| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tolmetin perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tolmetin_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.117427 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0876587 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0834848 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0643103 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0604999 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0587649 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.054918 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.052398 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0522591 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0505627 |
| PTK2 | protein tyrosine kinase 2 | 0.0487563 |
| AHR | aryl hydrocarbon receptor | 0.0480243 |
| ASPH | aspartate beta-hydroxylase | 0.0477903 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0476824 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0468782 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0462008 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0433711 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.043077 |
| FAT1 | FAT atypical cadherin 1 | 0.0406407 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.040443 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0399213 |
| ZNF292 | zinc finger protein 292 | 0.0397158 |
| TPM3 | tropomyosin 3 | 0.0378369 |
| CAB39 | calcium binding protein 39 | 0.0378338 |
| SMAD3 | SMAD family member 3 | 0.0368986 |
| FAM13A | family with sequence similarity 13, member A | 0.0365332 |
| PRELID2 | PRELI domain containing 2 | 0.0361741 |
| NEK7 | NIMA-related kinase 7 | 0.0361097 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0359046 |
| XPO1 | exportin 1 | 0.0353752 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0350023 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0344059 |
| DST | dystonin | 0.0342113 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0341853 |
| SEPTIN7 | septin 7 | 0.0341459 |
| APP | amyloid beta (A4) precursor protein | 0.0340645 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0340358 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0336002 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0322048 |
| AFDN | afadin, adherens junction formation factor | 0.0320946 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0320055 |
| RPS2 | ribosomal protein S2 | 0.0311959 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0309369 |
| MSN | moesin | 0.0308425 |
| PELO | pelota homolog (Drosophila) | 0.030548 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0299496 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0295806 |
| IL6ST | interleukin 6 signal transducer | 0.0294436 |
| RNF145 | ring finger protein 145 | 0.0293126 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0290575 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0285553 |
| YME1L1 | YME1-like 1 ATPase | 0.0281177 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.027752 |
| CD44 | CD44 molecule (Indian blood group) | 0.027659 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0273254 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0273209 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0270815 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.026997 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0269111 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0268659 |
| ARRDC3 | arrestin domain containing 3 | 0.0268246 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0266637 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0265598 |
| OGA | O-GlcNAcase | 0.0263129 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0261267 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0261108 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0260071 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0259393 |
| SLTM | SAFB-like, transcription modulator | 0.0259222 |
| RPL3 | ribosomal protein L3 | 0.0258955 |
| SMYD3 | SET and MYND domain containing 3 | 0.0256851 |
| TFG | TRK-fused gene | 0.0255903 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.025484 |
| SVIL | supervillin | 0.0253659 |
| ANLN | anillin, actin binding protein | 0.0253513 |
| CENPF | centromere protein F, 350/400kDa | 0.0246964 |
| CD109 | CD109 molecule | 0.024314 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0242102 |
| NCKAP1 | NCK-associated protein 1 | 0.0241119 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0235235 |
| JMJD1C | jumonji domain containing 1C | 0.0234044 |
| MATR3 | matrin 3 | 0.0233613 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0233202 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0232472 |
| RTN4 | reticulon 4 | 0.0231694 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0230509 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0229514 |
| YAP1 | Yes-associated protein 1 | 0.022672 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0222244 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.022219 |
| MT2A | metallothionein 2A | 0.0220918 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0220781 |
| RIOK3 | RIO kinase 3 | 0.0218205 |
| AHNAK | AHNAK nucleoprotein | 0.0216614 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0216298 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0214752 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0214746 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0214619 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0214575 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0214314 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.264255 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.248792 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.232342 |
| FN1 | fibronectin 1 | -0.19783 |
| HMGA2 | high mobility group AT-hook 2 | -0.120398 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.098254 |
| SQSTM1 | sequestosome 1 | -0.0765456 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0709326 |
| CANX | calnexin | -0.0687899 |
| HLA-B | major histocompatibility complex, class I, B | -0.0680011 |
| STC2 | stanniocalcin 2 | -0.0647373 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0644925 |
| GLIS3 | GLIS family zinc finger 3 | -0.0610392 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0608427 |
| TMSB10 | thymosin beta 10 | -0.0514312 |
| PTMA | prothymosin, alpha | -0.0494587 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0489667 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.047695 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0465569 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.04433 |
| AEBP2 | AE binding protein 2 | -0.0442695 |
| RAI14 | retinoic acid induced 14 | -0.0440437 |
| TMEM165 | transmembrane protein 165 | -0.0429587 |
| EFNA5 | ephrin-A5 | -0.0417445 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0415489 |
| NDRG1 | N-myc downstream regulated 1 | -0.0411335 |
| S100A6 | S100 calcium binding protein A6 | -0.0407462 |
| INTS6 | integrator complex subunit 6 | -0.0406487 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0402421 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0372697 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0367626 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.035943 |
| FTL | ferritin, light polypeptide | -0.0338638 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0331506 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0330378 |
| PALLD | palladin, cytoskeletal associated protein | -0.0326228 |
| SYT1 | synaptotagmin I | -0.0321425 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0319015 |
| FBN1 | fibrillin 1 | -0.0316946 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0305509 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0297572 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0296389 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0290873 |
| HMGA1 | high mobility group AT-hook 1 | -0.0289714 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.028937 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0288383 |
| ITGA1 | integrin, alpha 1 | -0.028524 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0279096 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0276568 |
| HLA-A | major histocompatibility complex, class I, A | -0.0266981 |
| EGR1 | early growth response 1 | -0.0266733 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0265631 |
| LMNA | lamin A/C | -0.0265071 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0263266 |
| ACTG1 | actin gamma 1 | -0.0261411 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0256565 |
| AHI1 | Abelson helper integration site 1 | -0.0254076 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0243115 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0242562 |
| USP34 | ubiquitin specific peptidase 34 | -0.0237925 |
| LOX | lysyl oxidase | -0.0235847 |
| RANBP17 | RAN binding protein 17 | -0.0235493 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0234842 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0231377 |
| RBM47 | RNA binding motif protein 47 | -0.0229786 |
| TNS3 | tensin 3 | -0.0229051 |
| LRRC23 | leucine rich repeat containing 23 | -0.0225881 |
| KRT81 | keratin 81, type II | -0.0222484 |
| IL6 | interleukin 6 | -0.0221683 |
| FAM20C | family with sequence similarity 20, member C | -0.0220621 |
| TMEM263 | transmembrane protein 263 | -0.0219419 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0217394 |
| CALR | calreticulin | -0.021717 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0213913 |
| ADIPOR2 | adiponectin receptor 2 | -0.0213774 |
| VEGFA | vascular endothelial growth factor A | -0.0211826 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0211279 |
| ATN1 | atrophin 1 | -0.020755 |
| RASAL2 | RAS protein activator like 2 | -0.0206368 |
| CTSD | cathepsin D | -0.020419 |
| TGFB1 | transforming growth factor, beta 1 | -0.0202572 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0197555 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0194682 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0193897 |
| CADM1 | cell adhesion molecule 1 | -0.0191268 |
| GNAS | GNAS complex locus | -0.019075 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0190747 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0190694 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0186917 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0185702 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0183928 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0183724 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0180044 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0179125 |
| CDK13 | cyclin-dependent kinase 13 | -0.017593 |
| BSG | basigin (Ok blood group) | -0.0175086 |
| MYADM | myeloid-associated differentiation marker | -0.0171732 |
| ARF4 | ADP-ribosylation factor 4 | -0.0171682 |
| VCL | vinculin | -0.0171571 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0169266 |
