| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tofacitinib (citrate) perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tofacitinib (citrate)_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| BMP10 | bone morphogenetic protein 10 | 0.0633507 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0473815 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0421909 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0400812 |
| ENO1 | enolase 1, (alpha) | 0.0384459 |
| VCL | vinculin | 0.0364839 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0341199 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0325349 |
| ANKRD36B | ankyrin repeat domain 36B | 0.0324242 |
| GLI3 | GLI family zinc finger 3 | 0.0302266 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0298848 |
| RHOA | ras homolog family member A | 0.0298428 |
| AHNAK | AHNAK nucleoprotein | 0.0291145 |
| TPM4 | tropomyosin 4 | 0.0287403 |
| UNC13A | unc-13 homolog A (C. elegans) | 0.0277562 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0275397 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0272412 |
| AMOTL2 | angiomotin like 2 | 0.0272021 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0262893 |
| MYO5C | myosin VC | 0.0262537 |
| GLI2 | GLI family zinc finger 2 | 0.0260336 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0259528 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0255394 |
| KAT6A | K(lysine) acetyltransferase 6A | 0.0252366 |
| MKI67 | marker of proliferation Ki-67 | 0.0240597 |
| RLF | rearranged L-myc fusion | 0.0238312 |
| LOXL3 | lysyl oxidase-like 3 | 0.0237501 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.023452 |
| TMSB4X | thymosin beta 4, X-linked | 0.0232474 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0223444 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.0221101 |
| ZNF438 | zinc finger protein 438 | 0.0220303 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0214988 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0213372 |
| RPS18 | ribosomal protein S18 | 0.0209915 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0205607 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0203573 |
| SPRY2 | sprouty homolog 2 (Drosophila) | 0.0199887 |
| SOGA1 | suppressor of glucose, autophagy associated 1 | 0.0199075 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0198787 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0189429 |
| WWOX | WW domain containing oxidoreductase | 0.0188353 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0187747 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0187591 |
| KIF5B | kinesin family member 5B | 0.0187568 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0187348 |
| MACROD2 | MACRO domain containing 2 | 0.0187063 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0184124 |
| HDGF | hepatoma-derived growth factor | 0.0183321 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0182975 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0181458 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.017922 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | 0.017757 |
| CSNK1D | casein kinase 1, delta | 0.0174239 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0174077 |
| JUN | jun proto-oncogene | 0.0171132 |
| ITGA10 | integrin, alpha 10 | 0.016661 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0166174 |
| VPS26A | vacuolar protein sorting 26 homolog A (S. pombe) | 0.0165777 |
| PDCD6IP | programmed cell death 6 interacting protein | 0.0162499 |
| PAICS | phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase | 0.0162185 |
| APP | amyloid beta (A4) precursor protein | 0.0161985 |
| RPS3A | ribosomal protein S3A | 0.0158979 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0157832 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0156262 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 0.0155048 |
| CEP112 | centrosomal protein 112kDa | 0.0154994 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0154236 |
| CENPF | centromere protein F, 350/400kDa | 0.0152707 |
| TRIOBP | TRIO and F-actin binding protein | 0.0151851 |
| NAT10 | N-acetyltransferase 10 (GCN5-related) | 0.0151025 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | 0.015096 |
| GSE1 | Gse1 coiled-coil protein | 0.0150226 |
| MATR3 | matrin 3 | 0.0149344 |
| RTN4 | reticulon 4 | 0.0149072 |
| UCK2 | uridine-cytidine kinase 2 | 0.0148154 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0148028 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 0.0148026 |
| BCL2L1 | BCL2-like 1 | 0.0147013 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.0146998 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0146804 |
| SRSF4 | serine/arginine-rich splicing factor 4 | 0.0146618 |
| YTHDC1 | YTH domain containing 1 | 0.0144884 |
| CNTLN | centlein, centrosomal protein | 0.0144452 |
| GANAB | glucosidase, alpha; neutral AB | 0.0144395 |
| TNPO3 | transportin 3 | 0.0143241 |
| RBBP7 | retinoblastoma binding protein 7 | 0.0142951 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0142534 |
| FOXN2 | forkhead box N2 | 0.0142024 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0141961 |
| NAV2 | neuron navigator 2 | 0.0141433 |
| DUSP6 | dual specificity phosphatase 6 | 0.0139793 |
| RIOK3 | RIO kinase 3 | 0.0137971 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0137351 |
| DDI2 | DNA-damage inducible 1 homolog 2 (S. cerevisiae) | 0.0137286 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.0137092 |
| ZNF462 | zinc finger protein 462 | 0.0136034 |
| CTDSPL2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 | 0.0135774 |
| TBCD | tubulin folding cofactor D | 0.013561 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0134199 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.205581 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.134607 |
| PTMA | prothymosin, alpha | -0.111447 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0951943 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0909719 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0852514 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0679506 |
| FLNB | filamin B, beta | -0.0667257 |
| RBM39 | RNA binding motif protein 39 | -0.0637214 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0602536 |
| S100A6 | S100 calcium binding protein A6 | -0.0591777 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0575402 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0565648 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0565502 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0540207 |
| TXNRD1 | thioredoxin reductase 1 | -0.0530212 |
| RPL23 | ribosomal protein L23 | -0.0527306 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0509349 |
| ACTG1 | actin gamma 1 | -0.0498354 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0493133 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0491251 |
| ANK2 | ankyrin 2, neuronal | -0.0484224 |
| RPL35A | ribosomal protein L35a | -0.0483819 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0463562 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0457005 |
| RPS19 | ribosomal protein S19 | -0.0453717 |
| GOLGA4 | golgin A4 | -0.0410147 |
| EGFR | epidermal growth factor receptor | -0.0394714 |
| RPL37A | ribosomal protein L37a | -0.0390399 |
| RPL12 | ribosomal protein L12 | -0.0379743 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0371701 |
| RPL19 | ribosomal protein L19 | -0.0362801 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0361536 |
| RPL34 | ribosomal protein L34 | -0.0353548 |
| RPS8 | ribosomal protein S8 | -0.0348671 |
| RPS21 | ribosomal protein S21 | -0.0344588 |
| FTL | ferritin, light polypeptide | -0.0338707 |
| RRBP1 | ribosome binding protein 1 | -0.0335456 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0330702 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0330383 |
| RPLP2 | ribosomal protein, large, P2 | -0.0325873 |
| ECT2 | epithelial cell transforming 2 | -0.0322741 |
| TMEM65 | transmembrane protein 65 | -0.031278 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0307685 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0303501 |
| ZNF608 | zinc finger protein 608 | -0.0302677 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0294393 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0293717 |
| THOC2 | THO complex 2 | -0.0293644 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0290893 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.0284802 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0282432 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0276593 |
| TMSB10 | thymosin beta 10 | -0.0276526 |
| CCND1 | cyclin D1 | -0.0272879 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0272644 |
| RPL32 | ribosomal protein L32 | -0.0271168 |
| RPL18 | ribosomal protein L18 | -0.0270871 |
| PTEN | phosphatase and tensin homolog | -0.026987 |
| MEIS2 | Meis homeobox 2 | -0.0267902 |
| PFN1 | profilin 1 | -0.02669 |
| RPS24 | ribosomal protein S24 | -0.0266222 |
| LDHA | lactate dehydrogenase A | -0.0264914 |
| NEMF | nuclear export mediator factor | -0.0264418 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.0263908 |
| RPLP1 | ribosomal protein, large, P1 | -0.0262539 |
| RPS23 | ribosomal protein S23 | -0.0260731 |
| SEC63 | SEC63 homolog (S. cerevisiae) | -0.0260258 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0260178 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0259485 |
| ASPH | aspartate beta-hydroxylase | -0.025866 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0257865 |
| CLINT1 | clathrin interactor 1 | -0.0257818 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0257208 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0255745 |
| TJP1 | tight junction protein 1 | -0.0254422 |
| COG5 | component of oligomeric golgi complex 5 | -0.0254082 |
| RPL36 | ribosomal protein L36 | -0.0254037 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0253409 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0250127 |
| GOLGB1 | golgin B1 | -0.0248817 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0247853 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0247412 |
| CALR | calreticulin | -0.0246877 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0244764 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | -0.0244199 |
| TRIM24 | tripartite motif containing 24 | -0.0244076 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.024344 |
| FNIP1 | folliculin interacting protein 1 | -0.0243361 |
| RHBDD1 | rhomboid domain containing 1 | -0.0242889 |
| COPA | coatomer protein complex, subunit alpha | -0.0242885 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0242801 |
| NF1 | neurofibromin 1 | -0.0238906 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0238405 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0238247 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0237149 |
| RPS11 | ribosomal protein S11 | -0.0237019 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0236827 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.0235692 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.023555 |
