| Dataset | DeepCoverMOA Drug Mechanisms of Action |
| Category | proteomics |
| Type | drug perturbation |
| External Link | https://pubchem.ncbi.nlm.nih.gov/compound/60947 |
| Similar Terms | |
| Downloads & Tools |
200 proteins with high or low expression in Tirofiban relative to other proteins from the DeepCoverMOA Drug Mechanisms of Action dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IFT57 | intraflagellar transport 57 | 0.57 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | 0.52 |
| EYS | eyes shut homolog (Drosophila) | 0.51 |
| IP6K2 | inositol hexakisphosphate kinase 2 | 0.48 |
| MVB12B | multivesicular body subunit 12B | 0.45 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.45 |
| SH2B1 | SH2B adaptor protein 1 | 0.44 |
| LEPROTL1 | leptin receptor overlapping transcript-like 1 | 0.42 |
| MRPL33 | mitochondrial ribosomal protein L33 | 0.4 |
| PHLDB3 | pleckstrin homology-like domain, family B, member 3 | 0.39 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.39 |
| EEF2KMT | eukaryotic elongation factor 2 lysine methyltransferase | 0.38 |
| BACH1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1 | 0.38 |
| DMD | dystrophin | 0.38 |
| AAGAB | alpha- and gamma-adaptin binding protein | 0.37 |
| MITD1 | MIT, microtubule interacting and transport, domain containing 1 | 0.37 |
| HYLS1 | hydrolethalus syndrome 1 | 0.36 |
| METTL9 | methyltransferase like 9 | 0.35 |
| GPC4 | glypican 4 | 0.35 |
| NEURL4 | neuralized E3 ubiquitin protein ligase 4 | 0.34 |
| TCTN2 | tectonic family member 2 | 0.34 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.34 |
| PIK3C2B | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta | 0.33 |
| FLCN | folliculin | 0.33 |
| SERINC1 | serine incorporator 1 | 0.33 |
| SOCS2 | suppressor of cytokine signaling 2 | 0.32 |
| USP48 | ubiquitin specific peptidase 48 | 0.32 |
| DNASE1L1 | deoxyribonuclease I-like 1 | 0.32 |
| CCDC130 | coiled-coil domain containing 130 | 0.31 |
| HBA1 | hemoglobin, alpha 1 | 0.31 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.31 |
| ABITRAM | actin binding transcription modulator | 0.31 |
| KIAA1586 | KIAA1586 | 0.3 |
| CD99 | CD99 molecule | 0.3 |
| HOXA10 | homeobox A10 | 0.3 |
| UBL5 | ubiquitin-like 5 | 0.3 |
| WDR54 | WD repeat domain 54 | 0.3 |
| SERINC5 | serine incorporator 5 | 0.3 |
| EWSR1 | EWS RNA-binding protein 1 | 0.3 |
| AMPD1 | adenosine monophosphate deaminase 1 | 0.29 |
| TMEM104 | transmembrane protein 104 | 0.29 |
| PAQR4 | progestin and adipoQ receptor family member IV | 0.29 |
| ALKBH5 | AlkB family member 5, RNA demethylase | 0.29 |
| CEP112 | centrosomal protein 112kDa | 0.29 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.29 |
| KSR1 | kinase suppressor of ras 1 | 0.28 |
| SARDH | sarcosine dehydrogenase | 0.28 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | 0.28 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.28 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.28 |
| CCNE2 | cyclin E2 | 0.28 |
| SUCO | SUN domain containing ossification factor | 0.28 |
| DNAH6 | dynein, axonemal, heavy chain 6 | 0.28 |
| PARD6G | par-6 family cell polarity regulator gamma | 0.28 |
| RRAGB | Ras-related GTP binding B | 0.27 |
| FBXO31 | F-box protein 31 | 0.27 |
| FCF1 | FCF1 rRNA-processing protein | 0.27 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.27 |
| MAN2C1 | mannosidase, alpha, class 2C, member 1 | 0.26 |
| KIFC3 | kinesin family member C3 | 0.26 |
| METTL18 | methyltransferase like 18 | 0.26 |
| INO80B | INO80 complex subunit B | 0.25 |
| FOSL1 | FOS-like antigen 1 | 0.25 |
| NDUFS8 | NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) | 0.25 |
| AMZ2 | archaelysin family metallopeptidase 2 | 0.25 |
| PRXL2C | peroxiredoxin like 2C | 0.25 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.25 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C | 0.25 |
| KCTD21 | potassium channel tetramerization domain containing 21 | 0.25 |
| OTUD5 | OTU deubiquitinase 5 | 0.25 |
| CLCN2 | chloride channel, voltage-sensitive 2 | 0.25 |
| FCSK | fucose kinase | 0.24 |
| ENTPD7 | ectonucleoside triphosphate diphosphohydrolase 7 | 0.24 |
| GPBP1L1 | GC-rich promoter binding protein 1-like 1 | 0.24 |
| PPP1R37 | protein phosphatase 1, regulatory subunit 37 | 0.24 |
| PLXNA3 | plexin A3 | 0.24 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.24 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.24 |
| GFOD2 | glucose-fructose oxidoreductase domain containing 2 | 0.24 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.23 |
| ZNF16 | zinc finger protein 16 | 0.23 |
| MICB | MHC class I polypeptide-related sequence B | 0.23 |
| CD58 | CD58 molecule | 0.23 |
| CEP57 | centrosomal protein 57kDa | 0.23 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) | 0.23 |
| EIF2B4 | eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa | 0.23 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.23 |
| ARL8A | ADP-ribosylation factor-like 8A | 0.23 |
| HLCS | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) | 0.23 |
| SPC24 | SPC24, NDC80 kinetochore complex component | 0.22 |
| FBXO17 | F-box protein 17 | 0.22 |
| PPP1R2B | PPP1R2 family member B | 0.22 |
| DMWD | dystrophia myotonica, WD repeat containing | 0.22 |
| RNF14 | ring finger protein 14 | 0.22 |
| DNM1L | dynamin 1-like | 0.22 |
| CETN1 | centrin, EF-hand protein, 1 | 0.22 |
| GINS2 | GINS complex subunit 2 (Psf2 homolog) | 0.22 |
| ITPKA | inositol-trisphosphate 3-kinase A | 0.22 |
| FOXC1 | forkhead box C1 | 0.22 |
| AMD1 | adenosylmethionine decarboxylase 1 | 0.22 |
| Symbol | Name | Standardized Value |
|---|---|---|
| USP27X | ubiquitin specific peptidase 27, X-linked | -0.72 |
| ZFPM1 | zinc finger protein, FOG family member 1 | -0.68 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.6 |
| BBS1 | Bardet-Biedl syndrome 1 | -0.59 |
| ABHD4 | abhydrolase domain containing 4 | -0.59 |
| CLCN3 | chloride channel, voltage-sensitive 3 | -0.55 |
| PRPF40B | PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) | -0.53 |
| SIN3B | SIN3 transcription regulator family member B | -0.52 |
| PIP | prolactin-induced protein | -0.51 |
| LAGE3 | L antigen family, member 3 | -0.51 |
| SLC39A11 | solute carrier family 39, member 11 | -0.5 |
| PPP2R3A | protein phosphatase 2, regulatory subunit B'', alpha | -0.49 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.46 |
| SS18L1 | synovial sarcoma translocation gene on chromosome 18-like 1 | -0.44 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | -0.44 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 | -0.43 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.43 |
| RNF149 | ring finger protein 149 | -0.43 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.42 |
| RAD51B | RAD51 paralog B | -0.41 |
| UBTD1 | ubiquitin domain containing 1 | -0.4 |
| ARHGAP44 | Rho GTPase activating protein 44 | -0.39 |
| KDM4D | lysine (K)-specific demethylase 4D | -0.38 |
| ZNF280D | zinc finger protein 280D | -0.37 |
| CEP128 | centrosomal protein 128kDa | -0.35 |
| ARHGAP23 | Rho GTPase activating protein 23 | -0.34 |
| SPOP | speckle-type POZ protein | -0.34 |
| RBKS | ribokinase | -0.34 |
| AGFG2 | ArfGAP with FG repeats 2 | -0.33 |
| BSPRY | B-box and SPRY domain containing | -0.33 |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa | -0.33 |
| KMT2B | lysine (K)-specific methyltransferase 2B | -0.32 |
| ATXN7 | ataxin 7 | -0.32 |
| IRF5 | interferon regulatory factor 5 | -0.32 |
| MAPK14 | mitogen-activated protein kinase 14 | -0.31 |
| HRH1 | histamine receptor H1 | -0.31 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | -0.31 |
| EVI5 | ecotropic viral integration site 5 | -0.31 |
| DALRD3 | DALR anticodon binding domain containing 3 | -0.31 |
| MAD2L1BP | MAD2L1 binding protein | -0.31 |
| MREG | melanoregulin | -0.31 |
| PVR | poliovirus receptor | -0.31 |
| ZNF814 | zinc finger protein 814 | -0.31 |
| TRPM1 | transient receptor potential cation channel, subfamily M, member 1 | -0.31 |
| TPM2 | tropomyosin 2 (beta) | -0.3 |
| NPDC1 | neural proliferation, differentiation and control, 1 | -0.3 |
| SLC39A3 | solute carrier family 39 (zinc transporter), member 3 | -0.3 |
| ITPKC | inositol-trisphosphate 3-kinase C | -0.3 |
| ACTBL2 | actin, beta-like 2 | -0.29 |
| SAYSD1 | SAYSVFN motif domain containing 1 | -0.29 |
| TBC1D7 | TBC1 domain family, member 7 | -0.29 |
| VEZF1 | vascular endothelial zinc finger 1 | -0.28 |
| BCO2 | beta-carotene oxygenase 2 | -0.28 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | -0.28 |
| SLF2 | SMC5-SMC6 complex localization factor 2 | -0.28 |
| BAHCC1 | BAH domain and coiled-coil containing 1 | -0.28 |
| RBPJL | recombination signal binding protein for immunoglobulin kappa J region-like | -0.28 |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 | -0.27 |
| LSM10 | LSM10, U7 small nuclear RNA associated | -0.27 |
| CFAP410 | cilia and flagella associated protein 410 | -0.27 |
| TRIM44 | tripartite motif containing 44 | -0.27 |
| MLF1 | myeloid leukemia factor 1 | -0.26 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.26 |
| CUL9 | cullin 9 | -0.26 |
| ZNF639 | zinc finger protein 639 | -0.26 |
| UIMC1 | ubiquitin interaction motif containing 1 | -0.26 |
| TMCO3 | transmembrane and coiled-coil domains 3 | -0.26 |
| TTLL4 | tubulin tyrosine ligase-like family member 4 | -0.26 |
| GATD1 | glutamine amidotransferase class 1 domain containing 1 | -0.25 |
| MRFAP1 | Morf4 family associated protein 1 | -0.25 |
| RAB17 | RAB17, member RAS oncogene family | -0.25 |
| TXN2 | thioredoxin 2 | -0.25 |
| ALG14 | ALG14, UDP-N-acetylglucosaminyltransferase subunit | -0.25 |
| WRB | tryptophan rich basic protein | -0.25 |
| PCGF3 | polycomb group ring finger 3 | -0.25 |
| PEX13 | peroxisomal biogenesis factor 13 | -0.24 |
| SLC25A29 | solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 | -0.24 |
| PLCH1 | phospholipase C, eta 1 | -0.24 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | -0.24 |
| ZNF184 | zinc finger protein 184 | -0.24 |
| EXT1 | exostosin glycosyltransferase 1 | -0.24 |
| TDRKH | tudor and KH domain containing | -0.24 |
| MDM4 | MDM4, p53 regulator | -0.24 |
| GPATCH2L | G patch domain containing 2-like | -0.24 |
| RNFT2 | ring finger protein, transmembrane 2 | -0.24 |
| VIM | vimentin | -0.24 |
| RNASET2 | ribonuclease T2 | -0.24 |
| LMTK2 | lemur tyrosine kinase 2 | -0.24 |
| SCRN3 | secernin 3 | -0.24 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.23 |
| YOD1 | YOD1 deubiquitinase | -0.23 |
| FKBP1A | FK506 binding protein 1A, 12kDa | -0.23 |
| CIR1 | corepressor interacting with RBPJ, 1 | -0.23 |
| FUNDC2 | FUN14 domain containing 2 | -0.23 |
| AMOT | angiomotin | -0.23 |
| WDR47 | WD repeat domain 47 | -0.23 |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 | -0.23 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.23 |
| CCDC88C | coiled-coil domain containing 88C | -0.22 |
| ABAT | 4-aminobutyrate aminotransferase | -0.22 |
