| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tofacitinib (citrate) perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tofacitinib (citrate)_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NALF1 | NALCN channel auxiliary factor 1 | 0.12943 |
| CD44 | CD44 molecule (Indian blood group) | 0.127815 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.106466 |
| MT2A | metallothionein 2A | 0.0730157 |
| ENO1 | enolase 1, (alpha) | 0.0717864 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0672357 |
| B2M | beta-2-microglobulin | 0.0656977 |
| RHOA | ras homolog family member A | 0.0593975 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0558739 |
| SET | SET nuclear proto-oncogene | 0.0547009 |
| PODXL | podocalyxin-like | 0.0544726 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0542915 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0541597 |
| PTK2 | protein tyrosine kinase 2 | 0.0537429 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0518021 |
| SLC12A8 | solute carrier family 12, member 8 | 0.0500797 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0479053 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0463889 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0448152 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0442545 |
| CALR | calreticulin | 0.0433748 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0430233 |
| ERBIN | erbb2 interacting protein | 0.0428436 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0419956 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0415097 |
| TPM3 | tropomyosin 3 | 0.0414856 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0414378 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0403508 |
| RPS3 | ribosomal protein S3 | 0.0397872 |
| ZNF841 | zinc finger protein 841 | 0.0395736 |
| RAI14 | retinoic acid induced 14 | 0.039095 |
| POTEF | POTE ankyrin domain family, member F | 0.0389703 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.035909 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0357358 |
| VEGFA | vascular endothelial growth factor A | 0.0356718 |
| DST | dystonin | 0.0350893 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0349796 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | 0.0349058 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0346521 |
| AXL | AXL receptor tyrosine kinase | 0.0342612 |
| SMYD3 | SET and MYND domain containing 3 | 0.0341916 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0336785 |
| AOPEP | aminopeptidase O (putative) | 0.0334583 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0334274 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0332591 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0329067 |
| ANXA2 | annexin A2 | 0.0322481 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.032109 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0320209 |
| CORO1C | coronin, actin binding protein, 1C | 0.0304002 |
| PRIM2 | primase, DNA, polypeptide 2 (58kDa) | 0.0303356 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0300281 |
| CANX | calnexin | 0.0296348 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.0295608 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0294583 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0294084 |
| LDHA | lactate dehydrogenase A | 0.0293814 |
| RAD51B | RAD51 paralog B | 0.0289445 |
| ASPH | aspartate beta-hydroxylase | 0.0286463 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0284551 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0283158 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | 0.0281968 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0280237 |
| VCL | vinculin | 0.0280176 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0277733 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.027373 |
| NEK7 | NIMA-related kinase 7 | 0.0272633 |
| RPS2 | ribosomal protein S2 | 0.0268669 |
| MSN | moesin | 0.0267347 |
| RPL7 | ribosomal protein L7 | 0.0265081 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | 0.0263193 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0262493 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0261761 |
| CALU | calumenin | 0.0259799 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.0258157 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0256976 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0255846 |
| CDK17 | cyclin-dependent kinase 17 | 0.0255556 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0253028 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0252538 |
| SH3RF1 | SH3 domain containing ring finger 1 | 0.02518 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0251454 |
| BCL2L1 | BCL2-like 1 | 0.0251206 |
| ATG7 | autophagy related 7 | 0.0249242 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0248751 |
| VMP1 | vacuole membrane protein 1 | 0.0248642 |
| SERBP1 | SERPINE1 mRNA binding protein 1 | 0.0248115 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.0247872 |
| GLIS3 | GLIS family zinc finger 3 | 0.0246549 |
| TUBB4B | tubulin, beta 4B class IVb | 0.0243806 |
| RPS17 | ribosomal protein S17 | 0.0242781 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0240104 |
| AHNAK | AHNAK nucleoprotein | 0.0239404 |
| EXOC4 | exocyst complex component 4 | 0.0238198 |
| RANBP17 | RAN binding protein 17 | 0.0237288 |
| RACK1 | receptor for activated C kinase 1 | 0.0230188 |
| MLPH | melanophilin | 0.0229548 |
| APP | amyloid beta (A4) precursor protein | 0.0228913 |
| UTRN | utrophin | 0.0228789 |
| RPL9 | ribosomal protein L9 | 0.0228385 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.188197 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.166074 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.155991 |
| MT1X | metallothionein 1X | -0.155436 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.144965 |
| FN1 | fibronectin 1 | -0.135364 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.128263 |
| HLA-B | major histocompatibility complex, class I, B | -0.109505 |
| NDRG1 | N-myc downstream regulated 1 | -0.105698 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.102204 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.102106 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0958528 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0931448 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.085562 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0664077 |
| CTSD | cathepsin D | -0.0652599 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0640061 |
| ADM | adrenomedullin | -0.0607393 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0592966 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0571619 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0550506 |
| GNAS | GNAS complex locus | -0.0549579 |
| TMSB10 | thymosin beta 10 | -0.0549504 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0537336 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.049962 |
| PKM | pyruvate kinase, muscle | -0.0490217 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0477116 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.046437 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0460136 |
| DEK | DEK proto-oncogene | -0.0459007 |
| ZNF432 | zinc finger protein 432 | -0.0438561 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0432066 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0429767 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0410901 |
| AFAP1 | actin filament associated protein 1 | -0.0396395 |
| HLA-A | major histocompatibility complex, class I, A | -0.0383362 |
| CADM1 | cell adhesion molecule 1 | -0.0383104 |
| SUCO | SUN domain containing ossification factor | -0.0362118 |
| TGFB2 | transforming growth factor, beta 2 | -0.0359168 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0356053 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0347878 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0342518 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0341301 |
| RYBP | RING1 and YY1 binding protein | -0.033993 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.033593 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0335314 |
| RBM39 | RNA binding motif protein 39 | -0.0329335 |
| S100A6 | S100 calcium binding protein A6 | -0.0326715 |
| FOSL1 | FOS-like antigen 1 | -0.0318672 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0316782 |
| SNX14 | sorting nexin 14 | -0.0314688 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.031416 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0314001 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0312853 |
| USP3 | ubiquitin specific peptidase 3 | -0.0308673 |
| SULF1 | sulfatase 1 | -0.0308039 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0308031 |
| HMGB1 | high mobility group box 1 | -0.0307992 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0307586 |
| RPL27A | ribosomal protein L27a | -0.0307358 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0306524 |
| PFN1 | profilin 1 | -0.0301026 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0298789 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0297135 |
| TPD52 | tumor protein D52 | -0.0292245 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0287787 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0285601 |
| PRELID2 | PRELI domain containing 2 | -0.0283252 |
| PLIN2 | perilipin 2 | -0.0279884 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0279383 |
| RUNX1 | runt-related transcription factor 1 | -0.0278555 |
| EGFR | epidermal growth factor receptor | -0.0277295 |
| PGK1 | phosphoglycerate kinase 1 | -0.0275966 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0275942 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0273399 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0270366 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0268784 |
| SEPTIN7 | septin 7 | -0.0268627 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0267579 |
| JUN | jun proto-oncogene | -0.0265447 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0262993 |
| ZNF292 | zinc finger protein 292 | -0.0261917 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0261822 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0259094 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0258392 |
| INSIG1 | insulin induced gene 1 | -0.0253242 |
| TRPC4 | transient receptor potential cation channel, subfamily C, member 4 | -0.0253145 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | -0.025241 |
| SQSTM1 | sequestosome 1 | -0.0248402 |
| RTN4 | reticulon 4 | -0.0248213 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0243376 |
| MYOF | myoferlin | -0.024218 |
| MPZL1 | myelin protein zero-like 1 | -0.0241633 |
| SDC4 | syndecan 4 | -0.0240593 |
| PCBP2 | poly(rC) binding protein 2 | -0.0235264 |
| UBC | ubiquitin C | -0.0234415 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0233915 |
| CCNL1 | cyclin L1 | -0.0232578 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0231118 |
| TAPBP | TAP binding protein (tapasin) | -0.0229074 |
