| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Tomivosertib perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Tomivosertib_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.136605 |
| MT2A | metallothionein 2A | 0.0922091 |
| RPS6 | ribosomal protein S6 | 0.0869677 |
| B2M | beta-2-microglobulin | 0.0864132 |
| RPS8 | ribosomal protein S8 | 0.0786536 |
| ANXA1 | annexin A1 | 0.0773583 |
| DSTN | destrin (actin depolymerizing factor) | 0.0558536 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0547739 |
| POTEF | POTE ankyrin domain family, member F | 0.0537204 |
| PTMA | prothymosin, alpha | 0.0533016 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0515613 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0507954 |
| NDRG1 | N-myc downstream regulated 1 | 0.050631 |
| GOLGA4 | golgin A4 | 0.048479 |
| SQLE | squalene epoxidase | 0.0478193 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0446456 |
| ENO1 | enolase 1, (alpha) | 0.0434289 |
| FTL | ferritin, light polypeptide | 0.042263 |
| RPL11 | ribosomal protein L11 | 0.0416003 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | 0.0415599 |
| RPS12 | ribosomal protein S12 | 0.0413922 |
| TMSB10 | thymosin beta 10 | 0.0404514 |
| RACK1 | receptor for activated C kinase 1 | 0.0403636 |
| RPS19 | ribosomal protein S19 | 0.039037 |
| RPS13 | ribosomal protein S13 | 0.0390338 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0377275 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0377191 |
| RPS3 | ribosomal protein S3 | 0.0375243 |
| RPLP2 | ribosomal protein, large, P2 | 0.0348498 |
| RPL12 | ribosomal protein L12 | 0.0347469 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.034698 |
| DPM1 | dolichyl-phosphate mannosyltransferase polypeptide 1, catalytic subunit | 0.0345838 |
| RPL37A | ribosomal protein L37a | 0.0328401 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0325405 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.032204 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0320427 |
| RPS2 | ribosomal protein S2 | 0.0319219 |
| RPL5 | ribosomal protein L5 | 0.0318584 |
| RPLP1 | ribosomal protein, large, P1 | 0.0314179 |
| LMNA | lamin A/C | 0.0311221 |
| MT1X | metallothionein 1X | 0.0311004 |
| YBX1 | Y box binding protein 1 | 0.0309619 |
| LDHA | lactate dehydrogenase A | 0.0305398 |
| RPL37 | ribosomal protein L37 | 0.0304573 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0303821 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0301772 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | 0.0287901 |
| S100A6 | S100 calcium binding protein A6 | 0.0283972 |
| SLK | STE20-like kinase | 0.0283412 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0279742 |
| EZR | ezrin | 0.0274956 |
| ARRDC3 | arrestin domain containing 3 | 0.027457 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0269933 |
| RPS27 | ribosomal protein S27 | 0.0269386 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0268331 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0267878 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0264566 |
| RPL31 | ribosomal protein L31 | 0.0263108 |
| S100A10 | S100 calcium binding protein A10 | 0.0262444 |
| RPLP0 | ribosomal protein, large, P0 | 0.0261526 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.026069 |
| CLU | clusterin | 0.0255657 |
| SQSTM1 | sequestosome 1 | 0.0253514 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0253094 |
| MT1E | metallothionein 1E | 0.0253093 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0252718 |
| UBC | ubiquitin C | 0.0246431 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0246106 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | 0.0244368 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.0242947 |
| KRT17 | keratin 17, type I | 0.0242797 |
| CD44 | CD44 molecule (Indian blood group) | 0.0242309 |
| RPL8 | ribosomal protein L8 | 0.0242159 |
| CSTB | cystatin B (stefin B) | 0.023987 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0239838 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0239799 |
| RNF145 | ring finger protein 145 | 0.0239625 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | 0.0238434 |
| PCBP2 | poly(rC) binding protein 2 | 0.0237777 |
| ADM | adrenomedullin | 0.0237231 |
| RPS25 | ribosomal protein S25 | 0.0236332 |
| TOP1 | topoisomerase (DNA) I | 0.023628 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0236042 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0230846 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0228896 |
| H1-0 | H1.0 linker histone | 0.0228787 |
| PKM | pyruvate kinase, muscle | 0.0224604 |
| RPL36 | ribosomal protein L36 | 0.022163 |
| RPL19 | ribosomal protein L19 | 0.0220842 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0218882 |
| RPL35A | ribosomal protein L35a | 0.0217646 |
| RPS21 | ribosomal protein S21 | 0.0217319 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0217062 |
| RPS14 | ribosomal protein S14 | 0.0215502 |
| RPL26 | ribosomal protein L26 | 0.0214052 |
| TXNIP | thioredoxin interacting protein | 0.021401 |
| WASF2 | WAS protein family, member 2 | 0.0213136 |
| RPS20 | ribosomal protein S20 | 0.0211788 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0211353 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.021116 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.245285 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.203339 |
| FLNB | filamin B, beta | -0.141692 |
| DPYD | dihydropyrimidine dehydrogenase | -0.122316 |
| AHNAK | AHNAK nucleoprotein | -0.101305 |
| MTSS1 | metastasis suppressor 1 | -0.0899574 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0821713 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0710483 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.070383 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0688171 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0611657 |
| PRELID2 | PRELI domain containing 2 | -0.0599311 |
| OSMR | oncostatin M receptor | -0.0584456 |
| PLEC | plectin | -0.0560661 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0554931 |
| MECOM | MDS1 and EVI1 complex locus | -0.0542948 |
| RIN2 | Ras and Rab interactor 2 | -0.0526263 |
| SULF1 | sulfatase 1 | -0.0514302 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0489348 |
| FOXO1 | forkhead box O1 | -0.0471813 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0466476 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0461892 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0441177 |
| ADAMTS16 | ADAM metallopeptidase with thrombospondin type 1 motif, 16 | -0.0436311 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0426792 |
| RIGI | RNA sensor RIG-I | -0.0425029 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0412438 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0403852 |
| BLCAP | bladder cancer associated protein | -0.0402373 |
| HSD17B2 | hydroxysteroid (17-beta) dehydrogenase 2 | -0.0402071 |
| PALLD | palladin, cytoskeletal associated protein | -0.0400581 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0400271 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0398185 |
| SMYD3 | SET and MYND domain containing 3 | -0.0395921 |
| RAD51B | RAD51 paralog B | -0.0393154 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0392276 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0385998 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0383634 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0378619 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0374424 |
| NEK7 | NIMA-related kinase 7 | -0.0372982 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0364169 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.036288 |
| EFNA5 | ephrin-A5 | -0.036102 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.035974 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0354661 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.0352794 |
| PRSS23 | protease, serine, 23 | -0.0351496 |
| ASPH | aspartate beta-hydroxylase | -0.0349606 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0342731 |
| AOPEP | aminopeptidase O (putative) | -0.0336083 |
| NAV2 | neuron navigator 2 | -0.0333988 |
| FOXP1 | forkhead box P1 | -0.0332407 |
| KIAA1217 | KIAA1217 | -0.0329461 |
| TNS3 | tensin 3 | -0.0325435 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0319808 |
| RASAL2 | RAS protein activator like 2 | -0.0318103 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0315911 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | -0.0313619 |
| EXOC4 | exocyst complex component 4 | -0.0313077 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0312089 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0305096 |
| BCL2L1 | BCL2-like 1 | -0.0302489 |
| PTK2 | protein tyrosine kinase 2 | -0.0299642 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0297908 |
| MTAP | methylthioadenosine phosphorylase | -0.0295415 |
| LAMC2 | laminin, gamma 2 | -0.0291601 |
| AMOTL1 | angiomotin like 1 | -0.0289783 |
| SULF2 | sulfatase 2 | -0.0289429 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0287913 |
| HMGA2 | high mobility group AT-hook 2 | -0.0284641 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0282936 |
| CDK6 | cyclin-dependent kinase 6 | -0.0281352 |
| SLC45A4 | solute carrier family 45, member 4 | -0.0279828 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.0277571 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0274716 |
| EGFR | epidermal growth factor receptor | -0.0271846 |
| UTRN | utrophin | -0.0271177 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.0271137 |
| DOCK9 | dedicator of cytokinesis 9 | -0.0269422 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0268711 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.025896 |
| METTL15 | methyltransferase like 15 | -0.0255325 |
| DGKH | diacylglycerol kinase, eta | -0.0252133 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0251688 |
| ITGA6 | integrin, alpha 6 | -0.025164 |
| ACTN4 | actinin, alpha 4 | -0.0248223 |
| VCL | vinculin | -0.0247116 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0245664 |
| C4BPB | complement component 4 binding protein, beta | -0.0244616 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0241231 |
| PODXL | podocalyxin-like | -0.0241125 |
| FRMD4B | FERM domain containing 4B | -0.0239749 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0239574 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0237648 |
| CNTNAP3 | contactin associated protein-like 3 | -0.0237556 |
| NIBAN2 | niban apoptosis regulator 2 | -0.0235872 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0235523 |
| PYGL | phosphorylase, glycogen, liver | -0.0230252 |
| NRCAM | neuronal cell adhesion molecule | -0.0226866 |
