| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tolmetin perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tolmetin_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.097271 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0910045 |
| RPL3 | ribosomal protein L3 | 0.0866304 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0858165 |
| TMSB10 | thymosin beta 10 | 0.0824093 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0775957 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0675504 |
| TMSB4X | thymosin beta 4, X-linked | 0.0674711 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0671617 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0647983 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0605315 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0588754 |
| RNF145 | ring finger protein 145 | 0.0549529 |
| RPS12 | ribosomal protein S12 | 0.0542385 |
| RPS2 | ribosomal protein S2 | 0.0536311 |
| KRT8 | keratin 8, type II | 0.0508463 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0504785 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0498539 |
| EREG | epiregulin | 0.0488916 |
| GRB10 | growth factor receptor-bound protein 10 | 0.048217 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0479477 |
| RPL13A | ribosomal protein L13a | 0.0477409 |
| RPS19 | ribosomal protein S19 | 0.0460671 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0424852 |
| KRT18 | keratin 18, type I | 0.0404612 |
| RPL26 | ribosomal protein L26 | 0.0403059 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0388317 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0387948 |
| RPS3 | ribosomal protein S3 | 0.0376555 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0374804 |
| RBM39 | RNA binding motif protein 39 | 0.0362497 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0345878 |
| FAM13A | family with sequence similarity 13, member A | 0.0339671 |
| XPO1 | exportin 1 | 0.033294 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.033152 |
| RPL23 | ribosomal protein L23 | 0.0330261 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0329792 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0324775 |
| MYO5B | myosin VB | 0.0320605 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0316307 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0314163 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0313079 |
| RPL37A | ribosomal protein L37a | 0.0312388 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0310379 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0308818 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0307111 |
| YME1L1 | YME1-like 1 ATPase | 0.0302518 |
| NUP58 | nucleoporin 58 | 0.0300384 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0294971 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.0291671 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0290576 |
| RPS15A | ribosomal protein S15a | 0.0288761 |
| RPL35A | ribosomal protein L35a | 0.0288606 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0287191 |
| HYOU1 | hypoxia up-regulated 1 | 0.0284726 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0281646 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.027752 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0270189 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0269895 |
| S100P | S100 calcium binding protein P | 0.0263519 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.0263485 |
| RPL35 | ribosomal protein L35 | 0.0262646 |
| LCORL | ligand dependent nuclear receptor corepressor-like | 0.0261738 |
| RPL4 | ribosomal protein L4 | 0.026068 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0257758 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0257593 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0255565 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | 0.0252993 |
| B2M | beta-2-microglobulin | 0.0252667 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0247991 |
| H2AC6 | H2A clustered histone 6 | 0.0247482 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0246666 |
| RPL34 | ribosomal protein L34 | 0.0245893 |
| PNN | pinin, desmosome associated protein | 0.0244973 |
| SET | SET nuclear proto-oncogene | 0.0243185 |
| CALR | calreticulin | 0.0241579 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.024151 |
| XPOT | exportin, tRNA | 0.024092 |
| CCNY | cyclin Y | 0.0240564 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0239779 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0238668 |
| YTHDC1 | YTH domain containing 1 | 0.0238227 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0237733 |
| RPSA | ribosomal protein SA | 0.0237587 |
| COG5 | component of oligomeric golgi complex 5 | 0.0231907 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0230533 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0230459 |
| RPL36 | ribosomal protein L36 | 0.0230223 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0229376 |
| H1-4 | H1.4 linker histone, cluster member | 0.0229309 |
| DHX9 | DEAH (Asp-Glu-Ala-His) box helicase 9 | 0.0229118 |
| MED13L | mediator complex subunit 13-like | 0.0229072 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0228121 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0227631 |
| LAMB3 | laminin, beta 3 | 0.0226553 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0226551 |
| TFG | TRK-fused gene | 0.0224236 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0222984 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0219145 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0217494 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.385662 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.173554 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.124948 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.11529 |
| ANXA2 | annexin A2 | -0.081859 |
| MYO1E | myosin IE | -0.0806842 |
| TRIM2 | tripartite motif containing 2 | -0.0788912 |
| NDRG1 | N-myc downstream regulated 1 | -0.0781419 |
| LDHA | lactate dehydrogenase A | -0.0775487 |
| ANTXR2 | anthrax toxin receptor 2 | -0.076568 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0708165 |
| FAT1 | FAT atypical cadherin 1 | -0.0667626 |
| EZR | ezrin | -0.0567715 |
| CADPS | Ca++-dependent secretion activator | -0.0565075 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.052638 |
| PTEN | phosphatase and tensin homolog | -0.0520491 |
| LMO7 | LIM domain 7 | -0.0515228 |
| TXNIP | thioredoxin interacting protein | -0.050085 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0492187 |
| ATXN1 | ataxin 1 | -0.0489741 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.048035 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0474975 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0470405 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.046936 |
| TNS4 | tensin 4 | -0.0459845 |
| ITGA6 | integrin, alpha 6 | -0.0456518 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0437142 |
| PERP | PERP, TP53 apoptosis effector | -0.0431199 |
| FHIT | fragile histidine triad | -0.0410586 |
| RNF43 | ring finger protein 43 | -0.0406572 |
| NPSR1 | neuropeptide S receptor 1 | -0.0402684 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0385546 |
| DSG2 | desmoglein 2 | -0.0381694 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0372561 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0369364 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0368263 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0365079 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0360074 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.035497 |
| CD44 | CD44 molecule (Indian blood group) | -0.0353407 |
| SBF2 | SET binding factor 2 | -0.0352039 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.03464 |
| POTEF | POTE ankyrin domain family, member F | -0.0346242 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0334535 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.033367 |
| TPM4 | tropomyosin 4 | -0.0329405 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0329122 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0327098 |
| MUC13 | mucin 13, cell surface associated | -0.032419 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0320498 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0318025 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.0317228 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0316073 |
| MYO1D | myosin ID | -0.0313588 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0313478 |
| MED13 | mediator complex subunit 13 | -0.031065 |
| SH3D19 | SH3 domain containing 19 | -0.0309473 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0309275 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0307116 |
| GOLGB1 | golgin B1 | -0.0301423 |
| KAZN | kazrin, periplakin interacting protein | -0.0301136 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0301077 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0300741 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0299472 |
| CALB1 | calbindin 1, 28kDa | -0.0297403 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0296064 |
| KIAA1217 | KIAA1217 | -0.0294843 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.029419 |
| CCNI | cyclin I | -0.0292104 |
| TMEM45B | transmembrane protein 45B | -0.0289609 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0289517 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | -0.0288698 |
| CMIP | c-Maf inducing protein | -0.028549 |
| SPON1 | spondin 1, extracellular matrix protein | -0.0282916 |
| NEBL | nebulette | -0.0281622 |
| CDCP1 | CUB domain containing protein 1 | -0.0280698 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0277091 |
| INSIG1 | insulin induced gene 1 | -0.0275114 |
| SMYD3 | SET and MYND domain containing 3 | -0.0272584 |
| EHF | ets homologous factor | -0.0271257 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0266761 |
| ITGB4 | integrin, beta 4 | -0.0266168 |
| KRT19 | keratin 19, type I | -0.0263949 |
| PRSS3 | protease, serine, 3 | -0.0263082 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0260557 |
| USP34 | ubiquitin specific peptidase 34 | -0.02578 |
| CCND1 | cyclin D1 | -0.0256618 |
| HMGA1 | high mobility group AT-hook 1 | -0.0255683 |
| FHL2 | four and a half LIM domains 2 | -0.0255568 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0252378 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0246394 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0245054 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.0243983 |
| ABHD2 | abhydrolase domain containing 2 | -0.0241795 |
| FOXO1 | forkhead box O1 | -0.0240892 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.0239599 |
| KLF3 | Kruppel-like factor 3 (basic) | -0.0238968 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0238947 |
| FERMT1 | fermitin family member 1 | -0.0237653 |
| PTCH1 | patched 1 | -0.0237652 |
