| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tofacitinib (citrate) perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tofacitinib (citrate)_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.146727 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0877531 |
| ITGA6 | integrin, alpha 6 | 0.086798 |
| VEGFA | vascular endothelial growth factor A | 0.0685554 |
| PHF3 | PHD finger protein 3 | 0.0551074 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0548563 |
| ABHD2 | abhydrolase domain containing 2 | 0.0547712 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0525604 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0505348 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0500357 |
| SEPTIN9 | septin 9 | 0.0465417 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0426845 |
| BCL2L1 | BCL2-like 1 | 0.0406231 |
| FTL | ferritin, light polypeptide | 0.040015 |
| FAT1 | FAT atypical cadherin 1 | 0.038834 |
| MLPH | melanophilin | 0.0388233 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0369762 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0364818 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.036037 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.035603 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0346736 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0343186 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0341811 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0339011 |
| NCOR2 | nuclear receptor corepressor 2 | 0.033772 |
| TRERF1 | transcriptional regulating factor 1 | 0.0334151 |
| TSC22D1 | TSC22 domain family, member 1 | 0.033085 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0327431 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0327149 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0322737 |
| DIAPH1 | diaphanous-related formin 1 | 0.0316673 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0307977 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0305723 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0299684 |
| MATR3 | matrin 3 | 0.0298821 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0297161 |
| JMJD1C | jumonji domain containing 1C | 0.0296777 |
| VMP1 | vacuole membrane protein 1 | 0.0296526 |
| RPS3 | ribosomal protein S3 | 0.029652 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0293992 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0289817 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0282508 |
| RPS6 | ribosomal protein S6 | 0.028228 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | 0.0280901 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0280303 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0280028 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0279236 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0279165 |
| KIF16B | kinesin family member 16B | 0.0258604 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0257702 |
| DSPP | dentin sialophosphoprotein | 0.0255843 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | 0.0254244 |
| MEF2A | myocyte enhancer factor 2A | 0.0247827 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0244982 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0244341 |
| VOPP1 | vesicular, overexpressed in cancer, prosurvival protein 1 | 0.0243025 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0242573 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0237726 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0236153 |
| CORIN | corin, serine peptidase | 0.0235968 |
| SLK | STE20-like kinase | 0.0235813 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0235461 |
| DNM2 | dynamin 2 | 0.0233099 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0231919 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0229546 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0227085 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.0225805 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0224952 |
| TPM3 | tropomyosin 3 | 0.0224834 |
| SH3PXD2A | SH3 and PX domains 2A | 0.0224081 |
| YAP1 | Yes-associated protein 1 | 0.0223425 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.022283 |
| KRT18 | keratin 18, type I | 0.021912 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0218947 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0209821 |
| UBAC2 | UBA domain containing 2 | 0.0209549 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | 0.0208691 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0205031 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0204994 |
| EZR | ezrin | 0.0202886 |
| ARGLU1 | arginine and glutamate rich 1 | 0.020268 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0202482 |
| PRSS22 | protease, serine, 22 | 0.0202215 |
| ATP9A | ATPase, class II, type 9A | 0.020208 |
| CDHR2 | cadherin-related family member 2 | 0.0201571 |
| RPL9 | ribosomal protein L9 | 0.0200857 |
| RPL37A | ribosomal protein L37a | 0.0199846 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0199568 |
| MAP7 | microtubule-associated protein 7 | 0.0199469 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0198757 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0198311 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0197949 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0197678 |
| FHL2 | four and a half LIM domains 2 | 0.0196093 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0195136 |
| RNF149 | ring finger protein 149 | 0.0194245 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0194125 |
| RPS17 | ribosomal protein S17 | 0.0193138 |
| RPL11 | ribosomal protein L11 | 0.0191544 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0191536 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.168674 |
| RNF213 | ring finger protein 213 | -0.152989 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.151548 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.130043 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.125212 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.110662 |
| INTS6 | integrator complex subunit 6 | -0.101308 |
| RIGI | RNA sensor RIG-I | -0.10115 |
| HLA-B | major histocompatibility complex, class I, B | -0.100735 |
| SQSTM1 | sequestosome 1 | -0.100209 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0897052 |
| SP100 | SP100 nuclear antigen | -0.083513 |
| LMO7 | LIM domain 7 | -0.0826468 |
| RUNX1 | runt-related transcription factor 1 | -0.0800783 |
| XAF1 | XIAP associated factor 1 | -0.0795855 |
| H1-0 | H1.0 linker histone | -0.072544 |
| MX2 | MX dynamin-like GTPase 2 | -0.0690288 |
| PLSCR1 | phospholipid scramblase 1 | -0.0688502 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0672249 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0656212 |
| MX1 | MX dynamin-like GTPase 1 | -0.0655445 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0638339 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0624953 |
| RRBP1 | ribosome binding protein 1 | -0.0589448 |
| HLA-E | major histocompatibility complex, class I, E | -0.05884 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0585051 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0582985 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0581441 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0572819 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0572667 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0546321 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0545979 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0507108 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0493236 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0489735 |
| HDLBP | high density lipoprotein binding protein | -0.0482923 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0478416 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0474418 |
| PERP | PERP, TP53 apoptosis effector | -0.0467319 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0462802 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0459797 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.045938 |
| PMP22 | peripheral myelin protein 22 | -0.0458497 |
| HLA-C | major histocompatibility complex, class I, C | -0.045849 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0449901 |
| ACTN4 | actinin, alpha 4 | -0.0446186 |
| RBM39 | RNA binding motif protein 39 | -0.0425879 |
| SDC4 | syndecan 4 | -0.0423882 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0421873 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.0418327 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0414814 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0414141 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0407283 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0390943 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0378771 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0375006 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0374213 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | -0.0370837 |
| FNDC3B | fibronectin type III domain containing 3B | -0.036918 |
| PTMA | prothymosin, alpha | -0.036737 |
| MECOM | MDS1 and EVI1 complex locus | -0.0366712 |
| SAMHD1 | SAM domain and HD domain 1 | -0.0366371 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0356604 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0356016 |
| MKI67 | marker of proliferation Ki-67 | -0.0354527 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0354382 |
| VCL | vinculin | -0.0350869 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0349732 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0347689 |
| ADIPOR2 | adiponectin receptor 2 | -0.0344234 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0343475 |
| JUN | jun proto-oncogene | -0.0338746 |
| NCKAP5 | NCK-associated protein 5 | -0.0337011 |
| BRCA2 | breast cancer 2, early onset | -0.0333277 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0332639 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0332597 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0331576 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.03308 |
| NABP1 | nucleic acid binding protein 1 | -0.0329891 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0328308 |
| GNAS | GNAS complex locus | -0.0327473 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0326518 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0325557 |
| SLC2A12 | solute carrier family 2 (facilitated glucose transporter), member 12 | -0.031884 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0317398 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.03173 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | -0.031503 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0313145 |
| B3GALT5 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5 | -0.031271 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0300596 |
| DIAPH3 | diaphanous-related formin 3 | -0.0297244 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0297101 |
| KLF6 | Kruppel-like factor 6 | -0.0294517 |
| SERINC5 | serine incorporator 5 | -0.0291342 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0290692 |
| ARF1 | ADP-ribosylation factor 1 | -0.0283699 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0282069 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0280999 |
| IRF1 | interferon regulatory factor 1 | -0.0280692 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.027735 |
