Toll-like receptor 2-Toll-like receptor 6 protein complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025
Category structural or functional annotations
Type cellular component
Description A heterodimeric protein complex containing Toll-like receptor 2 (TLR2) and Toll-like receptor 6 (TLR6). (Gene Ontology, GO_0035355)
External Link http://amigo.geneontology.org/amigo/term/GO:0035355
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Genes

185 proteins co-occuring with the Toll-like receptor 2-Toll-like receptor 6 protein complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 dataset.

Symbol Name Standardized Value
TLR10 toll-like receptor 10 1.887
KCNS2 potassium voltage-gated channel, modifier subfamily S, member 2 1.785
TLR5 toll-like receptor 5 1.75
TLR2 toll-like receptor 2 1.728
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein 1.715
MYD88 myeloid differentiation primary response 88 1.58
TLR1 toll-like receptor 1 1.517
POLR1E polymerase (RNA) I polypeptide E, 53kDa 1.489
KCNG4 potassium channel, voltage gated modifier subfamily G, member 4 1.467
CRYM crystallin, mu 1.463
KCNH8 potassium channel, voltage gated eag related subfamily H, member 8 1.439
TICAM1 toll-like receptor adaptor molecule 1 1.414
TLR7 toll-like receptor 7 1.366
ALX1 ALX homeobox 1 1.364
TLR9 toll-like receptor 9 1.36
TLR4 toll-like receptor 4 1.359
TLR3 toll-like receptor 3 1.326
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 1.295
ITGAD integrin, alpha D 1.269
TLR6 toll-like receptor 6 1.25
KCNB2 potassium channel, voltage gated Shab related subfamily B, member 2 1.246
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4 1.243
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase 1.205
PIGU phosphatidylinositol glycan anchor biosynthesis, class U 1.194
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 1.188
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 1.185
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 1.176
KCNQ5 potassium channel, voltage gated KQT-like subfamily Q, member 5 1.175
IL31RA interleukin 31 receptor A 1.173
TBXAS1 thromboxane A synthase 1 (platelet) 1.16
CDC73 cell division cycle 73 1.159
FOXH1 forkhead box H1 1.126
SOCS6 suppressor of cytokine signaling 6 1.123
LY96 lymphocyte antigen 96 1.073
SH3RF2 SH3 domain containing ring finger 2 1.071
MAFG v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog G 1.061
IL13 interleukin 13 1.052
CCL4L2 chemokine (C-C motif) ligand 4-like 2 1.05
PEG3 paternally expressed 3 1.043
BEX5 brain expressed, X-linked 5 1.042
PIAS3 protein inhibitor of activated STAT, 3 1.027
IFNLR1 interferon, lambda receptor 1 1.026
NLRP13 NLR family, pyrin domain containing 13 1.024
IL27RA interleukin 27 receptor, alpha 1.02
SUCLG1 succinate-CoA ligase, alpha subunit 1.019
DDX56 DEAD (Asp-Glu-Ala-Asp) box helicase 56 1.018
PTGIS prostaglandin I2 (prostacyclin) synthase 1.015
TOM1 target of myb1 (chicken) 1.014
IL4 interleukin 4 1.003
DSCAM Down syndrome cell adhesion molecule 1.003
NPAS2 neuronal PAS domain protein 2 1.0
EPHA3 EPH receptor A3 0.977
IL10 interleukin 10 0.965
PYCARD PYD and CARD domain containing 0.964
GRPEL2 GrpE-like 2, mitochondrial (E. coli) 0.955
PTGDS prostaglandin D2 synthase 21kDa (brain) 0.951
UNC93B1 unc-93 homolog B1 (C. elegans) 0.947
IL21R interleukin 21 receptor 0.944
IL1B interleukin 1, beta 0.941
NLRP8 NLR family, pyrin domain containing 8 0.941
ACKR3 atypical chemokine receptor 3 0.929
FSTL1 follistatin-like 1 0.925
LTB lymphotoxin beta (TNF superfamily, member 3) 0.914
IRAK2 interleukin-1 receptor-associated kinase 2 0.914
JAK1 Janus kinase 1 0.913
IL10RB interleukin 10 receptor, beta 0.911
ARHGAP35 Rho GTPase activating protein 35 0.906
SVOP SV2 related protein homolog (rat) 0.883
IL1R2 interleukin 1 receptor, type II 0.883
NLRP11 NLR family, pyrin domain containing 11 0.882
LGMN legumain 0.882
IRF2 interferon regulatory factor 2 0.874
FNDC3A fibronectin type III domain containing 3A 0.869
BAHD1 bromo adjacent homology domain containing 1 0.867
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) 0.864
ZIM3 zinc finger, imprinted 3 0.862
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.861
CXCL10 chemokine (C-X-C motif) ligand 10 0.859
IL1A interleukin 1, alpha 0.858
TRAF3IP3 TRAF3 interacting protein 3 0.854
TMTC2 transmembrane and tetratricopeptide repeat containing 2 0.846
WNT2 wingless-type MMTV integration site family member 2 0.845
IFNB1 interferon, beta 1, fibroblast 0.841
PNRC2 proline-rich nuclear receptor coactivator 2 0.839
TLR8 toll-like receptor 8 0.836
IL2RB interleukin 2 receptor, beta 0.833
KCNB1 potassium channel, voltage gated Shab related subfamily B, member 1 0.831
CIMAP3 ciliary microtubule associated protein 3 0.824
THSD4 thrombospondin, type I, domain containing 4 0.82
TNFRSF14 tumor necrosis factor receptor superfamily, member 14 0.82
IL10RA interleukin 10 receptor, alpha 0.809
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.809
MGST2 microsomal glutathione S-transferase 2 0.806
PTGES prostaglandin E synthase 0.803
NLRP14 NLR family, pyrin domain containing 14 0.786
CASP4 caspase 4, apoptosis-related cysteine peptidase 0.78
BAG3 BCL2-associated athanogene 3 0.778
NTN1 netrin 1 0.775
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 0.774
NCOA3 nuclear receptor coactivator 3 0.772
FGFR4 fibroblast growth factor receptor 4 0.767
SIGLEC14 sialic acid binding Ig-like lectin 14 0.766
GBP7 guanylate binding protein 7 0.765
NLRP9 NLR family, pyrin domain containing 9 0.754
RNF138 ring finger protein 138, E3 ubiquitin protein ligase 0.753
CDH18 cadherin 18, type 2 0.751
CLOCK clock circadian regulator 0.75
TPTEP2-CSNK1E TPTEP2-CSNK1E readthrough 0.747
CCR3 chemokine (C-C motif) receptor 3 0.745
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.741
IL6R interleukin 6 receptor 0.737
EPHA1 EPH receptor A1 0.737
IL2RG interleukin 2 receptor, gamma 0.736
GBP2 guanylate binding protein 2, interferon-inducible 0.73
CXCL9 chemokine (C-X-C motif) ligand 9 0.722
CMYA5 cardiomyopathy associated 5 0.722
CASP1 caspase 1, apoptosis-related cysteine peptidase 0.722
CCL2 chemokine (C-C motif) ligand 2 0.717
CXCL6 chemokine (C-X-C motif) ligand 6 0.707
HLA-DQA2 major histocompatibility complex, class II, DQ alpha 2 0.701
C8G complement component 8, gamma polypeptide 0.701
EFNA5 ephrin-A5 0.695
CDC6 cell division cycle 6 0.691
CCR1 chemokine (C-C motif) receptor 1 0.688
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.687
FADD Fas (TNFRSF6)-associated via death domain 0.674
TRADD TNFRSF1A-associated via death domain 0.665
NOD2 nucleotide-binding oligomerization domain containing 2 0.658
NLRP5 NLR family, pyrin domain containing 5 0.652
CCL19 chemokine (C-C motif) ligand 19 0.651
ATL1 atlastin GTPase 1 0.65
IRF1 interferon regulatory factor 1 0.647
LTA lymphotoxin alpha 0.646
IFNA13 interferon, alpha 13 0.646
IRAK1 interleukin-1 receptor-associated kinase 1 0.637
SORCS2 sortilin-related VPS10 domain containing receptor 2 0.632
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal) 0.632
BIRC2 baculoviral IAP repeat containing 2 0.63
ELOVL7 ELOVL fatty acid elongase 7 0.626
JAK3 Janus kinase 3 0.626
NOD1 nucleotide-binding oligomerization domain containing 1 0.625
FGFR3 fibroblast growth factor receptor 3 0.624
IL12RB2 interleukin 12 receptor, beta 2 0.618
IRF7 interferon regulatory factor 7 0.616
IL1R1 interleukin 1 receptor, type I 0.612
BMAL1 basic helix-loop-helix ARNT like 1 0.607
IL6 interleukin 6 0.605
IL18 interleukin 18 0.6
RNF125 ring finger protein 125, E3 ubiquitin protein ligase 0.595
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.592
FBL fibrillarin 0.592
SLC30A7 solute carrier family 30 (zinc transporter), member 7 0.587
RIPK2 receptor-interacting serine-threonine kinase 2 0.574
IL2RA interleukin 2 receptor, alpha 0.573
FGFR2 fibroblast growth factor receptor 2 0.571
CTSK cathepsin K 0.57
NELL1 NEL-like 1 (chicken) 0.569
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 0.569
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 0.568
DEDD death effector domain containing 0.561
MED23 mediator complex subunit 23 0.561
CD163 CD163 molecule 0.561
IL3 interleukin 3 0.558
CXCL11 chemokine (C-X-C motif) ligand 11 0.555
CHAMP1 chromosome alignment maintaining phosphoprotein 1 0.551
AKTIP AKT interacting protein 0.551
NLRP4 NLR family, pyrin domain containing 4 0.545
LACC1 laccase (multicopper oxidoreductase) domain containing 1 0.545
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.543
CIITA class II, major histocompatibility complex, transactivator 0.542
PCDHB11 protocadherin beta 11 0.535
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.534
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 0.532
CD180 CD180 molecule 0.53
KIF13B kinesin family member 13B 0.53
CARD14 caspase recruitment domain family, member 14 0.526
CPOX coproporphyrinogen oxidase 0.526
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa 0.525
TG thyroglobulin 0.521
CREBBP CREB binding protein 0.515
H1-6 H1.6 linker histone, cluster member 0.515
CD40LG CD40 ligand 0.514
JAZF1 JAZF zinc finger 1 0.509
CCL3L1 chemokine (C-C motif) ligand 3-like 1 0.501
PARP9 poly (ADP-ribose) polymerase family, member 9 0.5