| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tolmetin perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tolmetin_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0809176 |
| EFNA5 | ephrin-A5 | 0.0676033 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0598977 |
| FAM13A | family with sequence similarity 13, member A | 0.0519806 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0509871 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0502653 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.049763 |
| SON | SON DNA binding protein | 0.0477622 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0464534 |
| CENPE | centromere protein E, 312kDa | 0.0444131 |
| AHNAK | AHNAK nucleoprotein | 0.0440573 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0419698 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0412212 |
| MSN | moesin | 0.0408295 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0404186 |
| PRRC2C | proline-rich coiled-coil 2C | 0.039559 |
| RBM39 | RNA binding motif protein 39 | 0.039368 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0385588 |
| LOX | lysyl oxidase | 0.0370339 |
| RASA2 | RAS p21 protein activator 2 | 0.036261 |
| PTMA | prothymosin, alpha | 0.0358695 |
| ASPH | aspartate beta-hydroxylase | 0.0357597 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0347089 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0337854 |
| OXSR1 | oxidative stress responsive 1 | 0.0333832 |
| TMF1 | TATA element modulatory factor 1 | 0.0333807 |
| FAM20C | family with sequence similarity 20, member C | 0.0332013 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0330964 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0329725 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0328808 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | 0.0328116 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0327909 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0322913 |
| CENPF | centromere protein F, 350/400kDa | 0.0318975 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0315539 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0311779 |
| NAV2 | neuron navigator 2 | 0.0311384 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 0.0310796 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0308647 |
| ANLN | anillin, actin binding protein | 0.0308573 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0307888 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0307574 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0303484 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0297737 |
| SUCO | SUN domain containing ossification factor | 0.0293522 |
| TNS3 | tensin 3 | 0.0290994 |
| RUNX2 | runt-related transcription factor 2 | 0.0284056 |
| ARRDC3 | arrestin domain containing 3 | 0.0281615 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0277304 |
| PTBP2 | polypyrimidine tract binding protein 2 | 0.0274669 |
| ATG7 | autophagy related 7 | 0.0273942 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0273514 |
| CADM1 | cell adhesion molecule 1 | 0.0272972 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0270594 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0270115 |
| PRKCA | protein kinase C, alpha | 0.0268174 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.0266481 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0265757 |
| BLCAP | bladder cancer associated protein | 0.0264149 |
| PRELID2 | PRELI domain containing 2 | 0.026396 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0261799 |
| RPL3 | ribosomal protein L3 | 0.0260368 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | 0.0260116 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0259797 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.025789 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0256585 |
| EP300 | E1A binding protein p300 | 0.0253791 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0252799 |
| AUH | AU RNA binding protein/enoyl-CoA hydratase | 0.0252305 |
| SFXN1 | sideroflexin 1 | 0.024969 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.024787 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0245872 |
| TENM2 | teneurin transmembrane protein 2 | 0.0245568 |
| PLEC | plectin | 0.024493 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase | 0.0242949 |
| C1S | complement component 1, s subcomponent | 0.0242651 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0242496 |
| B2M | beta-2-microglobulin | 0.0241649 |
| CAVIN1 | caveolae associated protein 1 | 0.0239874 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0238957 |
| FAT1 | FAT atypical cadherin 1 | 0.0238585 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0235739 |
| MYO10 | myosin X | 0.0235554 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0235482 |
| RANBP2 | RAN binding protein 2 | 0.023432 |
| MATR3 | matrin 3 | 0.0233884 |
| UIMC1 | ubiquitin interaction motif containing 1 | 0.0233864 |
| INSIG2 | insulin induced gene 2 | 0.0233839 |
| IL6ST | interleukin 6 signal transducer | 0.023322 |
| SYNGAP1 | synaptic Ras GTPase activating protein 1 | 0.0232523 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.023126 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0230661 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0228927 |
| FUS | FUS RNA binding protein | 0.0227183 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0226948 |
| MED13L | mediator complex subunit 13-like | 0.0226402 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0225949 |
| URI1 | URI1, prefoldin-like chaperone | 0.0223932 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0223834 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0223667 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.24461 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.145846 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.14204 |
| MT2A | metallothionein 2A | -0.122249 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.106903 |
| TMSB10 | thymosin beta 10 | -0.105268 |
| HLA-B | major histocompatibility complex, class I, B | -0.100825 |
| FN1 | fibronectin 1 | -0.10081 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0951298 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0830689 |
| NDRG1 | N-myc downstream regulated 1 | -0.0828434 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0801023 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0694043 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0689055 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0657706 |
| POTEF | POTE ankyrin domain family, member F | -0.0636723 |
| EGR1 | early growth response 1 | -0.0633848 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0607172 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0565899 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0564922 |
| COL1A2 | collagen, type I, alpha 2 | -0.0543309 |
| RTN4 | reticulon 4 | -0.0535471 |
| CALD1 | caldesmon 1 | -0.0535081 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0527736 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0495439 |
| FTL | ferritin, light polypeptide | -0.0494112 |
| HM13 | histocompatibility (minor) 13 | -0.0493452 |
| MEF2A | myocyte enhancer factor 2A | -0.0472023 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0447623 |
| STC1 | stanniocalcin 1 | -0.0446883 |
| FAM133B | family with sequence similarity 133, member B | -0.0443313 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.044305 |
| ENO1 | enolase 1, (alpha) | -0.0439863 |
| ZNF395 | zinc finger protein 395 | -0.0403604 |
| CD44 | CD44 molecule (Indian blood group) | -0.0398991 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0398213 |
| NAV1 | neuron navigator 1 | -0.0395082 |
| VIM | vimentin | -0.0394048 |
| CALU | calumenin | -0.0391761 |
| NRXN3 | neurexin 3 | -0.038833 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0386338 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0381303 |
| EGFR | epidermal growth factor receptor | -0.0378506 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0374825 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.036445 |
| OAF | OAF homolog (Drosophila) | -0.0364154 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0357336 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.034966 |
| RPL34 | ribosomal protein L34 | -0.0349454 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0345351 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | -0.0337813 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0337381 |
| RPS3 | ribosomal protein S3 | -0.0335673 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0329225 |
| HMGA2 | high mobility group AT-hook 2 | -0.0324925 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0324047 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.032287 |
| SETX | senataxin | -0.0322869 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | -0.0321303 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0321144 |
| CA12 | carbonic anhydrase XII | -0.0320786 |
| CLTC | clathrin, heavy chain (Hc) | -0.0320493 |
| RAP1B | RAP1B, member of RAS oncogene family | -0.0318747 |
| CAPN2 | calpain 2, (m/II) large subunit | -0.0314381 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0311355 |
| SRP54 | signal recognition particle 54kDa | -0.0307008 |
| CLIC4 | chloride intracellular channel 4 | -0.0306473 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0301648 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0297161 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.029643 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0294757 |
| AOPEP | aminopeptidase O (putative) | -0.0293797 |
| MYO1E | myosin IE | -0.0292458 |
| LMNA | lamin A/C | -0.0291591 |
| SYNPO | synaptopodin | -0.0291007 |
| THBS1 | thrombospondin 1 | -0.0290897 |
| TPM1 | tropomyosin 1 (alpha) | -0.0289264 |
| RPLP1 | ribosomal protein, large, P1 | -0.0289173 |
| SAR1A | secretion associated, Ras related GTPase 1A | -0.0287361 |
| MYOF | myoferlin | -0.0285664 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0284788 |
| ANXA2 | annexin A2 | -0.0284036 |
| CDK6 | cyclin-dependent kinase 6 | -0.028295 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0280072 |
| AK1 | adenylate kinase 1 | -0.0280068 |
| PCNX1 | pecanex 1 | -0.0279526 |
| NF1 | neurofibromin 1 | -0.027791 |
| CTSB | cathepsin B | -0.027361 |
| AGRN | agrin | -0.0272749 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0271924 |
| JUN | jun proto-oncogene | -0.0269012 |
| RC3H1 | ring finger and CCCH-type domains 1 | -0.0261345 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0261265 |
| BPTF | bromodomain PHD finger transcription factor | -0.0260438 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0259406 |
| PARD3 | par-3 family cell polarity regulator | -0.0258126 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0256916 |
| NBEAL1 | neurobeachin-like 1 | -0.0256257 |
| TPM4 | tropomyosin 4 | -0.0256006 |
| LDHA | lactate dehydrogenase A | -0.0255349 |
