Thyrotoxicosis Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
Description A thyroid gland disease that is characterized by excess thyroid hormone. (Human Disease Ontology, DOID_7997)
External Link https://www.disgenet.org/browser/0/1/0/C0040156
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Genes

36 genes associated with the disease Thyrotoxicosis in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ADRA2A adrenoceptor alpha 2A
ADRB1 adrenoceptor beta 1
ALB albumin
CD274 CD274 molecule
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GDF1 growth differentiation factor 1
HOXD13 homeobox D13
IL10 interleukin 10
IL6 interleukin 6
IYD iodotyrosine deiodinase
MT-CYB cytochrome b
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
PDCD1 programmed cell death 1
PER2 period circadian clock 2
PPP1R13L protein phosphatase 1, regulatory subunit 13 like
PTH parathyroid hormone
RET ret proto-oncogene
RNH1 ribonuclease/angiogenin inhibitor 1
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
TG thyroglobulin
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TNS3 tensin 3
TPO thyroid peroxidase
TRH thyrotropin-releasing hormone
TSHR thyroid stimulating hormone receptor
TTR transthyretin
TXNRD2 thioredoxin reductase 2
UCP2 uncoupling protein 2 (mitochondrial, proton carrier)