| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tofacitinib (citrate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tofacitinib (citrate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.19028 |
| CD44 | CD44 molecule (Indian blood group) | 0.157252 |
| VEGFA | vascular endothelial growth factor A | 0.120307 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0858819 |
| ENO1 | enolase 1, (alpha) | 0.0719113 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0624499 |
| MSN | moesin | 0.060456 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | 0.0569949 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0551543 |
| MLPH | melanophilin | 0.0531435 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0521056 |
| CDH13 | cadherin 13 | 0.0500242 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0497653 |
| GLIS3 | GLIS family zinc finger 3 | 0.0497017 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0486391 |
| B2M | beta-2-microglobulin | 0.0484695 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0468087 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0466403 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0462275 |
| VMP1 | vacuole membrane protein 1 | 0.0453831 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0440865 |
| SMYD3 | SET and MYND domain containing 3 | 0.0426837 |
| RASAL2 | RAS protein activator like 2 | 0.0425178 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.042324 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0400104 |
| CALR | calreticulin | 0.0395279 |
| CDCP1 | CUB domain containing protein 1 | 0.0385991 |
| JMJD1C | jumonji domain containing 1C | 0.0384988 |
| AHNAK | AHNAK nucleoprotein | 0.0374995 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0374094 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0365145 |
| UTRN | utrophin | 0.0355653 |
| ATXN1 | ataxin 1 | 0.0352852 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0345527 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.034311 |
| CEP250 | centrosomal protein 250kDa | 0.0342374 |
| STC1 | stanniocalcin 1 | 0.0341213 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0335303 |
| RAI14 | retinoic acid induced 14 | 0.0335204 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0325762 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0314184 |
| APP | amyloid beta (A4) precursor protein | 0.0313021 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0312442 |
| MYO10 | myosin X | 0.0312061 |
| EHBP1 | EH domain binding protein 1 | 0.0307834 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0299626 |
| RASA3 | RAS p21 protein activator 3 | 0.0299508 |
| TXNRD1 | thioredoxin reductase 1 | 0.0299218 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0298422 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0295742 |
| PDE1C | phosphodiesterase 1C, calmodulin-dependent 70kDa | 0.0293799 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.028604 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0282591 |
| JUN | jun proto-oncogene | 0.028057 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0277781 |
| ANO6 | anoctamin 6 | 0.0276587 |
| LDHA | lactate dehydrogenase A | 0.0273946 |
| NAV1 | neuron navigator 1 | 0.0268749 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0265521 |
| MCL1 | myeloid cell leukemia 1 | 0.0265396 |
| PLIN2 | perilipin 2 | 0.0264862 |
| RACK1 | receptor for activated C kinase 1 | 0.026314 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0262075 |
| ANXA5 | annexin A5 | 0.0261786 |
| PRKCA | protein kinase C, alpha | 0.0258598 |
| DIAPH2 | diaphanous-related formin 2 | 0.0252378 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0248943 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0248006 |
| FOXP1 | forkhead box P1 | 0.0242526 |
| TNNC1 | troponin C type 1 (slow) | 0.0241684 |
| TPM3 | tropomyosin 3 | 0.0241013 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0239374 |
| YAP1 | Yes-associated protein 1 | 0.0238661 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0234023 |
| RUNX1 | runt-related transcription factor 1 | 0.0232941 |
| ARRDC3 | arrestin domain containing 3 | 0.0232843 |
| TENM3 | teneurin transmembrane protein 3 | 0.0232663 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0232239 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0232197 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0230555 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0227102 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | 0.0226995 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0225914 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0224654 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0224398 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0219793 |
| EZR | ezrin | 0.0219193 |
| MT2A | metallothionein 2A | 0.0218952 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.021758 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0217201 |
| GPC6 | glypican 6 | 0.0217152 |
| PDGFC | platelet derived growth factor C | 0.0216554 |
| CDK6 | cyclin-dependent kinase 6 | 0.0215632 |
| GOLGB1 | golgin B1 | 0.0213081 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | 0.0212118 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0210274 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0210237 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0209862 |
| CALU | calumenin | 0.0207025 |
| NCKAP5 | NCK-associated protein 5 | 0.0206017 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SOD2 | superoxide dismutase 2, mitochondrial | -0.184988 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.129373 |
| HLA-B | major histocompatibility complex, class I, B | -0.124724 |
| TMSB10 | thymosin beta 10 | -0.118669 |
| FNDC3B | fibronectin type III domain containing 3B | -0.10275 |
| FN1 | fibronectin 1 | -0.101818 |
| VIM | vimentin | -0.0927591 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0777723 |
| CADM1 | cell adhesion molecule 1 | -0.0765067 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0727368 |
| RPL23 | ribosomal protein L23 | -0.070653 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0623491 |
| CTSD | cathepsin D | -0.0590808 |
| RPLP2 | ribosomal protein, large, P2 | -0.0582266 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0572387 |
| GNAS | GNAS complex locus | -0.0567307 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0563566 |
| MYOF | myoferlin | -0.05628 |
| IER3 | immediate early response 3 | -0.0558306 |
| RPS6 | ribosomal protein S6 | -0.054461 |
| RBM39 | RNA binding motif protein 39 | -0.0526969 |
| RPS24 | ribosomal protein S24 | -0.0525837 |
| WTAP | Wilms tumor 1 associated protein | -0.052102 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0512454 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.049391 |
| FTL | ferritin, light polypeptide | -0.049199 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0472064 |
| RNF213 | ring finger protein 213 | -0.0463483 |
| FBXO32 | F-box protein 32 | -0.0447204 |
| RIGI | RNA sensor RIG-I | -0.0437282 |
| RPS4X | ribosomal protein S4, X-linked | -0.0436035 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0433691 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0419964 |
| RPL35A | ribosomal protein L35a | -0.0402655 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0402465 |
| PTMA | prothymosin, alpha | -0.0385274 |
| BICC1 | BicC family RNA binding protein 1 | -0.0382315 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0376419 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0374759 |
| RPL5 | ribosomal protein L5 | -0.0361286 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0359999 |
| RPLP1 | ribosomal protein, large, P1 | -0.0359954 |
| SPAG9 | sperm associated antigen 9 | -0.0359221 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0352042 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0342305 |
| RPS12 | ribosomal protein S12 | -0.0340994 |
| WDFY1 | WD repeat and FYVE domain containing 1 | -0.0333696 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0329187 |
| RPS21 | ribosomal protein S21 | -0.0328528 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0322214 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0321186 |
| HLA-A | major histocompatibility complex, class I, A | -0.0316597 |
| RPL19 | ribosomal protein L19 | -0.0313429 |
| HELZ | helicase with zinc finger | -0.0312808 |
| VCAN | versican | -0.0311674 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0307376 |
| NAV2 | neuron navigator 2 | -0.0307099 |
| RPL35 | ribosomal protein L35 | -0.0306682 |
| RPL32 | ribosomal protein L32 | -0.030548 |
| TAPBP | TAP binding protein (tapasin) | -0.0300584 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0294026 |
| SP100 | SP100 nuclear antigen | -0.029102 |
| TUBB | tubulin, beta class I | -0.0290411 |
| OGA | O-GlcNAcase | -0.0289043 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0286945 |
| CD2AP | CD2-associated protein | -0.0286584 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0285633 |
| CENPF | centromere protein F, 350/400kDa | -0.0285149 |
| RPS23 | ribosomal protein S23 | -0.0284236 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0282019 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0281582 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.0281086 |
| COL1A2 | collagen, type I, alpha 2 | -0.0278871 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0275586 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0269242 |
| KYNU | kynureninase | -0.0268763 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0264721 |
| PNPT1 | polyribonucleotide nucleotidyltransferase 1 | -0.0262584 |
| ANKRD12 | ankyrin repeat domain 12 | -0.026186 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0260607 |
| MED13 | mediator complex subunit 13 | -0.0257757 |
| STAG2 | stromal antigen 2 | -0.02563 |
| COL1A1 | collagen, type I, alpha 1 | -0.025617 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0253754 |
| KLHL24 | kelch-like family member 24 | -0.0251353 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0251201 |
| SYAP1 | synapse associated protein 1 | -0.0250873 |
| RPL28 | ribosomal protein L28 | -0.0249139 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0247524 |
| RPL34 | ribosomal protein L34 | -0.0247374 |
| SLC22A4 | solute carrier family 22 (organic cation/zwitterion transporter), member 4 | -0.024463 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0244525 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0242908 |
| RPL31 | ribosomal protein L31 | -0.0239607 |
| ACTG1 | actin gamma 1 | -0.0239451 |
| RPL8 | ribosomal protein L8 | -0.0238267 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0237807 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0237237 |
| RPL9 | ribosomal protein L9 | -0.0236827 |
| FUS | FUS RNA binding protein | -0.023577 |
