| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tofacitinib (citrate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tofacitinib (citrate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.217129 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.125874 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0936273 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0852052 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0799582 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0784108 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0745641 |
| RPS3 | ribosomal protein S3 | 0.0739123 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0734708 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0693801 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0693017 |
| VEGFA | vascular endothelial growth factor A | 0.066538 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0665166 |
| RPS12 | ribosomal protein S12 | 0.0593461 |
| ENO1 | enolase 1, (alpha) | 0.0557524 |
| RPS17 | ribosomal protein S17 | 0.0549329 |
| RPL37A | ribosomal protein L37a | 0.0534783 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | 0.0520227 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.050539 |
| EGR1 | early growth response 1 | 0.0501951 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0487014 |
| RPS2 | ribosomal protein S2 | 0.0477242 |
| RACK1 | receptor for activated C kinase 1 | 0.0470749 |
| SET | SET nuclear proto-oncogene | 0.0458415 |
| MCL1 | myeloid cell leukemia 1 | 0.0451066 |
| RPS8 | ribosomal protein S8 | 0.0447869 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0437736 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0437308 |
| RPS6 | ribosomal protein S6 | 0.0434184 |
| RPL9 | ribosomal protein L9 | 0.042463 |
| ANGPTL4 | angiopoietin-like 4 | 0.0423914 |
| PTK2 | protein tyrosine kinase 2 | 0.0408559 |
| HSPA8 | heat shock 70kDa protein 8 | 0.040323 |
| TPM3 | tropomyosin 3 | 0.0393526 |
| MSN | moesin | 0.0390244 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0379173 |
| RPL11 | ribosomal protein L11 | 0.0371433 |
| DSTN | destrin (actin depolymerizing factor) | 0.0366803 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0362869 |
| LDHA | lactate dehydrogenase A | 0.036246 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0359465 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0357089 |
| PLEKHG2 | pleckstrin homology domain containing, family G (with RhoGef domain) member 2 | 0.0350532 |
| ZNF146 | zinc finger protein 146 | 0.0349173 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0342934 |
| SESN2 | sestrin 2 | 0.0342442 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0339909 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0334258 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0332902 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0322889 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0322242 |
| RNF220 | ring finger protein 220 | 0.031039 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0303074 |
| CARS1 | cysteinyl-tRNA synthetase 1 | 0.0298058 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0292172 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0289611 |
| PAF1 | Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae) | 0.028911 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0288641 |
| RPS7 | ribosomal protein S7 | 0.0288028 |
| FTL | ferritin, light polypeptide | 0.0286827 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0283595 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0282508 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0280425 |
| HPCAL1 | hippocalcin-like 1 | 0.0276925 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0274083 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0273994 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0273398 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0269658 |
| RPS27A | ribosomal protein S27a | 0.0267281 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0265572 |
| RPL26 | ribosomal protein L26 | 0.0264216 |
| RPS18 | ribosomal protein S18 | 0.0260009 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0255796 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.025076 |
| SMYD3 | SET and MYND domain containing 3 | 0.0250748 |
| YBX1 | Y box binding protein 1 | 0.025054 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0245842 |
| SLK | STE20-like kinase | 0.0245024 |
| B2M | beta-2-microglobulin | 0.0243359 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0242908 |
| RPL7 | ribosomal protein L7 | 0.0238478 |
| CALCOCO2 | calcium binding and coiled-coil domain 2 | 0.023522 |
| CTTN | cortactin | 0.0235178 |
| MATR3 | matrin 3 | 0.0233535 |
| RHOA | ras homolog family member A | 0.0230957 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0228103 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.022709 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0226011 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0224236 |
| RPL7A | ribosomal protein L7a | 0.0223284 |
| ZFP36 | ZFP36 ring finger protein | 0.0222718 |
| RPS25 | ribosomal protein S25 | 0.0220604 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0218539 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0217474 |
| FOSL1 | FOS-like antigen 1 | 0.0216655 |
| RPL31 | ribosomal protein L31 | 0.0216566 |
| DKC1 | dyskeratosis congenita 1, dyskerin | 0.0215654 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0212285 |
| RPS13 | ribosomal protein S13 | 0.0207015 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0205029 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.171662 |
| TMSB10 | thymosin beta 10 | -0.124506 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.10773 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.104894 |
| ACTN4 | actinin, alpha 4 | -0.102217 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0944675 |
| AHNAK | AHNAK nucleoprotein | -0.0929544 |
| PTMA | prothymosin, alpha | -0.0851389 |
| TMEM123 | transmembrane protein 123 | -0.0717616 |
| SPAG9 | sperm associated antigen 9 | -0.0679176 |
| S100A6 | S100 calcium binding protein A6 | -0.0628285 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0613194 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0594657 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0582107 |
| MYOF | myoferlin | -0.0542458 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0495791 |
| RPS16 | ribosomal protein S16 | -0.0477988 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0463155 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0462847 |
| SNX14 | sorting nexin 14 | -0.045439 |
| ATP13A3 | ATPase type 13A3 | -0.0446396 |
| ANXA2 | annexin A2 | -0.0435553 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0432621 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0427407 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0425326 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0418106 |
| CD59 | CD59 molecule, complement regulatory protein | -0.0412814 |
| MORF4L2 | mortality factor 4 like 2 | -0.0411194 |
| COL18A1 | collagen, type XVIII, alpha 1 | -0.0410359 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0396468 |
| SLC38A2 | solute carrier family 38, member 2 | -0.039544 |
| LMNA | lamin A/C | -0.0390775 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0388978 |
| TAOK1 | TAO kinase 1 | -0.0387911 |
| UBAP2 | ubiquitin associated protein 2 | -0.0373799 |
| FMNL2 | formin-like 2 | -0.0372246 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0370946 |
| NF1 | neurofibromin 1 | -0.0368691 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0365436 |
| ANLN | anillin, actin binding protein | -0.0364359 |
| EFNA5 | ephrin-A5 | -0.0363285 |
| KLF6 | Kruppel-like factor 6 | -0.0354274 |
| H1-0 | H1.0 linker histone | -0.035126 |
| FRMD5 | FERM domain containing 5 | -0.0350003 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0344314 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0337613 |
| CTSD | cathepsin D | -0.0335301 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0331112 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0326515 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.032611 |
| ZNF217 | zinc finger protein 217 | -0.0305746 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.0303974 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0303577 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0297094 |
| OGA | O-GlcNAcase | -0.0292046 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0291854 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0288121 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0287888 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0287104 |
| ATF6 | activating transcription factor 6 | -0.0286151 |
| WDR45B | WD repeat domain 45B | -0.0285801 |
| SHTN1 | shootin 1 | -0.0282668 |
| WASF2 | WAS protein family, member 2 | -0.0276956 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0276825 |
| RPL28 | ribosomal protein L28 | -0.0274586 |
| MARF1 | meiosis regulator and mRNA stability factor 1 | -0.0274396 |
| INTS6 | integrator complex subunit 6 | -0.0271655 |
| VCL | vinculin | -0.026946 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0268704 |
| ACTG1 | actin gamma 1 | -0.0268497 |
| HMGB1 | high mobility group box 1 | -0.0267916 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.026586 |
| TPX2 | TPX2, microtubule-associated | -0.0264017 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0262417 |
| TUBB | tubulin, beta class I | -0.026104 |
| RBM39 | RNA binding motif protein 39 | -0.0260272 |
| BSG | basigin (Ok blood group) | -0.0259628 |
| SUCO | SUN domain containing ossification factor | -0.0257178 |
| CAVIN1 | caveolae associated protein 1 | -0.0255846 |
| MEF2A | myocyte enhancer factor 2A | -0.0255826 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0253991 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0251421 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.024982 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0249105 |
| RIGI | RNA sensor RIG-I | -0.0245937 |
| HMGA2 | high mobility group AT-hook 2 | -0.0243547 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0242411 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0242329 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0241458 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0240146 |
| CCND1 | cyclin D1 | -0.0239839 |
| FLNB | filamin B, beta | -0.0238982 |
| EIF2AK1 | eukaryotic translation initiation factor 2-alpha kinase 1 | -0.0237556 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0235938 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0235484 |
| DST | dystonin | -0.0235209 |
| NABP1 | nucleic acid binding protein 1 | -0.0231063 |
| PERP | PERP, TP53 apoptosis effector | -0.0230826 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0230431 |
| USP15 | ubiquitin specific peptidase 15 | -0.0230328 |
