| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tofacitinib (citrate) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tofacitinib (citrate)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0992599 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0866195 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0776614 |
| VCL | vinculin | 0.0747461 |
| TXNRD1 | thioredoxin reductase 1 | 0.0700316 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0639415 |
| RPS6 | ribosomal protein S6 | 0.0639002 |
| CD44 | CD44 molecule (Indian blood group) | 0.0628485 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0622202 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0620458 |
| HDAC9 | histone deacetylase 9 | 0.0613305 |
| HAS2 | hyaluronan synthase 2 | 0.0568206 |
| FRMD6 | FERM domain containing 6 | 0.0559346 |
| RUNX1 | runt-related transcription factor 1 | 0.054532 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0530853 |
| MSN | moesin | 0.0530708 |
| LSAMP | limbic system-associated membrane protein | 0.0515118 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0486682 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0484948 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0476068 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0472467 |
| CALD1 | caldesmon 1 | 0.0470093 |
| CDK17 | cyclin-dependent kinase 17 | 0.0459256 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0455423 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0427264 |
| LIMA1 | LIM domain and actin binding 1 | 0.0422294 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0398685 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0386625 |
| ITGA6 | integrin, alpha 6 | 0.0378606 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0378123 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0374841 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0374225 |
| NTM | neurotrimin | 0.0364296 |
| RPS18 | ribosomal protein S18 | 0.0358575 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | 0.0355022 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0350831 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0350464 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0343233 |
| RTN4 | reticulon 4 | 0.033935 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0325911 |
| DTNA | dystrobrevin, alpha | 0.0324464 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0318053 |
| ATP13A3 | ATPase type 13A3 | 0.0315285 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0314336 |
| NAV3 | neuron navigator 3 | 0.0310699 |
| MKI67 | marker of proliferation Ki-67 | 0.0306382 |
| JMJD1C | jumonji domain containing 1C | 0.0306157 |
| PAWR | PRKC, apoptosis, WT1, regulator | 0.0299582 |
| TXNIP | thioredoxin interacting protein | 0.0296312 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0291196 |
| RHOA | ras homolog family member A | 0.0289818 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0285827 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0281913 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0269486 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0268736 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.026749 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0267447 |
| RND3 | Rho family GTPase 3 | 0.02674 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.0267229 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0265155 |
| RPS2 | ribosomal protein S2 | 0.0261472 |
| FOSL1 | FOS-like antigen 1 | 0.0260307 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0258663 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | 0.0258548 |
| ENKUR | enkurin, TRPC channel interacting protein | 0.0249207 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0244752 |
| AXL | AXL receptor tyrosine kinase | 0.0235797 |
| ERBIN | erbb2 interacting protein | 0.0235004 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.023175 |
| TNNC1 | troponin C type 1 (slow) | 0.0230304 |
| BDNF | brain-derived neurotrophic factor | 0.0228915 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0227731 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0225135 |
| CASC3 | cancer susceptibility candidate 3 | 0.0224701 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0223819 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0220101 |
| TPM3 | tropomyosin 3 | 0.0219969 |
| TM4SF19 | transmembrane 4 L six family member 19 | 0.0219876 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0218646 |
| DNMBP | dynamin binding protein | 0.0218636 |
| MED13L | mediator complex subunit 13-like | 0.0217885 |
| RNF145 | ring finger protein 145 | 0.0217219 |
| LOXL2 | lysyl oxidase-like 2 | 0.0216928 |
| VMP1 | vacuole membrane protein 1 | 0.0214212 |
| RPS7 | ribosomal protein S7 | 0.0214111 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0212759 |
| RPL11 | ribosomal protein L11 | 0.0212057 |
| RPL26 | ribosomal protein L26 | 0.0210197 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0207134 |
| RPL3 | ribosomal protein L3 | 0.0206767 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0206464 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0205492 |
| SIK3 | SIK family kinase 3 | 0.0202938 |
| RPS3 | ribosomal protein S3 | 0.0200166 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0197273 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0193435 |
| CDK14 | cyclin-dependent kinase 14 | 0.0192011 |
| CENPF | centromere protein F, 350/400kDa | 0.0191044 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0187577 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0185189 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.216093 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.171504 |
| GPC6 | glypican 6 | -0.132748 |
| TMSB10 | thymosin beta 10 | -0.128742 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0956747 |
| CDH13 | cadherin 13 | -0.0903982 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0863648 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0816128 |
| ASPH | aspartate beta-hydroxylase | -0.0716753 |
| ACTG1 | actin gamma 1 | -0.0701549 |
| NDRG1 | N-myc downstream regulated 1 | -0.0688003 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0678974 |
| RPL23 | ribosomal protein L23 | -0.0675887 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0656081 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0630996 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0615448 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0611456 |
| UBC | ubiquitin C | -0.0610163 |
| RPS27A | ribosomal protein S27a | -0.0561582 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0558609 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0501188 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0500633 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0482589 |
| RIGI | RNA sensor RIG-I | -0.0467455 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0454867 |
| PTK2 | protein tyrosine kinase 2 | -0.0453125 |
| INTS6 | integrator complex subunit 6 | -0.0444064 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0435131 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | -0.0418776 |
| RPLP1 | ribosomal protein, large, P1 | -0.0415446 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0415029 |
| NAV1 | neuron navigator 1 | -0.0414881 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0397442 |
| PKM | pyruvate kinase, muscle | -0.0397294 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0396791 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0387467 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0384201 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.038036 |
| EFNA5 | ephrin-A5 | -0.0380031 |
| NABP1 | nucleic acid binding protein 1 | -0.0371659 |
| SP100 | SP100 nuclear antigen | -0.0371622 |
| PCBP2 | poly(rC) binding protein 2 | -0.0371621 |
| ZNF804A | zinc finger protein 804A | -0.0363756 |
| GNAS | GNAS complex locus | -0.036144 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0358872 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0353538 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0345297 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0339791 |
| KIAA1549L | KIAA1549-like | -0.0338631 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0334153 |
| STC1 | stanniocalcin 1 | -0.0329857 |
| RPL27A | ribosomal protein L27a | -0.0327856 |
| DNAJA1 | DnaJ (Hsp40) homolog, subfamily A, member 1 | -0.0319311 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0311076 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0302663 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0298358 |
| AHNAK | AHNAK nucleoprotein | -0.0295907 |
| PCDH9 | protocadherin 9 | -0.0291928 |
| RNF213 | ring finger protein 213 | -0.0291793 |
| TLE4 | transducin-like enhancer of split 4 | -0.0290094 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0285774 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0285736 |
| RPL8 | ribosomal protein L8 | -0.0285471 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0284467 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0279306 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0278658 |
| LASP1 | LIM and SH3 protein 1 | -0.027845 |
| RPLP2 | ribosomal protein, large, P2 | -0.0277665 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0275693 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0273766 |
| SEPTIN7 | septin 7 | -0.0273154 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0268118 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0266972 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0266447 |
| RPS24 | ribosomal protein S24 | -0.026624 |
| CAVIN1 | caveolae associated protein 1 | -0.0265975 |
| KIAA1217 | KIAA1217 | -0.0260087 |
| FTL | ferritin, light polypeptide | -0.0259638 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0257889 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0256258 |
| PRKCE | protein kinase C, epsilon | -0.0254523 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0250862 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0250741 |
| RPS19 | ribosomal protein S19 | -0.0247746 |
| MAP4 | microtubule-associated protein 4 | -0.0247706 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.024545 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.024531 |
| TAOK1 | TAO kinase 1 | -0.0242256 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0240739 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0236906 |
| MSR1 | macrophage scavenger receptor 1 | -0.0234787 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0232739 |
| PGK1 | phosphoglycerate kinase 1 | -0.0231848 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0228647 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0227933 |
| TMEM263 | transmembrane protein 263 | -0.0225665 |
| NBAS | neuroblastoma amplified sequence | -0.0224866 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0223197 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0221166 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0219498 |
