Thyroid Associated Opthalmopathies Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0339143
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Genes

198 genes associated with the disease Thyroid Associated Opthalmopathies in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
ACHE acetylcholinesterase (Yt blood group)
ACOT11 acyl-CoA thioesterase 11
ACTB actin, beta
ADIPOQ adiponectin, C1Q and collagen domain containing
AHR aryl hydrocarbon receptor
AIRE autoimmune regulator
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
APRT adenine phosphoribosyltransferase
ARRB1 arrestin, beta 1
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BCAR1 breast cancer anti-estrogen resistance 1
BCL2 B-cell CLL/lymphoma 2
BMP7 bone morphogenetic protein 7
BOLL boule-like RNA-binding protein
CASQ1 calsequestrin 1 (fast-twitch, skeletal muscle)
CASQ2 calsequestrin 2 (cardiac muscle)
CCL2 chemokine (C-C motif) ligand 2
CCL5 chemokine (C-C motif) ligand 5
CCN1 cellular communication network factor 1
CCN2 cellular communication network factor 2
CCR6 chemokine (C-C motif) receptor 6
CD19 CD19 molecule
CD28 CD28 molecule
CD34 CD34 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD40LG CD40 ligand
CD44 CD44 molecule (Indian blood group)
CD68 CD68 molecule
CD80 CD80 molecule
CD86 CD86 molecule
CDK5 cyclin-dependent kinase 5
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CHUK conserved helix-loop-helix ubiquitous kinase
CLN3 ceroid-lipofuscinosis, neuronal 3
COX2
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous)
CRABP1 cellular retinoic acid binding protein 1
CRP C-reactive protein, pentraxin-related
CSE1L CSE1 chromosome segregation 1-like (yeast)
CTLA4 cytotoxic T-lymphocyte-associated protein 4
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CXCL10 chemokine (C-X-C motif) ligand 10
CXCL11 chemokine (C-X-C motif) ligand 11
CXCL8 chemokine (C-X-C motif) ligand 8
CXCL9 chemokine (C-X-C motif) ligand 9
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DEFA3 defensin, alpha 3, neutrophil-specific
DIO2 deiodinase, iodothyronine, type II
EBI3 Epstein-Barr virus induced 3
EFS embryonal Fyn-associated substrate
FAM155B family with sequence similarity 155, member B
FGF1 fibroblast growth factor 1 (acidic)
FGF2 fibroblast growth factor 2 (basic)
FGFR1 fibroblast growth factor receptor 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXP3 forkhead box P3
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GDF1 growth differentiation factor 1
GIF gastric intrinsic factor (vitamin B synthesis)
GNAS GNAS complex locus
GNL1 guanine nucleotide binding protein-like 1
GSTP1 glutathione S-transferase pi 1
HAS2 hyaluronan synthase 2
HAVCR2 hepatitis A virus cellular receptor 2
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HLA-C major histocompatibility complex, class I, C
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HMGA2 high mobility group AT-hook 2
HSPA1A heat shock 70kDa protein 1A
HSPA1B heat shock 70kDa protein 1B
HSPA4 heat shock 70kDa protein 4
ICAM1 intercellular adhesion molecule 1
IFIH1 interferon induced with helicase C domain 1
IFNG interferon, gamma
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGFBP5 insulin-like growth factor binding protein 5
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL10 interleukin 10
IL12B interleukin 12B
IL13 interleukin 13
IL15 interleukin 15
IL16 interleukin 16
IL17A interleukin 17A
IL18 interleukin 18
IL18R1 interleukin 18 receptor 1
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2 interleukin 2
IL21 interleukin 21
IL22 interleukin 22
IL23A interleukin 23, alpha subunit p19
IL23R interleukin 23 receptor
IL2RA interleukin 2 receptor, alpha
IL3 interleukin 3
IL4 interleukin 4
IL5 interleukin 5
IL6 interleukin 6
IL6R interleukin 6 receptor
IL7 interleukin 7
IL7R interleukin 7 receptor
ISG20 interferon stimulated exonuclease gene 20kDa
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide)
KNTC1 kinetochore associated 1
KRT20 keratin 20, type I
LACRT lacritin
LDLR low density lipoprotein receptor
LEP leptin
LTA lymphotoxin alpha
LYZ lysozyme
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAVS mitochondrial antiviral signaling protein
MBP myelin basic protein
MBTPS1 membrane-bound transcription factor peptidase, site 1
MFAP1 microfibrillar-associated protein 1
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MS4A1 membrane-spanning 4-domains, subfamily A, member 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYD88 myeloid differentiation primary response 88
NAMPT nicotinamide phosphoribosyltransferase
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFE2L2 nuclear factor, erythroid 2-like 2
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NOTCH2 notch 2
NQO1 NAD(P)H dehydrogenase, quinone 1
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OMG oligodendrocyte myelin glycoprotein
PARP1 poly (ADP-ribose) polymerase 1
PDCD1 programmed cell death 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIP prolactin-induced protein
PPARA peroxisome proliferator-activated receptor alpha
PPARG peroxisome proliferator-activated receptor gamma
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAA2 protein kinase, AMP-activated, alpha 2 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRR3 proline rich 3
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTX3 pentraxin 3, long
RBM45 RNA binding motif protein 45
RBP1 retinol binding protein 1, cellular
RNH1 ribonuclease/angiogenin inhibitor 1
S100A4 S100 calcium binding protein A4
S100A8 S100 calcium binding protein A8
S1PR1 sphingosine-1-phosphate receptor 1
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SELE selectin E
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
SFRP1 secreted frizzled-related protein 1
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SNED1 sushi, nidogen and EGF-like domains 1
SOAT1 sterol O-acyltransferase 1
SOCS3 suppressor of cytokine signaling 3
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding)
SPHK1 sphingosine kinase 1
SST somatostatin
SSTR1 somatostatin receptor 1
SSTR2 somatostatin receptor 2
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
STAT1 signal transducer and activator of transcription 1, 91kDa
TG thyroglobulin
TGFB1 transforming growth factor, beta 1
THY1 Thy-1 cell surface antigen
TIMP1 TIMP metallopeptidase inhibitor 1
TIMP2 TIMP metallopeptidase inhibitor 2
TLR4 toll-like receptor 4
TLR7 toll-like receptor 7
TLR9 toll-like receptor 9
TNF tumor necrosis factor
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TPO thyroid peroxidase
TPP1 tripeptidyl peptidase I
TSHR thyroid stimulating hormone receptor
TSLP thymic stromal lymphopoietin
TYRP1 tyrosinase-related protein 1
UACA uveal autoantigen with coiled-coil domains and ankyrin repeats
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
ZFP36 ZFP36 ring finger protein