombination signal binding protein for immunoglobulin kappa J region 0.0204298
SRPK2 SRSF protein kinase 2 0.0203403
YEATS2 YEATS domain containing 2 0.0202653
TNRC6B trinucleotide repeat containing 6B 0.0201833
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0201799
LPP LIM domain containing preferred translocation partner in lipoma 0.0201568
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.0201559
CNOT6L CCR4-NOT transcription complex, subunit 6-like 0.0199464
PAN3 PAN3 poly(A) specific ribonuclease subunit 0.0197508
HELZ helicase with zinc finger 0.0196484
FNDC3B fibronectin type III domain containing 3B 0.0193941
TMF1 TATA element modulatory factor 1 0.0193305
EPRS1 glutamyl-prolyl-tRNA synthetase 1 0.0193271
MAP3K2 mitogen-activated protein kinase kinase kinase 2 0.0190445
RAB1A RAB1A, member RAS oncogene family 0.0188469
COPB1 coatomer protein complex, subunit beta 1 0.0187781
TMEM39A transmembrane protein 39A 0.0185923
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase 0.0181556
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0181355
TFG TRK-fused gene 0.0181202
NUP58 nucleoporin 58 0.0181049
XPO1 exportin 1 0.0181031
MATR3 matrin 3 0.0179845
TTC3 tetratricopeptide repeat domain 3 0.0179592
WRN Werner syndrome, RecQ helicase-like 0.0179228
MON2 MON2 homolog (S. cerevisiae) 0.0178529
DSTN destrin (actin depolymerizing factor) 0.0176319
CERT1 ceramide transporter 1 0.0175862
DLG1 discs, large homolog 1 (Drosophila) 0.0175495
PRPF38B pre-mRNA processing factor 38B 0.017538
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase 0.0173628
PTGES3 prostaglandin E synthase 3 (cytosolic) 0.0171562
CD47 CD47 molecule 0.0171454
MEF2A myocyte enhancer factor 2A 0.0171361
TOP2B topoisomerase (DNA) II beta 180kDa 0.0170905
CDC27 cell division cycle 27 0.0170224
HNRNPK heterogeneous nuclear ribonucleoprotein K 0.0169677
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 0.0168371
RAB6A RAB6A, member RAS oncogene family 0.0167649
COPB2 coatomer protein complex, subunit beta 2 (beta prime) 0.0167065
FLNB filamin B, beta 0.0165267
KDM6A lysine (K)-specific demethylase 6A 0.016493
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.0164596
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.0162922
CHD1 chromodomain helicase DNA binding protein 1 0.0162756

decreased expression

Symbol Name Standardized Value
PDE4B phosphodiesterase 4B, cAMP-specific -0.0578437
FOXP1 forkhead box P1 -0.0459522
B3GALT1 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 -0.044796
RBMS3 RNA binding motif, single stranded interacting protein 3 -0.0405712
RPS3 ribosomal protein S3 -0.0360529
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0294135
GLI3 GLI family zinc finger 3 -0.0286225
RPL26 ribosomal protein L26 -0.0256814
RPL31 ribosomal protein L31 -0.0250371
RPL36 ribosomal protein L36 -0.0242877
RPL35A ribosomal protein L35a -0.0236247
POTEF POTE ankyrin domain family, member F -0.0233705
TMSB10 thymosin beta 10 -0.0231386
BMP10 bone morphogenetic protein 10 -0.0227192
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.0217992
RPS6 ribosomal protein S6 -0.0206001
RPLP1 ribosomal protein, large, P1 -0.0196672
EGFR epidermal growth factor receptor -0.0195583
RPL23 ribosomal protein L23 -0.0194555
CRPPA CDP-L-ribitol pyrophosphorylase A -0.0194501
RPLP2 ribosomal protein, large, P2 -0.019382
RPS8 ribosomal protein S8 -0.0192409
PDE7B phosphodiesterase 7B -0.0184287
MYO5C myosin VC -0.018009
RPL9 ribosomal protein L9 -0.0179939
RPL37A ribosomal protein L37a -0.01798
SDK1 sidekick cell adhesion molecule 1 -0.0179202
RPS12 ribosomal protein S12 -0.0175887
TPI1 triosephosphate isomerase 1 -0.0172143
PFN1 profilin 1 -0.0164293
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -0.0158771
RPL18 ribosomal protein L18 -0.0158626
NFE2L2 nuclear factor, erythroid 2-like 2 -0.0158102
RFC3 replication factor C (activator 1) 3, 38kDa -0.0156291
RPL32 ribosomal protein L32 -0.0154879
MT2A metallothionein 2A -0.0153758
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.01532
RPS19 ribosomal protein S19 -0.0152919
FER1L6 fer-1-like family member 6 -0.0150878
CUX1 cut-like homeobox 1 -0.0148733
RPS29 ribosomal protein S29 -0.0146548
MACROD2 MACRO domain containing 2 -0.0145257
AEBP2 AE binding protein 2 -0.0144045
ENO2 enolase 2 (gamma, neuronal) -0.0143956
PRUNE2 prune homolog 2 (Drosophila) -0.0142059
SPRY4 sprouty homolog 4 (Drosophila) -0.0137725
RPL19 ribosomal protein L19 -0.01358
ANKRD17 ankyrin repeat domain 17 -0.0134068
FTL ferritin, light polypeptide -0.0133657
RPL28 ribosomal protein L28 -0.0130136
ENTPD6 ectonucleoside triphosphate diphosphohydrolase 6 (putative) -0.0130134
NBEA neurobeachin -0.0128446
SRSF6 serine/arginine-rich splicing factor 6 -0.0128307
RPS11 ribosomal protein S11 -0.0124329
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 -0.0123575
PARD3B par-3 family cell polarity regulator beta -0.0123271
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L -0.0123194
NEBL nebulette -0.0121787
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0121178
RPS23 ribosomal protein S23 -0.0120063
NPAS2 neuronal PAS domain protein 2 -0.0118073
PKM pyruvate kinase, muscle -0.0115532
SERF2 small EDRK-rich factor 2 -0.0114587
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 -0.011309
ANXA1 annexin A1 -0.0111813
EMP3 epithelial membrane protein 3 -0.0111619
CALM1 calmodulin 1 (phosphorylase kinase, delta) -0.011061
PDE4D phosphodiesterase 4D, cAMP-specific -0.0110412
CAMKMT calmodulin-lysine N-methyltransferase -0.0108641
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -0.0108144
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 -0.0108037
RPS27 ribosomal protein S27 -0.0107979
CPED1 cadherin-like and PC-esterase domain containing 1 -0.0107735
DIAPH3 diaphanous-related formin 3 -0.0106479
BPTF bromodomain PHD finger transcription factor -0.0105854
RPS25 ribosomal protein S25 -0.0105503
CFAP44 cilia and flagella associated protein 44 -0.0104488
PKP4 plakophilin 4 -0.0103882
SMC4 structural maintenance of chromosomes 4 -0.0102664
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 -0.0102582
INTS6 integrator complex subunit 6 -0.010224
RPS5 ribosomal protein S5 -0.0100897
RPS13 ribosomal protein S13 -0.0100878
RPL7A ribosomal protein L7a -0.00980886
LOC102724023 ES1 protein homolog, mitochondrial -0.00975946
RPL27 ribosomal protein L27 -0.00965966
RPS20 ribosomal protein S20 -0.00965045
PTPRG protein tyrosine phosphatase, receptor type, G -0.00965021
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.00924973
ARHGAP25 Rho GTPase activating protein 25 -0.00924811
GSE1 Gse1 coiled-coil protein -0.00922753
ZNF438 zinc finger protein 438 -0.00905725
RPL37 ribosomal protein L37 -0.0089574
SATB2 SATB homeobox 2 -0.00891897
STAU2 staufen double-stranded RNA binding protein 2 -0.00887817
TPT1 tumor protein, translationally-controlled 1 -0.00886587
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1 -0.0088561
PRSS23 protease, serine, 23 -0.00884016
ONECUT2 one cut homeobox 2 -0.00881849
TIAM2 T-cell lymphoma invasion and metastasis 2 -0.00879179