| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tolmetin perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tolmetin_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.133011 |
| RPL3 | ribosomal protein L3 | 0.108919 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0907947 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0864168 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0821481 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0752345 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0658187 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0645527 |
| NUP58 | nucleoporin 58 | 0.0642888 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0539228 |
| EZR | ezrin | 0.053674 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0532887 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0528098 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0519222 |
| RPS2 | ribosomal protein S2 | 0.0518526 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0502559 |
| PCBP2 | poly(rC) binding protein 2 | 0.0493817 |
| NCKAP1 | NCK-associated protein 1 | 0.0489274 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0466018 |
| PDGFC | platelet derived growth factor C | 0.0465162 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0464597 |
| ENO1 | enolase 1, (alpha) | 0.0460166 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0442933 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.042945 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0426914 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0421066 |
| SET | SET nuclear proto-oncogene | 0.0415308 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0415232 |
| ZNF292 | zinc finger protein 292 | 0.0398093 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0395971 |
| CCNL1 | cyclin L1 | 0.0388896 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0379558 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0372036 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0371813 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0359862 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0359744 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0359703 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0358649 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0358321 |
| SBF2 | SET binding factor 2 | 0.0354789 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0353441 |
| PTK2 | protein tyrosine kinase 2 | 0.0353428 |
| ZNF148 | zinc finger protein 148 | 0.0346473 |
| GOLGA4 | golgin A4 | 0.0344539 |
| RNF145 | ring finger protein 145 | 0.034395 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0341979 |
| MSN | moesin | 0.0341717 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0339749 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0336858 |
| SETD5 | SET domain containing 5 | 0.0335224 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0331386 |
| ARGLU1 | arginine and glutamate rich 1 | 0.033115 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0323973 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0323372 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0321222 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0320247 |
| PDS5B | PDS5 cohesin associated factor B | 0.0317714 |
| INSIG2 | insulin induced gene 2 | 0.0312748 |
| RPS18 | ribosomal protein S18 | 0.0311719 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.03105 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0309945 |
| DST | dystonin | 0.0308986 |
| PNN | pinin, desmosome associated protein | 0.0306808 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0300492 |
| XPOT | exportin, tRNA | 0.0297483 |
| CHD7 | chromodomain helicase DNA binding protein 7 | 0.0296603 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0295608 |
| MED13L | mediator complex subunit 13-like | 0.0291605 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0290929 |
| RBM26 | RNA binding motif protein 26 | 0.0290375 |
| RBM39 | RNA binding motif protein 39 | 0.0290186 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0290067 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0287841 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0287658 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | 0.0285771 |
| HDGF | hepatoma-derived growth factor | 0.0285225 |
| PRELID2 | PRELI domain containing 2 | 0.0283584 |
| YME1L1 | YME1-like 1 ATPase | 0.0282298 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0281902 |
| LOXL3 | lysyl oxidase-like 3 | 0.0280305 |
| SNX9 | sorting nexin 9 | 0.027972 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0279366 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0278201 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0273422 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.027162 |
| RPS3 | ribosomal protein S3 | 0.0271588 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0270507 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0270155 |
| TPI1 | triosephosphate isomerase 1 | 0.0268526 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0268245 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0267262 |
| TMEM65 | transmembrane protein 65 | 0.0265905 |
| SSBP2 | single-stranded DNA binding protein 2 | 0.0263865 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0259141 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0258512 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0258147 |
| SP3 | Sp3 transcription factor | 0.0257864 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0256244 |
| RIOK3 | RIO kinase 3 | 0.0255064 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0254707 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.371705 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.181014 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.123324 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.122264 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0780214 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0770948 |
| FOXP1 | forkhead box P1 | -0.0733069 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0724228 |
| CCND1 | cyclin D1 | -0.0723473 |
| BMP10 | bone morphogenetic protein 10 | -0.062494 |
| PTMA | prothymosin, alpha | -0.0602275 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0595006 |
| RPS6 | ribosomal protein S6 | -0.0569289 |
| RPLP1 | ribosomal protein, large, P1 | -0.0545469 |
| LDHA | lactate dehydrogenase A | -0.0492917 |
| ACTG1 | actin gamma 1 | -0.049157 |
| NBEA | neurobeachin | -0.0472373 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0446228 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 | -0.044455 |
| S100A6 | S100 calcium binding protein A6 | -0.0408085 |
| RPS8 | ribosomal protein S8 | -0.0399881 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0398292 |
| EXT1 | exostosin glycosyltransferase 1 | -0.038611 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0376171 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0365457 |
| RPL28 | ribosomal protein L28 | -0.0351965 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0340372 |
| EGFR | epidermal growth factor receptor | -0.0333363 |
| MYO5C | myosin VC | -0.0327075 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0320749 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0316015 |
| S100A9 | S100 calcium binding protein A9 | -0.0312222 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0308755 |
| RPL34 | ribosomal protein L34 | -0.0306859 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0305092 |
| S100A4 | S100 calcium binding protein A4 | -0.0303316 |
| RPS13 | ribosomal protein S13 | -0.0299842 |
| RPS24 | ribosomal protein S24 | -0.0299077 |
| RPL27A | ribosomal protein L27a | -0.0298354 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0287222 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.027597 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.027533 |
| DUSP6 | dual specificity phosphatase 6 | -0.0274435 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0273679 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0273553 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0270592 |
| GNAS | GNAS complex locus | -0.0268851 |
| RPLP0 | ribosomal protein, large, P0 | -0.0267709 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.0264493 |
| AHNAK | AHNAK nucleoprotein | -0.0261495 |
| FUS | FUS RNA binding protein | -0.025959 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0256375 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0253853 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0253172 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0249575 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0245114 |
| RPL38 | ribosomal protein L38 | -0.0244677 |
| RPL36A | ribosomal protein L36a | -0.024293 |
| HEG1 | heart development protein with EGF-like domains 1 | -0.0240793 |
| AHI1 | Abelson helper integration site 1 | -0.0240716 |
| HLA-B | major histocompatibility complex, class I, B | -0.023786 |
| CYB5B | cytochrome b5 type B (outer mitochondrial membrane) | -0.0236524 |
| NFIA | nuclear factor I/A | -0.0236352 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.023619 |
| NAV2 | neuron navigator 2 | -0.0235546 |
| FTL | ferritin, light polypeptide | -0.0233649 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0232138 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0231963 |
| HJURP | Holliday junction recognition protein | -0.0231132 |
| DIAPH3 | diaphanous-related formin 3 | -0.0229505 |
| S100A10 | S100 calcium binding protein A10 | -0.0225056 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0224381 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0223172 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0223018 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0222686 |
| BSG | basigin (Ok blood group) | -0.0222378 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | -0.0222222 |
| CCNI | cyclin I | -0.0221854 |
| RPL35A | ribosomal protein L35a | -0.0221519 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.021874 |
| CUX1 | cut-like homeobox 1 | -0.0217993 |
| USP15 | ubiquitin specific peptidase 15 | -0.0214509 |
| RPL31 | ribosomal protein L31 | -0.0212523 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0212024 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0209562 |
| ATG7 | autophagy related 7 | -0.0209091 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | -0.0208482 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0208151 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0207125 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0205823 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0205328 |
| SPRY2 | sprouty homolog 2 (Drosophila) | -0.0204092 |
| CENATAC | centrosomal AT-AC splicing factor | -0.0201469 |
| RPS25 | ribosomal protein S25 | -0.0201337 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0199729 |
| SSH2 | slingshot protein phosphatase 2 | -0.0199506 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0199353 |
| RPL19 | ribosomal protein L19 | -0.0198048 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0197807 |
| RPS16 | ribosomal protein S16 | -0.0195888 |
