| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tolmetin perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tolmetin_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0935337 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0851939 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0829958 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0823774 |
| NAV2 | neuron navigator 2 | 0.071825 |
| SMAD3 | SMAD family member 3 | 0.0679733 |
| PRELID2 | PRELI domain containing 2 | 0.0638487 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0582782 |
| ATP13A3 | ATPase type 13A3 | 0.0555869 |
| RUNX1 | runt-related transcription factor 1 | 0.0544592 |
| FAM13A | family with sequence similarity 13, member A | 0.0528991 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0512192 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0471987 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0447922 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0444011 |
| GPC6 | glypican 6 | 0.0442768 |
| MSN | moesin | 0.0435954 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0435691 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0413653 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0411499 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0405799 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | 0.0404505 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0398445 |
| OGA | O-GlcNAcase | 0.0369581 |
| RPL3 | ribosomal protein L3 | 0.0368652 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0339956 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0336329 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0335567 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0331963 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0321829 |
| ZNF292 | zinc finger protein 292 | 0.0318182 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0316191 |
| CEP250 | centrosomal protein 250kDa | 0.0315756 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0314444 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0312945 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0309317 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0307347 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0304428 |
| PFKP | phosphofructokinase, platelet | 0.0300121 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0298116 |
| NBAS | neuroblastoma amplified sequence | 0.0295112 |
| DST | dystonin | 0.0290149 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0285041 |
| AHR | aryl hydrocarbon receptor | 0.0277827 |
| ADD3 | adducin 3 (gamma) | 0.0276049 |
| PCBP2 | poly(rC) binding protein 2 | 0.0275305 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0274643 |
| SBF2 | SET binding factor 2 | 0.026615 |
| FAM3C | family with sequence similarity 3, member C | 0.0264666 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0260375 |
| ANXA1 | annexin A1 | 0.0259177 |
| APP | amyloid beta (A4) precursor protein | 0.0259166 |
| LRRC49 | leucine rich repeat containing 49 | 0.0258178 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0257462 |
| MYOF | myoferlin | 0.0256077 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0254918 |
| ASPH | aspartate beta-hydroxylase | 0.0252398 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0246689 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0246093 |
| TXNRD1 | thioredoxin reductase 1 | 0.0244129 |
| RBM33 | RNA binding motif protein 33 | 0.0241084 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0239342 |
| AHNAK | AHNAK nucleoprotein | 0.023847 |
| FLNB | filamin B, beta | 0.0238254 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0237252 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0236154 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0235962 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0230517 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0228526 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0227289 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0224574 |
| TMSB4X | thymosin beta 4, X-linked | 0.0224031 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0223942 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0223059 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0222892 |
| RPS2 | ribosomal protein S2 | 0.0221846 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.021981 |
| KLC1 | kinesin light chain 1 | 0.0218401 |
| CD109 | CD109 molecule | 0.0217197 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0216835 |
| XPO1 | exportin 1 | 0.0216481 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0213615 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0213083 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0212959 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.021109 |
| TPM3 | tropomyosin 3 | 0.0211068 |
| CCNY | cyclin Y | 0.02097 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0209233 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0208816 |
| RAD51B | RAD51 paralog B | 0.0208615 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0208001 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0207377 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | 0.0207143 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0206141 |
| ANGPTL4 | angiopoietin-like 4 | 0.0206076 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0206041 |
| IL6ST | interleukin 6 signal transducer | 0.0203127 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0202822 |
| MED13L | mediator complex subunit 13-like | 0.020271 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0200566 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.349746 |
| VIM | vimentin | -0.199123 |
| TMSB10 | thymosin beta 10 | -0.135692 |
| FTL | ferritin, light polypeptide | -0.126437 |
| LOX | lysyl oxidase | -0.121989 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.117551 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.109675 |
| STC1 | stanniocalcin 1 | -0.103563 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0892137 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0771511 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0749988 |
| RAB1A | RAB1A, member RAS oncogene family | -0.073457 |
| RPLP1 | ribosomal protein, large, P1 | -0.0733386 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0730057 |
| NRG1 | neuregulin 1 | -0.0682508 |
| GLCCI1 | glucocorticoid induced 1 | -0.067779 |
| EGR1 | early growth response 1 | -0.0652602 |
| FN1 | fibronectin 1 | -0.063598 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0612527 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.061152 |
| IER3 | immediate early response 3 | -0.0606768 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0604859 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.059524 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0590987 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0582474 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0565732 |
| S100A6 | S100 calcium binding protein A6 | -0.0550355 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0533758 |
| PTMA | prothymosin, alpha | -0.0506554 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.050554 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0495151 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0488697 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0480307 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.047349 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0461205 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0460749 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0455387 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0451851 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0450673 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0446087 |
| RPL35A | ribosomal protein L35a | -0.0444535 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0433972 |
| NDRG1 | N-myc downstream regulated 1 | -0.0426785 |
| RPL28 | ribosomal protein L28 | -0.040644 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0405794 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0402465 |
| RPS6 | ribosomal protein S6 | -0.0396935 |
| HMGA1 | high mobility group AT-hook 1 | -0.0392897 |
| RPS19 | ribosomal protein S19 | -0.0379384 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0375746 |
| RPS21 | ribosomal protein S21 | -0.0371285 |
| S100A10 | S100 calcium binding protein A10 | -0.0371112 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0369195 |
| LDHA | lactate dehydrogenase A | -0.0365337 |
| RPS8 | ribosomal protein S8 | -0.0363762 |
| NTN4 | netrin 4 | -0.0361184 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0353787 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0349032 |
| MT2A | metallothionein 2A | -0.0342886 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0341294 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0339435 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.033901 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0336634 |
| TMEM165 | transmembrane protein 165 | -0.0336598 |
| VRK2 | vaccinia related kinase 2 | -0.0336356 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0336066 |
| HLA-B | major histocompatibility complex, class I, B | -0.0335778 |
| RPL34 | ribosomal protein L34 | -0.0335077 |
| CA12 | carbonic anhydrase XII | -0.0333693 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0331635 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0326826 |
| CLMP | CXADR-like membrane protein | -0.0325312 |
| RPLP2 | ribosomal protein, large, P2 | -0.032417 |
| RPS24 | ribosomal protein S24 | -0.032346 |
| B2M | beta-2-microglobulin | -0.0319937 |
| RPL31 | ribosomal protein L31 | -0.0312761 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0311937 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0310908 |
| OSMR | oncostatin M receptor | -0.0307578 |
| TGFB1 | transforming growth factor, beta 1 | -0.0304756 |
| DNER | delta/notch-like EGF repeat containing | -0.0303795 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0303324 |
| AADAC | arylacetamide deacetylase | -0.0302551 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | -0.0299048 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0298772 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0291279 |
| RNF24 | ring finger protein 24 | -0.028723 |
| RPS29 | ribosomal protein S29 | -0.0286261 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0285962 |
| GLIS3 | GLIS family zinc finger 3 | -0.0282815 |
| MYADM | myeloid-associated differentiation marker | -0.0282097 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0278689 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0276508 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0272659 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0270236 |
| FBXO11 | F-box protein 11 | -0.02688 |
| OXSR1 | oxidative stress responsive 1 | -0.0266124 |
| GNAS | GNAS complex locus | -0.0265395 |
| TMEM263 | transmembrane protein 263 | -0.0264822 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0263882 |
