| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tolmetin perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tolmetin_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.119693 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.109198 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.100968 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0756984 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0668435 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0668052 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0663358 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0625554 |
| DSPP | dentin sialophosphoprotein | 0.0604499 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0569467 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.049799 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0458557 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0454407 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0433247 |
| GOLGA4 | golgin A4 | 0.0430531 |
| PRELID2 | PRELI domain containing 2 | 0.0420763 |
| HYOU1 | hypoxia up-regulated 1 | 0.0411416 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0394166 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.038865 |
| PTEN | phosphatase and tensin homolog | 0.0388543 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.03871 |
| CALR | calreticulin | 0.0382561 |
| ENO1 | enolase 1, (alpha) | 0.0372347 |
| FAT1 | FAT atypical cadherin 1 | 0.0367437 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0358759 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0349308 |
| PGK1 | phosphoglycerate kinase 1 | 0.0347987 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0344393 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0343472 |
| DYNC2I1 | dynein 2 intermediate chain 1 | 0.0342438 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0340047 |
| CANX | calnexin | 0.0335581 |
| HELZ | helicase with zinc finger | 0.0332257 |
| TPM3 | tropomyosin 3 | 0.0325551 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0324366 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0320723 |
| RNF149 | ring finger protein 149 | 0.0320163 |
| COG6 | component of oligomeric golgi complex 6 | 0.0319386 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0317616 |
| GOLGB1 | golgin B1 | 0.0310878 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0304268 |
| STYXL2 | serine/threonine/tyrosine interacting like 2 | 0.0302887 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0296369 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0295294 |
| ABHD2 | abhydrolase domain containing 2 | 0.0294957 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0286048 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0284066 |
| VEGFA | vascular endothelial growth factor A | 0.0283519 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0281798 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.028146 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0278555 |
| PKM | pyruvate kinase, muscle | 0.0275746 |
| APOL1 | apolipoprotein L, 1 | 0.027484 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.027146 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0270642 |
| ARRDC3 | arrestin domain containing 3 | 0.0270053 |
| NDRG1 | N-myc downstream regulated 1 | 0.0266112 |
| PCBP2 | poly(rC) binding protein 2 | 0.0265715 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.026522 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0263182 |
| RPL3 | ribosomal protein L3 | 0.0262048 |
| EHF | ets homologous factor | 0.0256144 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0252574 |
| USPL1 | ubiquitin specific peptidase like 1 | 0.0251116 |
| TMF1 | TATA element modulatory factor 1 | 0.0250079 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0249092 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0247615 |
| TPI1 | triosephosphate isomerase 1 | 0.0246755 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0244243 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.024178 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0239018 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0238509 |
| ERCC5 | excision repair cross-complementation group 5 | 0.0237229 |
| LYZ | lysozyme | 0.0235427 |
| KIF16B | kinesin family member 16B | 0.0232887 |
| PNN | pinin, desmosome associated protein | 0.0230023 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0229467 |
| XPO1 | exportin 1 | 0.0228966 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0227616 |
| FOSL2 | FOS-like antigen 2 | 0.0227349 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | 0.0225532 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | 0.02255 |
| TFG | TRK-fused gene | 0.0222342 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0221945 |
| NBAS | neuroblastoma amplified sequence | 0.0221249 |
| FAM13A | family with sequence similarity 13, member A | 0.0219601 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0217875 |
| CALU | calumenin | 0.0217738 |
| GOLGA2 | golgin A2 | 0.0217451 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0216777 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0213259 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0211452 |
| MLEC | malectin | 0.0210198 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0209096 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0208738 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0208662 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0208398 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0207842 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0207782 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | 0.020769 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.137892 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.134457 |
| LCN2 | lipocalin 2 | -0.126987 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.12581 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.116598 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.115061 |
| HLA-B | major histocompatibility complex, class I, B | -0.114808 |
| MYO1E | myosin IE | -0.101155 |
| LMO7 | LIM domain 7 | -0.0994087 |
| RNF213 | ring finger protein 213 | -0.0961197 |
| SP100 | SP100 nuclear antigen | -0.0949746 |
| RIGI | RNA sensor RIG-I | -0.0947336 |
| PLSCR1 | phospholipid scramblase 1 | -0.0929099 |
| MX2 | MX dynamin-like GTPase 2 | -0.0890809 |
| PERP | PERP, TP53 apoptosis effector | -0.0873728 |
| ANXA2 | annexin A2 | -0.0837516 |
| TMC5 | transmembrane channel-like 5 | -0.0826804 |
| XAF1 | XIAP associated factor 1 | -0.0793499 |
| VCL | vinculin | -0.077969 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0728649 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0688738 |
| EGR1 | early growth response 1 | -0.0648408 |
| HLA-C | major histocompatibility complex, class I, C | -0.0637261 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0622686 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0620094 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.06123 |
| NCKAP5 | NCK-associated protein 5 | -0.0603613 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0595653 |
| MX1 | MX dynamin-like GTPase 1 | -0.058975 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0572088 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0556902 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.055675 |
| HLA-E | major histocompatibility complex, class I, E | -0.0537656 |
| TJP1 | tight junction protein 1 | -0.0537176 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0536011 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.052859 |
| INTS6 | integrator complex subunit 6 | -0.052792 |
| MAP7 | microtubule-associated protein 7 | -0.0526453 |
| SPATA13 | spermatogenesis associated 13 | -0.0524251 |
| SERINC5 | serine incorporator 5 | -0.048415 |
| ATP11A | ATPase, class VI, type 11A | -0.0480468 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0477521 |
| PMP22 | peripheral myelin protein 22 | -0.047032 |
| ACTN4 | actinin, alpha 4 | -0.046484 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0461686 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0455719 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0439812 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0433763 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0431373 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0428656 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | -0.0428208 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0418759 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0408574 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0407676 |
| ERBIN | erbb2 interacting protein | -0.0405296 |
| EPHB2 | EPH receptor B2 | -0.0401907 |
| TMEM62 | transmembrane protein 62 | -0.0401233 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0400632 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0397482 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0395274 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0394979 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0391755 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0391135 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0388602 |
| PATJ | PATJ crumbs cell polarity complex component | -0.038822 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0384094 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | -0.0383251 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.038083 |
| ETV6 | ets variant 6 | -0.0376731 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0374689 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0372965 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0370821 |
| SMAD3 | SMAD family member 3 | -0.036472 |
| S100A10 | S100 calcium binding protein A10 | -0.0363953 |
| KIAA1217 | KIAA1217 | -0.0360129 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | -0.0359763 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0359671 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0358169 |
| KLF6 | Kruppel-like factor 6 | -0.0356677 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0356466 |
| FOXP1 | forkhead box P1 | -0.0352273 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0347169 |
| FOXO3 | forkhead box O3 | -0.0340238 |
| FHL2 | four and a half LIM domains 2 | -0.0340034 |
| RPS24 | ribosomal protein S24 | -0.0338579 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0335863 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0334623 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0331721 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.033003 |
| SQSTM1 | sequestosome 1 | -0.0327581 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.032709 |
| VMP1 | vacuole membrane protein 1 | -0.0323055 |
| TOX3 | TOX high mobility group box family member 3 | -0.0311652 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0306808 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0305976 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0304334 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0298688 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0296488 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0294512 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0293691 |
