| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tofacitinib (citrate) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Tofacitinib (citrate)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.213662 |
| ASPH | aspartate beta-hydroxylase | 0.10164 |
| TMEM156 | transmembrane protein 156 | 0.0895779 |
| FN1 | fibronectin 1 | 0.0820625 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0801064 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0731566 |
| VEGFA | vascular endothelial growth factor A | 0.0725653 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0526749 |
| NRP1 | neuropilin 1 | 0.0491261 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.047687 |
| CD109 | CD109 molecule | 0.0466818 |
| MAP1B | microtubule-associated protein 1B | 0.0458433 |
| FAT1 | FAT atypical cadherin 1 | 0.0457841 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0447381 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0434285 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0419062 |
| TXNIP | thioredoxin interacting protein | 0.0410475 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0410403 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0392692 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0375494 |
| TPR | translocated promoter region, nuclear basket protein | 0.0374588 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.037381 |
| B2M | beta-2-microglobulin | 0.0369645 |
| CD44 | CD44 molecule (Indian blood group) | 0.0361206 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0348145 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0343915 |
| TPM3 | tropomyosin 3 | 0.0342962 |
| CAB39 | calcium binding protein 39 | 0.0342945 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0337594 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0334698 |
| TXNRD1 | thioredoxin reductase 1 | 0.0328355 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0325028 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0318119 |
| MATR3 | matrin 3 | 0.0317991 |
| SMAD3 | SMAD family member 3 | 0.0316893 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0296712 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0294583 |
| PTK2 | protein tyrosine kinase 2 | 0.0290922 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0287888 |
| DST | dystonin | 0.028449 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.027515 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0275036 |
| ARRDC3 | arrestin domain containing 3 | 0.0267227 |
| ETNK1 | ethanolamine kinase 1 | 0.0262875 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0261446 |
| JMJD1C | jumonji domain containing 1C | 0.0256766 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0249593 |
| ENO1 | enolase 1, (alpha) | 0.0248164 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.0248096 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0245461 |
| RTN4 | reticulon 4 | 0.0242306 |
| RNF145 | ring finger protein 145 | 0.0240969 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0239097 |
| FAM13A | family with sequence similarity 13, member A | 0.0238578 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0236116 |
| CALR | calreticulin | 0.0234759 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0232195 |
| NTN4 | netrin 4 | 0.0231494 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0228209 |
| PDS5A | PDS5 cohesin associated factor A | 0.0227079 |
| FNBP1 | formin binding protein 1 | 0.0224815 |
| SVIL | supervillin | 0.0224586 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0223749 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0220196 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0219371 |
| FOSL1 | FOS-like antigen 1 | 0.0218855 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0218792 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0212415 |
| AHR | aryl hydrocarbon receptor | 0.021153 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.021022 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0209977 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0209845 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0207877 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0207468 |
| CDCP1 | CUB domain containing protein 1 | 0.020663 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0206394 |
| COPA | coatomer protein complex, subunit alpha | 0.0205707 |
| MAP3K9 | mitogen-activated protein kinase kinase kinase 9 | 0.020447 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0203996 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0202925 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0201896 |
| PELO | pelota homolog (Drosophila) | 0.0201418 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0200608 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0200464 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0200448 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0199633 |
| RAB22A | RAB22A, member RAS oncogene family | 0.0199185 |
| LAMB1 | laminin, beta 1 | 0.0197762 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0197095 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0196415 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.019608 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.01952 |
| SMYD3 | SET and MYND domain containing 3 | 0.0194868 |
| CREB5 | cAMP responsive element binding protein 5 | 0.0194193 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0193348 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0193223 |
| VEGFC | vascular endothelial growth factor C | 0.0192646 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | 0.0191288 |
| AREG | amphiregulin | 0.0190788 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0189931 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.284426 |
| NRG1 | neuregulin 1 | -0.262573 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.174707 |
| HMGA2 | high mobility group AT-hook 2 | -0.122815 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0940328 |
| TMSB10 | thymosin beta 10 | -0.0882237 |
| INTS6 | integrator complex subunit 6 | -0.0861275 |
| SQSTM1 | sequestosome 1 | -0.0856712 |
| AEBP2 | AE binding protein 2 | -0.0828268 |
| PTMA | prothymosin, alpha | -0.0650495 |
| STC2 | stanniocalcin 2 | -0.0619079 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0562315 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0534967 |
| CANX | calnexin | -0.0529932 |
| PALLD | palladin, cytoskeletal associated protein | -0.0527421 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0522745 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0486773 |
| EFNA5 | ephrin-A5 | -0.0478725 |
| LRRC23 | leucine rich repeat containing 23 | -0.0476303 |
| HLA-B | major histocompatibility complex, class I, B | -0.0460525 |
| PRELID2 | PRELI domain containing 2 | -0.0453338 |
| GNAS | GNAS complex locus | -0.0447903 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0427154 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0411202 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0405586 |
| VCL | vinculin | -0.0401686 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0392194 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0381544 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0381411 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.037967 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0367979 |
| FAM20C | family with sequence similarity 20, member C | -0.0365711 |
| ACTG1 | actin gamma 1 | -0.0361257 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0357413 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.035613 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0352931 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0351301 |
| RPS24 | ribosomal protein S24 | -0.0349656 |
| SYT1 | synaptotagmin I | -0.0349511 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0342408 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0337416 |
| RAI14 | retinoic acid induced 14 | -0.0336452 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0324495 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0319352 |
| AHI1 | Abelson helper integration site 1 | -0.0318139 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0311381 |
| LOX | lysyl oxidase | -0.0310421 |
| TMSB4X | thymosin beta 4, X-linked | -0.0307062 |
| CCDC138 | coiled-coil domain containing 138 | -0.0296986 |
| MT2A | metallothionein 2A | -0.0296 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0292352 |
| FBN1 | fibrillin 1 | -0.0291652 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0289231 |
| CADM1 | cell adhesion molecule 1 | -0.0289071 |
| HDLBP | high density lipoprotein binding protein | -0.028283 |
| RPL35A | ribosomal protein L35a | -0.0281118 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0280735 |
| RPL37A | ribosomal protein L37a | -0.0276587 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0275816 |
| RPL34 | ribosomal protein L34 | -0.0274986 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0271908 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0266889 |
| RPL31 | ribosomal protein L31 | -0.0262699 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0260361 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0260338 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0258484 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0255895 |
| RPL26 | ribosomal protein L26 | -0.0250971 |
| ADIPOR2 | adiponectin receptor 2 | -0.0249159 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0247902 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0244736 |
| ERO1B | endoplasmic reticulum oxidoreductase 1 beta | -0.0243239 |
| POU2F2 | POU class 2 homeobox 2 | -0.0240332 |
| TMEM263 | transmembrane protein 263 | -0.0235387 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0234859 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0232612 |
| IER3 | immediate early response 3 | -0.0231 |
| TUFT1 | tuftelin 1 | -0.0230822 |
| USP34 | ubiquitin specific peptidase 34 | -0.0228544 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.022549 |
| TNS3 | tensin 3 | -0.0222615 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0220097 |
| TENM4 | teneurin transmembrane protein 4 | -0.0216941 |
| LMNA | lamin A/C | -0.0214247 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0213073 |
| RPH3AL | rabphilin 3A-like (without C2 domains) | -0.0210385 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0209726 |
| TGFB1 | transforming growth factor, beta 1 | -0.0209345 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0208891 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0206302 |
| RPL12 | ribosomal protein L12 | -0.0205919 |
| UBAP2 | ubiquitin associated protein 2 | -0.0205188 |
| RTN3 | reticulon 3 | -0.0203422 |
| FUS | FUS RNA binding protein | -0.0200554 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0199554 |
| ABR | active BCR-related | -0.0198227 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0197729 |
| GPC6 | glypican 6 | -0.0196945 |
| KDM4B | lysine (K)-specific demethylase 4B | -0.0196734 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0193585 |
