| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tofacitinib (citrate) perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tofacitinib (citrate)_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.144344 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0879965 |
| PRKCA | protein kinase C, alpha | 0.0870405 |
| PLAT | plasminogen activator, tissue | 0.0830885 |
| LSAMP | limbic system-associated membrane protein | 0.0781711 |
| SMYD3 | SET and MYND domain containing 3 | 0.0762849 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0679608 |
| VEGFA | vascular endothelial growth factor A | 0.0662226 |
| ST6GALNAC3 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 | 0.0617313 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0590473 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0581339 |
| ENAH | enabled homolog (Drosophila) | 0.0573593 |
| BPTF | bromodomain PHD finger transcription factor | 0.0563909 |
| VMP1 | vacuole membrane protein 1 | 0.0552951 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0530626 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0527707 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0497441 |
| SEPTIN9 | septin 9 | 0.0491408 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.048959 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0484012 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0467343 |
| MSI2 | musashi RNA-binding protein 2 | 0.0466177 |
| TENM4 | teneurin transmembrane protein 4 | 0.0460573 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0459114 |
| FMN1 | formin 1 | 0.0456733 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0439022 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0436346 |
| AMOTL1 | angiomotin like 1 | 0.0431132 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0425926 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0424706 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0419128 |
| CRH | corticotropin releasing hormone | 0.040882 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0387644 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0371972 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0368647 |
| PCBP2 | poly(rC) binding protein 2 | 0.0368233 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0366609 |
| TCF12 | transcription factor 12 | 0.0366149 |
| ATXN1 | ataxin 1 | 0.0356226 |
| ATXN10 | ataxin 10 | 0.0354552 |
| ZNF638 | zinc finger protein 638 | 0.0347677 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0343379 |
| KLHL13 | kelch-like family member 13 | 0.0338612 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0334395 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0322407 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | 0.0316429 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0313621 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0310618 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | 0.0306675 |
| ATRNL1 | attractin-like 1 | 0.0305268 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0305042 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0304264 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0302156 |
| UNC5B | unc-5 homolog B (C. elegans) | 0.0297691 |
| CUX1 | cut-like homeobox 1 | 0.0293985 |
| HELZ | helicase with zinc finger | 0.0293902 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.029253 |
| CDK19 | cyclin-dependent kinase 19 | 0.0287446 |
| GSE1 | Gse1 coiled-coil protein | 0.028664 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | 0.0286563 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0284627 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0282484 |
| SIK2 | salt-inducible kinase 2 | 0.027749 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0277389 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0270884 |
| CCDC88A | coiled-coil domain containing 88A | 0.0267954 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0265073 |
| PTEN | phosphatase and tensin homolog | 0.0264929 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0264758 |
| RET | ret proto-oncogene | 0.0261825 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.026109 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0260657 |
| FLNB | filamin B, beta | 0.026045 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0258632 |
| MEF2A | myocyte enhancer factor 2A | 0.0258149 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0257225 |
| ERBIN | erbb2 interacting protein | 0.0256156 |
| RPS3 | ribosomal protein S3 | 0.0255961 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0254828 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0253536 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0250793 |
| EHBP1 | EH domain binding protein 1 | 0.0250482 |
| DIAPH2 | diaphanous-related formin 2 | 0.0248389 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0247609 |
| KCNIP4 | Kv channel interacting protein 4 | 0.0245435 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.02451 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0240253 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0239643 |
| DACH2 | dachshund family transcription factor 2 | 0.0234866 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.023467 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0234264 |
| NREP | neuronal regeneration related protein | 0.0233427 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0232501 |
| DNMBP | dynamin binding protein | 0.0230225 |
| TOX | thymocyte selection-associated high mobility group box | 0.0227669 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0227566 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0227364 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.022597 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0225274 |
| RAD51B | RAD51 paralog B | 0.0224146 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.362152 |
| IGF2 | insulin-like growth factor 2 | -0.19652 |
| COL3A1 | collagen, type III, alpha 1 | -0.109189 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0995663 |
| PTMA | prothymosin, alpha | -0.0851595 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0798275 |
| RNF213 | ring finger protein 213 | -0.0715545 |
| NRG1 | neuregulin 1 | -0.0699326 |
| RPL38 | ribosomal protein L38 | -0.0548046 |
| RIGI | RNA sensor RIG-I | -0.0521211 |
| SP100 | SP100 nuclear antigen | -0.0500613 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0492921 |
| SYT1 | synaptotagmin I | -0.0487637 |
| RPS24 | ribosomal protein S24 | -0.0482938 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0476053 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0475171 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0447211 |
| LMNA | lamin A/C | -0.044097 |
| VIM | vimentin | -0.0439072 |
| RPLP1 | ribosomal protein, large, P1 | -0.0422142 |
| MX2 | MX dynamin-like GTPase 2 | -0.0417712 |
| RPLP0 | ribosomal protein, large, P0 | -0.0415025 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.041307 |
| RPL19 | ribosomal protein L19 | -0.0399152 |
| TRIB2 | tribbles pseudokinase 2 | -0.0396616 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0391253 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0384225 |
| COL1A1 | collagen, type I, alpha 1 | -0.0383269 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0380902 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0376692 |
| CANX | calnexin | -0.03646 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0364436 |
| S100A6 | S100 calcium binding protein A6 | -0.0344525 |
| CCDC47 | coiled-coil domain containing 47 | -0.0340037 |
| NRP1 | neuropilin 1 | -0.0335618 |
| ANXA2 | annexin A2 | -0.0327617 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0327046 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0317722 |
| WDR45B | WD repeat domain 45B | -0.0310981 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0303602 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0299645 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0297647 |
| H3-3B | H3.3 histone B | -0.0291405 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0291295 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.028698 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0286471 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0283729 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0280732 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0275706 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0263072 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.0262148 |
| ACTG1 | actin gamma 1 | -0.0259621 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 | -0.0259371 |
| MX1 | MX dynamin-like GTPase 1 | -0.0257914 |
| ARF1 | ADP-ribosylation factor 1 | -0.0254313 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0252574 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0250632 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0248736 |
| CCND1 | cyclin D1 | -0.02486 |
| SPAG9 | sperm associated antigen 9 | -0.0248492 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0247998 |
| RBM39 | RNA binding motif protein 39 | -0.0247261 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0240829 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0236011 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0235642 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0233702 |
| RAB21 | RAB21, member RAS oncogene family | -0.0233581 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0232311 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0231669 |
| CD164 | CD164 molecule, sialomucin | -0.0227669 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0226635 |
| RPL36A | ribosomal protein L36a | -0.0225377 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0224893 |
| ZNF33A | zinc finger protein 33A | -0.0220239 |
| GDF15 | growth differentiation factor 15 | -0.0219749 |
| RPS29 | ribosomal protein S29 | -0.0218668 |
| RPL6 | ribosomal protein L6 | -0.0218416 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0217986 |
| GPC5 | glypican 5 | -0.0217541 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0216254 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0215376 |
| AOPEP | aminopeptidase O (putative) | -0.0215135 |
| RPL23 | ribosomal protein L23 | -0.0213536 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0213011 |
| IRS1 | insulin receptor substrate 1 | -0.0212914 |
| RPL32 | ribosomal protein L32 | -0.0212687 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0212111 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0211337 |
| NEK7 | NIMA-related kinase 7 | -0.0210584 |
| RPL4 | ribosomal protein L4 | -0.0207701 |
| RPL12 | ribosomal protein L12 | -0.0207486 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0206851 |
| UBC | ubiquitin C | -0.0205394 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.020428 |
| MAP1B | microtubule-associated protein 1B | -0.0204102 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0203969 |
| IER3 | immediate early response 3 | -0.0203605 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0203588 |
| AHNAK | AHNAK nucleoprotein | -0.0202961 |
| ZNF33B | zinc finger protein 33B | -0.0202022 |
