| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tofacitinib (citrate) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tofacitinib (citrate)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.139692 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.073317 |
| VEGFA | vascular endothelial growth factor A | 0.0658531 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0563032 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0559556 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0510761 |
| KRT18 | keratin 18, type I | 0.0457191 |
| RPS18 | ribosomal protein S18 | 0.0445083 |
| MYO6 | myosin VI | 0.0423311 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0421744 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0416883 |
| DSPP | dentin sialophosphoprotein | 0.0412129 |
| EZR | ezrin | 0.0381304 |
| RPS12 | ribosomal protein S12 | 0.037744 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0371396 |
| RPS3 | ribosomal protein S3 | 0.0365228 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0361909 |
| TXNIP | thioredoxin interacting protein | 0.0349516 |
| RPS6 | ribosomal protein S6 | 0.0348323 |
| LAMC2 | laminin, gamma 2 | 0.0340371 |
| TPM3 | tropomyosin 3 | 0.0336001 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0329887 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0326321 |
| PCDH1 | protocadherin 1 | 0.0323078 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0322485 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0318722 |
| RPL26 | ribosomal protein L26 | 0.0317472 |
| ITGA6 | integrin, alpha 6 | 0.0309896 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0297784 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0295953 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0287391 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0287235 |
| TGM2 | transglutaminase 2 | 0.0286912 |
| SNX9 | sorting nexin 9 | 0.0285857 |
| GOLGA4 | golgin A4 | 0.0285724 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.028519 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.028271 |
| RPS2 | ribosomal protein S2 | 0.0274131 |
| CD47 | CD47 molecule | 0.0273794 |
| PARD3 | par-3 family cell polarity regulator | 0.0273679 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0269541 |
| MYO5B | myosin VB | 0.0268572 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0266907 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0258136 |
| RPS7 | ribosomal protein S7 | 0.0256232 |
| TMF1 | TATA element modulatory factor 1 | 0.0253744 |
| OSMR | oncostatin M receptor | 0.0251564 |
| JMJD1C | jumonji domain containing 1C | 0.0248834 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0248288 |
| RASA2 | RAS p21 protein activator 2 | 0.0248258 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0246991 |
| TJP2 | tight junction protein 2 | 0.0246621 |
| VMP1 | vacuole membrane protein 1 | 0.0246458 |
| RPL9 | ribosomal protein L9 | 0.0241358 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0241161 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0241082 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0240927 |
| BCL2L1 | BCL2-like 1 | 0.0236383 |
| RASAL2 | RAS protein activator like 2 | 0.0235927 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0233116 |
| MATR3 | matrin 3 | 0.0230107 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0225309 |
| RPS17 | ribosomal protein S17 | 0.0225226 |
| RAD51B | RAD51 paralog B | 0.022475 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0222721 |
| DIAPH1 | diaphanous-related formin 1 | 0.0221646 |
| MYEOV | myeloma overexpressed | 0.0220884 |
| CALR | calreticulin | 0.0215411 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0214812 |
| OPTN | optineurin | 0.021294 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0211327 |
| PNN | pinin, desmosome associated protein | 0.0210914 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0208084 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | 0.0202297 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0196944 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0195719 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0194681 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0193139 |
| NRP1 | neuropilin 1 | 0.0192997 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0190025 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0189769 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0189242 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0188007 |
| ANXA11 | annexin A11 | 0.018752 |
| CCNY | cyclin Y | 0.0186356 |
| SBNO2 | strawberry notch homolog 2 (Drosophila) | 0.0186241 |
| TCF12 | transcription factor 12 | 0.0185848 |
| CARD11 | caspase recruitment domain family, member 11 | 0.0185018 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0184028 |
| RHOA | ras homolog family member A | 0.0182457 |
| F11R | F11 receptor | 0.0181537 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | 0.0177501 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0176967 |
| RPL11 | ribosomal protein L11 | 0.0175684 |
| IGF2 | insulin-like growth factor 2 | 0.0175186 |
| ACTG1 | actin gamma 1 | 0.0172057 |
| RPL37 | ribosomal protein L37 | 0.0171909 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0168665 |
| SMAD3 | SMAD family member 3 | 0.0168111 |
| WDR43 | WD repeat domain 43 | 0.016694 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.323894 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.109747 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.107596 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0932686 |
| TMSB10 | thymosin beta 10 | -0.0880543 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0858403 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0851355 |
| SQSTM1 | sequestosome 1 | -0.0808724 |
| LMO7 | LIM domain 7 | -0.0787543 |
| RPLP1 | ribosomal protein, large, P1 | -0.0667046 |
| AHNAK | AHNAK nucleoprotein | -0.0635369 |
| RNF213 | ring finger protein 213 | -0.0629633 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0604194 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0600489 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0587605 |
| INTS6 | integrator complex subunit 6 | -0.0585647 |
| HLA-B | major histocompatibility complex, class I, B | -0.0576495 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0571813 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0556946 |
| ANXA2 | annexin A2 | -0.0547462 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0543336 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0511851 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0493488 |
| ANLN | anillin, actin binding protein | -0.04919 |
| RPL19 | ribosomal protein L19 | -0.048653 |
| GNAS | GNAS complex locus | -0.0486343 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0478158 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.04572 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0453941 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0445127 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0445061 |
| HMGB1 | high mobility group box 1 | -0.0441846 |
| S100A6 | S100 calcium binding protein A6 | -0.043193 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0427353 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0426743 |
| MKI67 | marker of proliferation Ki-67 | -0.042508 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0424413 |
| DSG2 | desmoglein 2 | -0.0421032 |
| ACTN4 | actinin, alpha 4 | -0.0419246 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0416912 |
| H1-0 | H1.0 linker histone | -0.0414559 |
| SDC4 | syndecan 4 | -0.0409869 |
| PTMA | prothymosin, alpha | -0.0406558 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0403277 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0397378 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0393961 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0393081 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.039288 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0390672 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0389134 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0385224 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0385189 |
| RPS19 | ribosomal protein S19 | -0.0382657 |
| TMEM123 | transmembrane protein 123 | -0.0378435 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0374931 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.037 |
| MT2A | metallothionein 2A | -0.0363455 |
| RPL34 | ribosomal protein L34 | -0.0362437 |
| HLA-C | major histocompatibility complex, class I, C | -0.0361816 |
| EGR1 | early growth response 1 | -0.0359155 |
| TXNRD1 | thioredoxin reductase 1 | -0.0356801 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0356298 |
| RIOK3 | RIO kinase 3 | -0.0356247 |
| FOSL1 | FOS-like antigen 1 | -0.0353017 |
| FN1 | fibronectin 1 | -0.0352292 |
| CD2AP | CD2-associated protein | -0.0350356 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0349377 |
| C3 | complement component 3 | -0.0344664 |
| RBM39 | RNA binding motif protein 39 | -0.0341899 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.033496 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0333193 |
| SP100 | SP100 nuclear antigen | -0.0332035 |
| VCL | vinculin | -0.0330125 |
| RIGI | RNA sensor RIG-I | -0.0326719 |
| TFRC | transferrin receptor | -0.0323722 |
| RYBP | RING1 and YY1 binding protein | -0.0323531 |
| MYOF | myoferlin | -0.0322861 |
| SPAG9 | sperm associated antigen 9 | -0.0322195 |
| ANKRD10 | ankyrin repeat domain 10 | -0.032117 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.031634 |
| RPS24 | ribosomal protein S24 | -0.0313794 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0309997 |
| S100A10 | S100 calcium binding protein A10 | -0.0305006 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0302331 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0300754 |
| TAOK1 | TAO kinase 1 | -0.0300021 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0299561 |
| HLA-E | major histocompatibility complex, class I, E | -0.0298786 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0298428 |
| MUC4 | mucin 4, cell surface associated | -0.0295511 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.029476 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0294701 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0291758 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0288875 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0287347 |
| RPL23 | ribosomal protein L23 | -0.028567 |
| MORF4L2 | mortality factor 4 like 2 | -0.028352 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0283519 |
| CENPF | centromere protein F, 350/400kDa | -0.028345 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0282582 |
