| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tolmetin perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tolmetin_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.186822 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.108923 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.108154 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0947436 |
| CEP250 | centrosomal protein 250kDa | 0.0843525 |
| CENPF | centromere protein F, 350/400kDa | 0.0792887 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0785978 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0753873 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0734139 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0725202 |
| TPI1 | triosephosphate isomerase 1 | 0.0722025 |
| YAP1 | Yes-associated protein 1 | 0.0702089 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0697145 |
| SET | SET nuclear proto-oncogene | 0.0684097 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0650224 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0614746 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0612363 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0600254 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.059535 |
| TPX2 | TPX2, microtubule-associated | 0.057654 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0557774 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0555697 |
| KIAA1328 | KIAA1328 | 0.055303 |
| FMNL2 | formin-like 2 | 0.054761 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0536928 |
| MAPKAP1 | mitogen-activated protein kinase associated protein 1 | 0.0525924 |
| RPS3 | ribosomal protein S3 | 0.0517219 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0514041 |
| NUP58 | nucleoporin 58 | 0.0513545 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0507004 |
| MSN | moesin | 0.0504345 |
| MKI67 | marker of proliferation Ki-67 | 0.0503236 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0502131 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0501655 |
| H1-4 | H1.4 linker histone, cluster member | 0.049991 |
| LDHA | lactate dehydrogenase A | 0.0496503 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0491325 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0488758 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0484984 |
| KIF5B | kinesin family member 5B | 0.0484939 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.048185 |
| AHNAK | AHNAK nucleoprotein | 0.0479127 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0475173 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0467045 |
| CANX | calnexin | 0.046666 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0465046 |
| ECT2 | epithelial cell transforming 2 | 0.0459838 |
| ANLN | anillin, actin binding protein | 0.045866 |
| CPNE1 | copine I | 0.0453562 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0452423 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0445162 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0443945 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0436804 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0435425 |
| SMAD3 | SMAD family member 3 | 0.0429538 |
| RBM39 | RNA binding motif protein 39 | 0.0428592 |
| PTMA | prothymosin, alpha | 0.0425126 |
| FNDC3B | fibronectin type III domain containing 3B | 0.042469 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0423397 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0420244 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0417294 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0416675 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0416067 |
| HMGB2 | high mobility group box 2 | 0.041385 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0413614 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0411886 |
| YME1L1 | YME1-like 1 ATPase | 0.0408268 |
| APP | amyloid beta (A4) precursor protein | 0.040753 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0405901 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0404831 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0403416 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0401823 |
| ANXA1 | annexin A1 | 0.0389215 |
| PAPOLA | poly(A) polymerase alpha | 0.0388776 |
| NAV2 | neuron navigator 2 | 0.0387369 |
| RPS17 | ribosomal protein S17 | 0.0386512 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0386037 |
| KIF4A | kinesin family member 4A | 0.0384685 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0384453 |
| FLNB | filamin B, beta | 0.0381519 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0380099 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0379732 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0379669 |
| TPM3 | tropomyosin 3 | 0.0374058 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0374021 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0372423 |
| RPL23 | ribosomal protein L23 | 0.037129 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0370008 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0369722 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0366955 |
| KIF23 | kinesin family member 23 | 0.0366366 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0364244 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0360784 |
| RRBP1 | ribosome binding protein 1 | 0.0360765 |
| FLNA | filamin A, alpha | 0.0357976 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0351762 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | 0.0345964 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0345602 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.034545 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0344126 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.251968 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0688638 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0465351 |
| MAP1B | microtubule-associated protein 1B | -0.0449341 |
| FNIP1 | folliculin interacting protein 1 | -0.0445835 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0436188 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0425241 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | -0.0424163 |
| TUBA1B | tubulin, alpha 1b | -0.0392713 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0385558 |
| BSG | basigin (Ok blood group) | -0.0377287 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0361815 |
| IGF2 | insulin-like growth factor 2 | -0.0356614 |
| PRKCA | protein kinase C, alpha | -0.0352034 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0351022 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.030679 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0304578 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0291564 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0290025 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0288385 |
| KLHL24 | kelch-like family member 24 | -0.0282965 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0280009 |
| PRR16 | proline rich 16 | -0.0276381 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0274397 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0274294 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0271828 |
| HIPK3 | homeodomain interacting protein kinase 3 | -0.0269304 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.0267789 |
| RIGI | RNA sensor RIG-I | -0.0267109 |
| CEBPZ | CCAAT/enhancer binding protein (C/EBP), zeta | -0.0257512 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0256666 |
| USO1 | USO1 vesicle transport factor | -0.0252696 |
| ST3GAL3 | ST3 beta-galactoside alpha-2,3-sialyltransferase 3 | -0.0252519 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0252015 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0251289 |
| JMJD1C | jumonji domain containing 1C | -0.0250867 |
| AEBP2 | AE binding protein 2 | -0.0250462 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0249893 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0247386 |
| RNF11 | ring finger protein 11 | -0.0246757 |
| MYO1D | myosin ID | -0.0246258 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0244689 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0239818 |
| PODXL | podocalyxin-like | -0.0239576 |
| TMEM165 | transmembrane protein 165 | -0.0238283 |
| HMGA1 | high mobility group AT-hook 1 | -0.0238229 |
| ZWILCH | zwilch kinetochore protein | -0.0238037 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0236676 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0236366 |
| TAGLN2 | transgelin 2 | -0.0235612 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0234832 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0233542 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.0231032 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0230554 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0229036 |
| RNASEH2A | ribonuclease H2, subunit A | -0.0227474 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.022654 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0225983 |
| SMCR8 | Smith-Magenis syndrome chromosome region, candidate 8 | -0.0224856 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0221477 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0220092 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) | -0.0219539 |
| CCPG1 | cell cycle progression 1 | -0.0212761 |
| CREBRF | CREB3 regulatory factor | -0.0212544 |
| HMGA2 | high mobility group AT-hook 2 | -0.0212282 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0212166 |
| SIK2 | salt-inducible kinase 2 | -0.0211607 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0210518 |
| MED26 | mediator complex subunit 26 | -0.0209482 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0208508 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0208308 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0208001 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 | -0.0207347 |
| LAMA5 | laminin, alpha 5 | -0.0207156 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0206372 |
| MYADM | myeloid-associated differentiation marker | -0.0205766 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0203108 |
| MXD1 | MAX dimerization protein 1 | -0.0203102 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0202858 |
| MTERF4 | mitochondrial transcription termination factor 4 | -0.0202836 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0202369 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0202089 |
| YEATS2 | YEATS domain containing 2 | -0.0202065 |
| HLA-C | major histocompatibility complex, class I, C | -0.0201814 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0201713 |
| DENND5B | DENN/MADD domain containing 5B | -0.0201393 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.020097 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0200243 |
| ITGAV | integrin, alpha V | -0.0199907 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0199463 |
| ULK1 | unc-51 like autophagy activating kinase 1 | -0.0199405 |
| ERCC1 | excision repair cross-complementation group 1 | -0.019719 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0196532 |
| EP400 | E1A binding protein p400 | -0.0194323 |
| FLCN | folliculin | -0.0193733 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0192324 |
| MDM4 | MDM4, p53 regulator | -0.0191173 |
| NALCN | sodium leak channel, non selective | -0.0190004 |
| WASHC4 | WASH complex subunit 4 | -0.018988 |
| GTF2B | general transcription factor IIB | -0.0189642 |
