| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tolmetin perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tolmetin_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | 0.214793 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.128725 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.107513 |
| HYOU1 | hypoxia up-regulated 1 | 0.0946259 |
| KLHL29 | kelch-like family member 29 | 0.0751785 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0713405 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0712374 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0697486 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0653557 |
| ATXN1 | ataxin 1 | 0.0626968 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0578788 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0565418 |
| CADPS2 | Ca++-dependent secretion activator 2 | 0.0540811 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0511729 |
| GOLGA4 | golgin A4 | 0.0511519 |
| DSPP | dentin sialophosphoprotein | 0.0495266 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0486807 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0480684 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0467224 |
| GOLGB1 | golgin B1 | 0.0452242 |
| TES | testin LIM domain protein | 0.0441731 |
| PLEC | plectin | 0.0424183 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0419434 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0416656 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0414379 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0411293 |
| AREG | amphiregulin | 0.0408784 |
| CDK13 | cyclin-dependent kinase 13 | 0.0405492 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0401192 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0399603 |
| LMO7 | LIM domain 7 | 0.0381251 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0378087 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0371295 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0365489 |
| RBM39 | RNA binding motif protein 39 | 0.0363105 |
| SETD5 | SET domain containing 5 | 0.0359536 |
| RUNX1 | runt-related transcription factor 1 | 0.0352899 |
| CCNY | cyclin Y | 0.0349835 |
| COG5 | component of oligomeric golgi complex 5 | 0.0347593 |
| SIK3 | SIK family kinase 3 | 0.0341914 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0336261 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0334913 |
| SRPRA | SRP receptor subunit alpha | 0.0330861 |
| FNIP1 | folliculin interacting protein 1 | 0.0327277 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0323903 |
| CANX | calnexin | 0.0320424 |
| MYO5B | myosin VB | 0.0316788 |
| LAMB3 | laminin, beta 3 | 0.0315124 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0311175 |
| HKDC1 | hexokinase domain containing 1 | 0.0310919 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0310492 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0309539 |
| PMM2 | phosphomannomutase 2 | 0.0306618 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.030496 |
| IARS1 | isoleucyl-tRNA synthetase 1 | 0.0302162 |
| FRMD5 | FERM domain containing 5 | 0.03013 |
| TMSB4X | thymosin beta 4, X-linked | 0.0296395 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0296251 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | 0.0295342 |
| ERP44 | endoplasmic reticulum protein 44 | 0.0292518 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0292261 |
| GOLGA3 | golgin A3 | 0.0289083 |
| PIP5K1B | phosphatidylinositol-4-phosphate 5-kinase, type I, beta | 0.0287211 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0287151 |
| AHNAK | AHNAK nucleoprotein | 0.0286058 |
| RPL4 | ribosomal protein L4 | 0.0282968 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0282786 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0281842 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0280592 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0280243 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0277757 |
| PTMA | prothymosin, alpha | 0.0277247 |
| XPOT | exportin, tRNA | 0.0277087 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.027602 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0275974 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0274426 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0272759 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0271799 |
| RPS2 | ribosomal protein S2 | 0.027091 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0270656 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0270624 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0269448 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0267507 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | 0.0262932 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.026212 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0260078 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0259501 |
| KIF16B | kinesin family member 16B | 0.0258174 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0256413 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0254289 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0252703 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.025156 |
| RPL3 | ribosomal protein L3 | 0.0250196 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0249596 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0248634 |
| PREPL | prolyl endopeptidase-like | 0.0247797 |
| APP | amyloid beta (A4) precursor protein | 0.0246471 |
| RPL37A | ribosomal protein L37a | 0.0246201 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0246197 |
| COG6 | component of oligomeric golgi complex 6 | 0.0244386 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.222914 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.179074 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.151191 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.104403 |
| TMSB10 | thymosin beta 10 | -0.0836033 |
| B2M | beta-2-microglobulin | -0.083523 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0810975 |
| S100A10 | S100 calcium binding protein A10 | -0.0723592 |
| ANXA2 | annexin A2 | -0.0714113 |
| CLDN4 | claudin 4 | -0.0710611 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0698858 |
| POTEF | POTE ankyrin domain family, member F | -0.0667975 |
| S100A6 | S100 calcium binding protein A6 | -0.0656685 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0639528 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0572262 |
| TMC5 | transmembrane channel-like 5 | -0.0571235 |
| FTL | ferritin, light polypeptide | -0.0568447 |
| KRT19 | keratin 19, type I | -0.0555501 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0552923 |
| GSTP1 | glutathione S-transferase pi 1 | -0.0552802 |
| EMP1 | epithelial membrane protein 1 | -0.0543742 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0542119 |
| GPX2 | glutathione peroxidase 2 | -0.0539035 |
| CLDN7 | claudin 7 | -0.0535134 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0534355 |
| MUC1 | mucin 1, cell surface associated | -0.05181 |
| LYZ | lysozyme | -0.0511416 |
| AGR3 | anterior gradient 3 | -0.0500754 |
| EPCAM | epithelial cell adhesion molecule | -0.0499345 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0497085 |
| HLA-A | major histocompatibility complex, class I, A | -0.0487317 |
| EZR | ezrin | -0.0470357 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0432019 |
| ACTN4 | actinin, alpha 4 | -0.0423737 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0422927 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0405414 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0404765 |
| INSIG1 | insulin induced gene 1 | -0.0403097 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | -0.0401643 |
| TMEM123 | transmembrane protein 123 | -0.0397615 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0397589 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0395515 |
| LIMA1 | LIM domain and actin binding 1 | -0.0377185 |
| MKI67 | marker of proliferation Ki-67 | -0.0374989 |
| NDUFA4 | NDUFA4, mitochondrial complex associated | -0.0372868 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0371003 |
| PERP | PERP, TP53 apoptosis effector | -0.0368473 |
| TUBA1B | tubulin, alpha 1b | -0.0368124 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0365231 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0354504 |
| ANLN | anillin, actin binding protein | -0.0351289 |
| S100A9 | S100 calcium binding protein A9 | -0.0346568 |
| H3-3B | H3.3 histone B | -0.0344897 |
| ITGB4 | integrin, beta 4 | -0.034071 |
| CBX3 | chromobox homolog 3 | -0.0337616 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0335847 |
| S100A11 | S100 calcium binding protein A11 | -0.0335668 |
| CST3 | cystatin C | -0.0333946 |
| TMEM45B | transmembrane protein 45B | -0.0327825 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0327484 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0326182 |
| RPLP1 | ribosomal protein, large, P1 | -0.0325914 |
| PFN1 | profilin 1 | -0.0318247 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0316669 |
| S100P | S100 calcium binding protein P | -0.0315599 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0312482 |
| RPL28 | ribosomal protein L28 | -0.0311783 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0309835 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | -0.030679 |
| DEK | DEK proto-oncogene | -0.0302532 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0299959 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0296816 |
| RPS19 | ribosomal protein S19 | -0.029112 |
| BSG | basigin (Ok blood group) | -0.0290191 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.0286773 |
| RPL35A | ribosomal protein L35a | -0.0285676 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0284135 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0283533 |
| RPL19 | ribosomal protein L19 | -0.0283053 |
| GNB2 | guanine nucleotide binding protein (G protein), beta polypeptide 2 | -0.0280481 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0269416 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0267133 |
| LIPH | lipase, member H | -0.0267102 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0263484 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0262093 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0262024 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0259793 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.0259685 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0259121 |
| MUC3B | mucin 3B, cell surface associated | -0.0255605 |
| JUP | junction plakoglobin | -0.0255023 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0254059 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0253743 |
| CDCP1 | CUB domain containing protein 1 | -0.0253115 |
| KLK10 | kallikrein-related peptidase 10 | -0.0252058 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0250029 |
| RNF213 | ring finger protein 213 | -0.0248454 |
| LMNA | lamin A/C | -0.0248071 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0246563 |
| ECT2 | epithelial cell transforming 2 | -0.0244939 |
