| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tirabrutinib perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tirabrutinib_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.17875 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.138848 |
| NCKAP5 | NCK-associated protein 5 | 0.107746 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0919349 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0820726 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0775611 |
| MEIS2 | Meis homeobox 2 | 0.0772898 |
| MACC1 | metastasis associated in colon cancer 1 | 0.074984 |
| FAT1 | FAT atypical cadherin 1 | 0.0702677 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0701548 |
| PRKCA | protein kinase C, alpha | 0.0663711 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0651895 |
| ABHD2 | abhydrolase domain containing 2 | 0.0648676 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0639976 |
| TXNIP | thioredoxin interacting protein | 0.0621034 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0597263 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0586583 |
| ITGA6 | integrin, alpha 6 | 0.0582202 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.056258 |
| IFNGR1 | interferon gamma receptor 1 | 0.0552839 |
| MUC13 | mucin 13, cell surface associated | 0.0552792 |
| VMP1 | vacuole membrane protein 1 | 0.0549957 |
| B2M | beta-2-microglobulin | 0.0543633 |
| ATP10B | ATPase, class V, type 10B | 0.0533557 |
| ASPH | aspartate beta-hydroxylase | 0.0498554 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | 0.0489588 |
| PTGR1 | prostaglandin reductase 1 | 0.0456813 |
| PRELID2 | PRELI domain containing 2 | 0.045086 |
| EZR | ezrin | 0.0447782 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0445453 |
| ETV6 | ets variant 6 | 0.0440964 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0438582 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0429014 |
| FOXP1 | forkhead box P1 | 0.0422783 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0420516 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0417538 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0416941 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | 0.0402489 |
| RAD51B | RAD51 paralog B | 0.0401376 |
| TC2N | tandem C2 domains, nuclear | 0.0398723 |
| DSPP | dentin sialophosphoprotein | 0.0396977 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0394499 |
| TXNRD1 | thioredoxin reductase 1 | 0.0393882 |
| DST | dystonin | 0.0386915 |
| TRERF1 | transcriptional regulating factor 1 | 0.0382774 |
| FMN1 | formin 1 | 0.0381783 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0381262 |
| GRK3 | G protein-coupled receptor kinase 3 | 0.0381215 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0377994 |
| ALPK1 | alpha-kinase 1 | 0.0377649 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.037586 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.037377 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0373607 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0370315 |
| STK24 | serine/threonine kinase 24 | 0.0368176 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.0366214 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.0365557 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0364734 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.036326 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | 0.0363183 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0359019 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0356048 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.035563 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0349514 |
| CCNL1 | cyclin L1 | 0.0348434 |
| MX1 | MX dynamin-like GTPase 1 | 0.0341574 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.033515 |
| ZNRF3 | zinc and ring finger 3 | 0.0334885 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0332873 |
| ATXN1 | ataxin 1 | 0.0328648 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0327281 |
| SPATA6L | spermatogenesis associated 6-like | 0.0325887 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.032415 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0322094 |
| MSI2 | musashi RNA-binding protein 2 | 0.03202 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | 0.031291 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0311235 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0308946 |
| UTRN | utrophin | 0.0308005 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | 0.0302594 |
| DGKH | diacylglycerol kinase, eta | 0.0302323 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.029947 |
| SYT1 | synaptotagmin I | 0.0298497 |
| CD46 | CD46 molecule, complement regulatory protein | 0.029687 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0295 |
| SAMD12 | sterile alpha motif domain containing 12 | 0.0294294 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0293681 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.0292863 |
| ANXA4 | annexin A4 | 0.0285983 |
| SH3PXD2A | SH3 and PX domains 2A | 0.028247 |
| SCARB1 | scavenger receptor class B, member 1 | 0.0280575 |
| CMIP | c-Maf inducing protein | 0.0280537 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0279399 |
| TJP2 | tight junction protein 2 | 0.0277183 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.027565 |
| STK39 | serine threonine kinase 39 | 0.0275488 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0274951 |
| CDHR2 | cadherin-related family member 2 | 0.0272871 |
| DENND4C | DENN/MADD domain containing 4C | 0.0272704 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0272463 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.152077 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.125522 |
| INTS6 | integrator complex subunit 6 | -0.112991 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0977578 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0820441 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.063448 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0596996 |
| CANX | calnexin | -0.058477 |
| HDLBP | high density lipoprotein binding protein | -0.0572272 |
| RRBP1 | ribosome binding protein 1 | -0.0568411 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.055683 |
| SQSTM1 | sequestosome 1 | -0.0545627 |
| AHI1 | Abelson helper integration site 1 | -0.0532785 |
| SEC24D | SEC24 family member D | -0.048177 |
| HM13 | histocompatibility (minor) 13 | -0.0473025 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0468219 |
| SMAD3 | SMAD family member 3 | -0.0467188 |
| MAP7 | microtubule-associated protein 7 | -0.0457751 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0453631 |
| COG6 | component of oligomeric golgi complex 6 | -0.0425448 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0419753 |
| MORF4L2 | mortality factor 4 like 2 | -0.0394604 |
| PLSCR2 | phospholipid scramblase 2 | -0.0392353 |
| ANXA2 | annexin A2 | -0.0389022 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0375235 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0371566 |
| RPL35A | ribosomal protein L35a | -0.036908 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0367885 |
| RPL34 | ribosomal protein L34 | -0.0354214 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0351397 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0346725 |
| RPS6 | ribosomal protein S6 | -0.034664 |
| HLA-B | major histocompatibility complex, class I, B | -0.0337077 |
| SHB | Src homology 2 domain containing adaptor protein B | -0.0327405 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0317844 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0312648 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0311709 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0311252 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0305677 |
| PERP | PERP, TP53 apoptosis effector | -0.0300918 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0299819 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0298362 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.029249 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0290596 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0290452 |
| ARF1 | ADP-ribosylation factor 1 | -0.028863 |
| VCL | vinculin | -0.028698 |
| RPLP0 | ribosomal protein, large, P0 | -0.0285812 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.028525 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0282595 |
| RIGI | RNA sensor RIG-I | -0.0279947 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0278528 |
| PMM2 | phosphomannomutase 2 | -0.027819 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0274169 |
| SEC24A | SEC24 family member A | -0.0272873 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0271741 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0270695 |
| GOLGA3 | golgin A3 | -0.026898 |
| COG3 | component of oligomeric golgi complex 3 | -0.0267762 |
| RNF213 | ring finger protein 213 | -0.026682 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0265824 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0262793 |
| TNS4 | tensin 4 | -0.0260958 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0260949 |
| GOLGA4 | golgin A4 | -0.0259235 |
| SPAG9 | sperm associated antigen 9 | -0.0258704 |
| RPL19 | ribosomal protein L19 | -0.025753 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.025511 |
| RPS24 | ribosomal protein S24 | -0.0253729 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0249145 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0249136 |
| TJP1 | tight junction protein 1 | -0.0249046 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0248733 |
| GNAS | GNAS complex locus | -0.0247454 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0245447 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0241705 |
| PDIA5 | protein disulfide isomerase family A, member 5 | -0.0239621 |
| AGR2 | anterior gradient 2 | -0.0238824 |
| TMSB10 | thymosin beta 10 | -0.0237341 |
| FTL | ferritin, light polypeptide | -0.0237001 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0236491 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0235229 |
| GOLGB1 | golgin B1 | -0.0235035 |
| GOLGA2 | golgin A2 | -0.023388 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0232076 |
| RPL23 | ribosomal protein L23 | -0.0230998 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0230328 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | -0.0230274 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0229614 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0225064 |
| SSR1 | signal sequence receptor, alpha | -0.0224743 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0224123 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0224013 |
| GOSR2 | golgi SNAP receptor complex member 2 | -0.022375 |
| SETX | senataxin | -0.0222197 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0221732 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0220188 |
| SSR2 | signal sequence receptor, beta (translocon-associated protein beta) | -0.0219877 |
| ACTG1 | actin gamma 1 | -0.0217019 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0216144 |
