| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tolmetin perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tolmetin_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.107277 |
| MEF2A | myocyte enhancer factor 2A | 0.0963864 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0939131 |
| CLU | clusterin | 0.0923816 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0916065 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0882242 |
| PLEC | plectin | 0.086461 |
| PGK1 | phosphoglycerate kinase 1 | 0.0836311 |
| MYOF | myoferlin | 0.071664 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0699061 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.066324 |
| ENO1 | enolase 1, (alpha) | 0.0652562 |
| KRT17 | keratin 17, type I | 0.0641559 |
| OGA | O-GlcNAcase | 0.0636177 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0622658 |
| ANLN | anillin, actin binding protein | 0.0618481 |
| CUL4B | cullin 4B | 0.0613124 |
| EMP1 | epithelial membrane protein 1 | 0.0574793 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.05449 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0541317 |
| ITGA6 | integrin, alpha 6 | 0.0538905 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0535175 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0534787 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0532224 |
| FN1 | fibronectin 1 | 0.0528753 |
| NRG1 | neuregulin 1 | 0.052011 |
| BCL2L1 | BCL2-like 1 | 0.0500424 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0500191 |
| KIAA1217 | KIAA1217 | 0.0496865 |
| ARRDC3 | arrestin domain containing 3 | 0.0485507 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0464638 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0462593 |
| AHNAK | AHNAK nucleoprotein | 0.0454738 |
| TMSB4X | thymosin beta 4, X-linked | 0.0448305 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0445698 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0436278 |
| GOLGA4 | golgin A4 | 0.0433626 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0432672 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0429289 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0428729 |
| MYO10 | myosin X | 0.0419687 |
| H1-0 | H1.0 linker histone | 0.0402804 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0401056 |
| UBE2V1 | ubiquitin-conjugating enzyme E2 variant 1 | 0.0397106 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.038843 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0386176 |
| KRT6A | keratin 6A, type II | 0.0385606 |
| ZNF292 | zinc finger protein 292 | 0.0382013 |
| PLAT | plasminogen activator, tissue | 0.0381102 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0376097 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0373385 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0368212 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0366423 |
| FOXP1 | forkhead box P1 | 0.0361277 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0355091 |
| EHF | ets homologous factor | 0.0350787 |
| MSN | moesin | 0.0343199 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0342828 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.034158 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0337292 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0332513 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | 0.0330343 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.032766 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0323129 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0321502 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0320878 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0320052 |
| NEK7 | NIMA-related kinase 7 | 0.0312614 |
| EZR | ezrin | 0.031255 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0310754 |
| KDM7A | lysine (K)-specific demethylase 7A | 0.0310136 |
| RNF145 | ring finger protein 145 | 0.0309536 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0309117 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0307902 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0306349 |
| LMNA | lamin A/C | 0.0305827 |
| RPL3 | ribosomal protein L3 | 0.0304683 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | 0.0302357 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0302122 |
| TPM3 | tropomyosin 3 | 0.029996 |
| KRT14 | keratin 14, type I | 0.0299182 |
| AFAP1 | actin filament associated protein 1 | 0.0298959 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0298787 |
| CALR | calreticulin | 0.0297773 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0297658 |
| NUP58 | nucleoporin 58 | 0.0297249 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0296584 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0294463 |
| EFHD2 | EF-hand domain family, member D2 | 0.0293761 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0290397 |
| LOXL2 | lysyl oxidase-like 2 | 0.0290306 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.02877 |
| PHF21A | PHD finger protein 21A | 0.0285285 |
| SERINC3 | serine incorporator 3 | 0.0284353 |
| GATA6 | GATA binding protein 6 | 0.0274738 |
| SULF1 | sulfatase 1 | 0.0272986 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0271486 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0271387 |
| APP | amyloid beta (A4) precursor protein | 0.0269877 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.0269368 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.209072 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.20813 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.127403 |
| PDLIM5 | PDZ and LIM domain 5 | -0.112502 |
| INTS6 | integrator complex subunit 6 | -0.110665 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.109606 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.102738 |
| MTSS1 | metastasis suppressor 1 | -0.102508 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.101565 |
| LMO7 | LIM domain 7 | -0.0923913 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0851946 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0754947 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0742234 |
| HMGA2 | high mobility group AT-hook 2 | -0.0683622 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0649813 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0622911 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0595143 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0589148 |
| RASAL2 | RAS protein activator like 2 | -0.0572496 |
| SULF2 | sulfatase 2 | -0.0562719 |
| LAMA5 | laminin, alpha 5 | -0.0542872 |
| PLS3 | plastin 3 | -0.0516668 |
| EXT1 | exostosin glycosyltransferase 1 | -0.051292 |
| EFNA5 | ephrin-A5 | -0.0478237 |
| RIGI | RNA sensor RIG-I | -0.046838 |
| RCOR1 | REST corepressor 1 | -0.0459511 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0443751 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0441141 |
| LAMC2 | laminin, gamma 2 | -0.0431851 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0428873 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0423109 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0422207 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0421415 |
| PALLD | palladin, cytoskeletal associated protein | -0.0412597 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.040986 |
| HDAC9 | histone deacetylase 9 | -0.0404328 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0377099 |
| DGKH | diacylglycerol kinase, eta | -0.0373656 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0368928 |
| RNF217 | ring finger protein 217 | -0.0362021 |
| SETX | senataxin | -0.0357131 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0353243 |
| EGFR | epidermal growth factor receptor | -0.0351079 |
| RAI14 | retinoic acid induced 14 | -0.0346081 |
| CDK6 | cyclin-dependent kinase 6 | -0.0343452 |
| TNS3 | tensin 3 | -0.0337813 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0335545 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0328245 |
| IFI44L | interferon-induced protein 44-like | -0.0328233 |
| HLA-B | major histocompatibility complex, class I, B | -0.0323437 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0313289 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0308886 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0303104 |
| PRSS23 | protease, serine, 23 | -0.0303103 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0301862 |
| CNTNAP3 | contactin associated protein-like 3 | -0.0301718 |
| CSMD2 | CUB and Sushi multiple domains 2 | -0.0300943 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0298224 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0295366 |
| CUX1 | cut-like homeobox 1 | -0.0294442 |
| EXOC4 | exocyst complex component 4 | -0.0293714 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.029328 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0292565 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0292148 |
| PODXL | podocalyxin-like | -0.0291684 |
| MECOM | MDS1 and EVI1 complex locus | -0.0285679 |
| KLF12 | Kruppel-like factor 12 | -0.0279128 |
| MEGF6 | multiple EGF-like-domains 6 | -0.0277043 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0275318 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0270484 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0268677 |
| EGR1 | early growth response 1 | -0.0268461 |
| RAD51B | RAD51 paralog B | -0.0264452 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0261981 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0260476 |
| CTBP2 | C-terminal binding protein 2 | -0.0259435 |
| LUZP1 | leucine zipper protein 1 | -0.025724 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0256344 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0253512 |
| FRMD6 | FERM domain containing 6 | -0.0249335 |
| SYN3 | synapsin III | -0.0249087 |
| NCKAP5 | NCK-associated protein 5 | -0.0248268 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0246575 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0244807 |
| HM13 | histocompatibility (minor) 13 | -0.0243699 |
| UTRN | utrophin | -0.0243324 |
| DHFR | dihydrofolate reductase | -0.0242856 |
| ABCA13 | ATP-binding cassette, sub-family A (ABC1), member 13 | -0.0239356 |
| DENND1A | DENN/MADD domain containing 1A | -0.02388 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0236956 |
| RHOJ | ras homolog family member J | -0.0232984 |
| RPS8 | ribosomal protein S8 | -0.0232706 |
| CORO2A | coronin, actin binding protein, 2A | -0.0230414 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0228747 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0228675 |
| HMGA1 | high mobility group AT-hook 1 | -0.022857 |
| SIK3 | SIK family kinase 3 | -0.0228308 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0228079 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0227892 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0225108 |
