| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tirabrutinib perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tirabrutinib_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ANKRD28 | ankyrin repeat domain 28 | 0.0806301 |
| TXNRD1 | thioredoxin reductase 1 | 0.0798036 |
| ZNF292 | zinc finger protein 292 | 0.0753008 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0645935 |
| DST | dystonin | 0.0592152 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0583169 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.055901 |
| TPX2 | TPX2, microtubule-associated | 0.0552575 |
| FAM3C | family with sequence similarity 3, member C | 0.0550183 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0547669 |
| DIAPH3 | diaphanous-related formin 3 | 0.0514063 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0501306 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0496456 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0494517 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0487478 |
| ECT2 | epithelial cell transforming 2 | 0.0478391 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0471405 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0458899 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.045753 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0454052 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0445095 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0444036 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.044066 |
| ATP13A3 | ATPase type 13A3 | 0.0439082 |
| ANLN | anillin, actin binding protein | 0.0426011 |
| YAP1 | Yes-associated protein 1 | 0.0424036 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0423626 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0422794 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0422324 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.041267 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0392685 |
| PKM | pyruvate kinase, muscle | 0.0391614 |
| CENPF | centromere protein F, 350/400kDa | 0.0389148 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0388948 |
| CD44 | CD44 molecule (Indian blood group) | 0.0388097 |
| MSN | moesin | 0.038361 |
| RTN4 | reticulon 4 | 0.0381516 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0377476 |
| SLMAP | sarcolemma associated protein | 0.0375158 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.037444 |
| ANKRD36C | ankyrin repeat domain 36C | 0.0373514 |
| STK24 | serine/threonine kinase 24 | 0.0366672 |
| SIN3A | SIN3 transcription regulator family member A | 0.0366429 |
| RNF145 | ring finger protein 145 | 0.0366185 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0364179 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0362188 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0362097 |
| NBAS | neuroblastoma amplified sequence | 0.0355307 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0354449 |
| NAV2 | neuron navigator 2 | 0.0353572 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0353387 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0350659 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0350024 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0342982 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0342287 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0341547 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0340824 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0337408 |
| NUP58 | nucleoporin 58 | 0.0332757 |
| GOLGA4 | golgin A4 | 0.0331341 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0330448 |
| OGA | O-GlcNAcase | 0.0329682 |
| SETD5 | SET domain containing 5 | 0.0328604 |
| PRELID2 | PRELI domain containing 2 | 0.032663 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0325464 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0323886 |
| RBM39 | RNA binding motif protein 39 | 0.0322943 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0322829 |
| NCAPG2 | non-SMC condensin II complex, subunit G2 | 0.0321319 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0321206 |
| FNIP1 | folliculin interacting protein 1 | 0.0319201 |
| CEP295 | centrosomal protein 295kDa | 0.0318993 |
| SMYD3 | SET and MYND domain containing 3 | 0.0317879 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0317853 |
| CEP250 | centrosomal protein 250kDa | 0.0317219 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0317107 |
| CKAP2L | cytoskeleton associated protein 2-like | 0.0317052 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0315074 |
| XPO1 | exportin 1 | 0.0314622 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0313516 |
| RAD51B | RAD51 paralog B | 0.0312333 |
| CASP4 | caspase 4, apoptosis-related cysteine peptidase | 0.0308069 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0306036 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0305446 |
| YBX3 | Y box binding protein 3 | 0.0303145 |
| MKI67 | marker of proliferation Ki-67 | 0.0301286 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0296636 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0296062 |
| CEP95 | centrosomal protein 95kDa | 0.0292441 |
| LDLR | low density lipoprotein receptor | 0.0291808 |
| CENPE | centromere protein E, 312kDa | 0.0291503 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.029096 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0289924 |
| DSCAM | Down syndrome cell adhesion molecule | 0.028939 |
| CLTC | clathrin, heavy chain (Hc) | 0.0288225 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.028578 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0284883 |
| ENO1 | enolase 1, (alpha) | 0.028412 |
| RBM33 | RNA binding motif protein 33 | 0.0283318 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0283217 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.130052 |
| HMGA2 | high mobility group AT-hook 2 | -0.0967932 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0949747 |
| INTS6 | integrator complex subunit 6 | -0.0861981 |
| TMSB10 | thymosin beta 10 | -0.0856037 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0634154 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0588683 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0587322 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0551777 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0533718 |
| PTMA | prothymosin, alpha | -0.0492864 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0491056 |
| MT2A | metallothionein 2A | -0.0471223 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0434336 |
| AEBP2 | AE binding protein 2 | -0.0414156 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0413923 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0411352 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.040999 |
| EGR1 | early growth response 1 | -0.0403444 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0392331 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0391166 |
| RPLP1 | ribosomal protein, large, P1 | -0.0390784 |
| SQSTM1 | sequestosome 1 | -0.038536 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.037505 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0374719 |
| RPL35A | ribosomal protein L35a | -0.0370481 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0366632 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0359627 |
| PODXL | podocalyxin-like | -0.0353336 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0350149 |
| IGF2 | insulin-like growth factor 2 | -0.0345523 |
| FUS | FUS RNA binding protein | -0.0341003 |
| GNAS | GNAS complex locus | -0.0337814 |
| FTL | ferritin, light polypeptide | -0.0335199 |
| PCED1B | PC-esterase domain containing 1B | -0.032565 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0318956 |
| ATG7 | autophagy related 7 | -0.0315749 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0314234 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0310669 |
| RAI14 | retinoic acid induced 14 | -0.0303597 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0303496 |
| COL5A1 | collagen, type V, alpha 1 | -0.0298789 |
| RPS13 | ribosomal protein S13 | -0.0297734 |
| RPS17 | ribosomal protein S17 | -0.0293695 |
| IER3 | immediate early response 3 | -0.0284237 |
| UBB | ubiquitin B | -0.0282799 |
| HLA-B | major histocompatibility complex, class I, B | -0.0279815 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.02758 |
| ANGPTL4 | angiopoietin-like 4 | -0.0275251 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0269482 |
| NLK | nemo-like kinase | -0.0267768 |
| SKI | SKI proto-oncogene | -0.0265658 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0263156 |
| RPS27A | ribosomal protein S27a | -0.0262847 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0260536 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | -0.0259904 |
| RPL37 | ribosomal protein L37 | -0.0255392 |
| PCNX4 | pecanex 4 | -0.0253715 |
| RAB1A | RAB1A, member RAS oncogene family | -0.02533 |
| RPL23 | ribosomal protein L23 | -0.0252699 |
| RPLP2 | ribosomal protein, large, P2 | -0.0244088 |
| RPL36 | ribosomal protein L36 | -0.0241733 |
| CDH4 | cadherin 4, type 1, R-cadherin (retinal) | -0.0237253 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0236413 |
| PRR16 | proline rich 16 | -0.0233969 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0232302 |
| AHNAK | AHNAK nucleoprotein | -0.023196 |
| RPL9 | ribosomal protein L9 | -0.0231589 |
| NRG1 | neuregulin 1 | -0.0231341 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.023058 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0229674 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.022824 |
| B2M | beta-2-microglobulin | -0.0224613 |
| JAZF1 | JAZF zinc finger 1 | -0.0224464 |
| RPS8 | ribosomal protein S8 | -0.022415 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | -0.0222804 |
| RPS3 | ribosomal protein S3 | -0.0222673 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0221109 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.02195 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0218631 |
| PRKCA | protein kinase C, alpha | -0.0216645 |
| RPL37A | ribosomal protein L37a | -0.0215884 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.021562 |
| RPL34 | ribosomal protein L34 | -0.021373 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0212862 |
| TTC19 | tetratricopeptide repeat domain 19 | -0.02126 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0211306 |
| ITGAV | integrin, alpha V | -0.0210892 |
| JUN | jun proto-oncogene | -0.0209809 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0209391 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0209252 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | -0.0208523 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0207031 |
| TLE4 | transducin-like enhancer of split 4 | -0.0205658 |
| EGFR | epidermal growth factor receptor | -0.0203661 |
| CANX | calnexin | -0.0203287 |
| PURA | purine-rich element binding protein A | -0.0200559 |
| CAVIN1 | caveolae associated protein 1 | -0.0200158 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0199671 |
| ETV6 | ets variant 6 | -0.0199607 |
