| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tofacitinib (citrate) perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tofacitinib (citrate)_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.145122 |
| MTSS1 | metastasis suppressor 1 | 0.0842249 |
| MSN | moesin | 0.0625914 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.061292 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0588596 |
| TGM2 | transglutaminase 2 | 0.0540659 |
| PODXL | podocalyxin-like | 0.0537005 |
| PCDH1 | protocadherin 1 | 0.0527691 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0508497 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0501071 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0491423 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0473087 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0456168 |
| INTS6 | integrator complex subunit 6 | 0.0440653 |
| B2M | beta-2-microglobulin | 0.0423176 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0417836 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0417132 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0416182 |
| VEGFA | vascular endothelial growth factor A | 0.0390551 |
| NAV2 | neuron navigator 2 | 0.0380605 |
| SEPTIN9 | septin 9 | 0.0365278 |
| CLIC4 | chloride intracellular channel 4 | 0.0350989 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0339261 |
| PLS3 | plastin 3 | 0.0339141 |
| PLXNA2 | plexin A2 | 0.0334436 |
| LUZP1 | leucine zipper protein 1 | 0.0323684 |
| RASAL2 | RAS protein activator like 2 | 0.0317892 |
| VMP1 | vacuole membrane protein 1 | 0.0317811 |
| SLK | STE20-like kinase | 0.0311497 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0307522 |
| UTRN | utrophin | 0.0302832 |
| DIAPH1 | diaphanous-related formin 1 | 0.029465 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0293406 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0286355 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0282014 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0279178 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0275646 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0273496 |
| RCOR1 | REST corepressor 1 | 0.0271813 |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 | 0.0271808 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0267286 |
| TPM3 | tropomyosin 3 | 0.026396 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0258066 |
| TSC22D1 | TSC22 domain family, member 1 | 0.024422 |
| MT1E | metallothionein 1E | 0.0243948 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.024394 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.024256 |
| MYOF | myoferlin | 0.0240002 |
| AMOTL1 | angiomotin like 1 | 0.0237543 |
| TXNIP | thioredoxin interacting protein | 0.023509 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.0234361 |
| MCL1 | myeloid cell leukemia 1 | 0.023433 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0234308 |
| CEP250 | centrosomal protein 250kDa | 0.0231939 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0228874 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.02284 |
| ATF4 | activating transcription factor 4 | 0.0227639 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0226289 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0226243 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0224374 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0223067 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0222913 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0222403 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0222269 |
| TJP1 | tight junction protein 1 | 0.0219951 |
| RNF217 | ring finger protein 217 | 0.0218708 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0216464 |
| LMO7 | LIM domain 7 | 0.0214847 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0214124 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0211262 |
| YBX1 | Y box binding protein 1 | 0.0209637 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.020804 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0206288 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0203358 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0202802 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0197078 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0196195 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0193461 |
| IPO7 | importin 7 | 0.019331 |
| ANO1 | anoctamin 1, calcium activated chloride channel | 0.0191676 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0191617 |
| LYST | lysosomal trafficking regulator | 0.0191458 |
| ANO6 | anoctamin 6 | 0.0191184 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0190814 |
| CDK17 | cyclin-dependent kinase 17 | 0.0190137 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.01896 |
| PTK2 | protein tyrosine kinase 2 | 0.0187182 |
| GPR176 | G protein-coupled receptor 176 | 0.0180716 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0179852 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0176882 |
| SQSTM1 | sequestosome 1 | 0.0172951 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | 0.0172813 |
| CTBP2 | C-terminal binding protein 2 | 0.0171185 |
| CORO2A | coronin, actin binding protein, 2A | 0.0170647 |
| ZNF185 | zinc finger protein 185 (LIM domain) | 0.0170491 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0169912 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0168731 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0168005 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.016771 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.016764 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.219908 |
| NDRG1 | N-myc downstream regulated 1 | -0.120753 |
| FLNB | filamin B, beta | -0.111363 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.110533 |
| TMSB10 | thymosin beta 10 | -0.0988426 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0847237 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0807102 |
| SULF1 | sulfatase 1 | -0.0666976 |
| PGK1 | phosphoglycerate kinase 1 | -0.0661738 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.065864 |
| GNAS | GNAS complex locus | -0.0652318 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.064522 |
| LMNA | lamin A/C | -0.058842 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0575213 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0568218 |
| RPS21 | ribosomal protein S21 | -0.0551254 |
| STC1 | stanniocalcin 1 | -0.0540476 |
| AHNAK | AHNAK nucleoprotein | -0.0519523 |
| PTMA | prothymosin, alpha | -0.0516332 |
| IGF2 | insulin-like growth factor 2 | -0.0467799 |
| RBM39 | RNA binding motif protein 39 | -0.0464217 |
| CANX | calnexin | -0.0453392 |
| KRT17 | keratin 17, type I | -0.0453037 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0439855 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0439006 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0433258 |
| TMSB4X | thymosin beta 4, X-linked | -0.0433139 |
| S100A10 | S100 calcium binding protein A10 | -0.0426185 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0421871 |
| ANLN | anillin, actin binding protein | -0.0421676 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0418227 |
| EMP1 | epithelial membrane protein 1 | -0.041111 |
| RPLP1 | ribosomal protein, large, P1 | -0.0399496 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0396471 |
| RPL34 | ribosomal protein L34 | -0.0394334 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0389514 |
| ENO1 | enolase 1, (alpha) | -0.0383643 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0375746 |
| CAVIN1 | caveolae associated protein 1 | -0.0373838 |
| C4BPB | complement component 4 binding protein, beta | -0.0372615 |
| S100A2 | S100 calcium binding protein A2 | -0.0366161 |
| S100A6 | S100 calcium binding protein A6 | -0.0356985 |
| OGA | O-GlcNAcase | -0.0353559 |
| NEK7 | NIMA-related kinase 7 | -0.0350346 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0349678 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0349403 |
| S100A4 | S100 calcium binding protein A4 | -0.0344529 |
| H1-0 | H1.0 linker histone | -0.0342517 |
| MORF4L2 | mortality factor 4 like 2 | -0.0341094 |
| TAGLN2 | transgelin 2 | -0.0338061 |
| IER3 | immediate early response 3 | -0.0334641 |
| RPS24 | ribosomal protein S24 | -0.0333122 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0327351 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0326653 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0325093 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0320288 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0318172 |
| MYO10 | myosin X | -0.031791 |
| RIGI | RNA sensor RIG-I | -0.031719 |
| HDLBP | high density lipoprotein binding protein | -0.0315189 |
| LDHA | lactate dehydrogenase A | -0.0311483 |
| RPLP2 | ribosomal protein, large, P2 | -0.0311297 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.031045 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0309898 |
| SDC4 | syndecan 4 | -0.0308242 |
| SEPTIN7 | septin 7 | -0.0307297 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0301571 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0300389 |
| CUL4B | cullin 4B | -0.030005 |
| SBF2 | SET binding factor 2 | -0.0299251 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0297111 |
| RPL27A | ribosomal protein L27a | -0.0296899 |
| EZR | ezrin | -0.029644 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0295195 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0294667 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0292253 |
| SYPL1 | synaptophysin-like 1 | -0.0289962 |
| PALLD | palladin, cytoskeletal associated protein | -0.0288635 |
| ARF1 | ADP-ribosylation factor 1 | -0.0288315 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0287535 |
| ASPH | aspartate beta-hydroxylase | -0.0286946 |
| GLG1 | golgi glycoprotein 1 | -0.0286598 |
| KLF6 | Kruppel-like factor 6 | -0.0285121 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0284807 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0283478 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0279991 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0278288 |
| SQLE | squalene epoxidase | -0.0273599 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0272534 |
| GOLGA4 | golgin A4 | -0.0270831 |
| FOXO1 | forkhead box O1 | -0.0266662 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.026575 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0258333 |
| S100A9 | S100 calcium binding protein A9 | -0.0257597 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0255627 |
| KIAA1217 | KIAA1217 | -0.0254667 |
| RLF | rearranged L-myc fusion | -0.0252063 |
| CD99 | CD99 molecule | -0.0245823 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0245726 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0245669 |
